Results 41 to 50 of about 2,507,328 (341)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

STUDY OF THE PETROPHYSICAL CHARACTERISTICS OF ROCKS FROM THE LIBWA FIELD IN THE PINDA RESERVOIR IN THE D.R. CONGO COASTAL BASIN [PDF]

Romanian Journal of Petroleum & Gas Technology
The Libwa field, located offshore the Democratic Republic of Congo (DRC), has significant potential for hydrocarbon exploitation, particularly in the southern part, which remains unexploited.
André Yelembangu Ngwey, Jean Iyolo Lungembo, Dona Kampata Mbwelele, Gustave Ngalamulume Bantu, Néhémie Bikayi Tshiani, Rachidi Opuluku   +5 more
doaj   +1 more source

The Economic and Budgetary Effects of Producing Oil and Natural Gas From Shale [PDF]

, 2014
[Excerpt] Recent advances in combining two drilling techniques, hydraulic fracturing and horizontal drilling, have allowed access to large deposits of shale resources—that is, crude oil and natural gas trapped in shale and certain other dense rock ...
Congressional Budget Office
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimization of CO2 EOR and geological sequestration in high-water cut oil reservoirs

Journal of Petroleum Exploration and Production Technology
In terms of the collaborative optimization of CO2 flooding for Enhanced Oil Recovery (EOR) and CO2 sequestration, previous studies have co-optimized both cumulative oil production and CO2 sequestration by various algorithms. However, these solutions fail
Jia Liu, Fankun Meng, Hui Zhao, Yunfeng Xu, Kai Wang, Chenyang Shi, Zifeng Chen   +6 more
doaj   +1 more source

CONTRIBUTION TO THE GEOLOGICAL AND PETROLEUM STUDY OF THE WEST-CONGOLIAN BASIN – CASE OF CARBONATES IN THE KITOBOLA REGION IN CENTRAL CONGO, D.R. CONGO [PDF]

Romanian Journal of Petroleum & Gas Technology
Previous studies carried out in the West-Congolian basin have highlighted potential formations that could play a major role in a petroleum system. In order to complete and enrich the geological and petroleum dossier of the said basin, a field trip to the
Ravely Nsieto Lusakueno, Saint Bob Nsasa Bazona, César Tambashie Okitafumba, Gardiner Samba Vanga, Grace Tshimanga Kamba, Anselme Mavambou Mbadou   +5 more
doaj   +1 more source

Cementing Quality Prediction in the Shunbei Block Based on Genetic Algorithm and Support Vector Regression

Applied Sciences, 2023
There are a number of factors that can affect the quality of cementing, and they constrain each other. Current cementing quality prediction methods are still in the stage of development, and it is difficult to establish an analytical model for cementing ...
Juntao Wei, Shuangjin Zheng, Jiafan Han, Kai Bai   +3 more
doaj   +1 more source

A bridge to a low carbon future? Modelling the long-term global potential of natural gas [PDF]

, 2014
This project uses the global TIMES Integrated Assessment Model in UCL (‘TIAM-UCL’) to provide robust quantitative insights into the future of natural gas in the energy system and in particular whether or not gas has the potential to act as a ‘bridge’ to ...
Anandrajah, Gabrial, Bradshaw, Mike, Ekins, Paul, McGlade, Christophe, Watson, Jim   +4 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source