Results 41 to 50 of about 465,961 (285)

The electronic properties of doped single walled carbon nanotubes and carbon nanotube sensors [PDF]

open access: yes, 2014
We present ab initio calculations on the band structure and density of states of single wall semiconducting carbon nanotubes with high degrees (up to 25%) of B, Si and N substitution. The doping process consists of two phases: different carbon nanotubes (
Tetik, E.
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

InN Based Water Condensation Sensors on Glass and Flexible Plastic Substrates

open access: yesSensors, 2013
In this paper, we report the realization and characterization of a condensation sensor based on indium nitride (InN) layers deposited by magnetron sputtering on glass and flexible plastic substrates, having fast response and using potentially low cost ...
Viorel Dumitru   +7 more
doaj   +1 more source

A Remotely Controlled Calibrator for Chemical Pollutant Measuring-Units [PDF]

open access: yes, 2007
The increasing diffusion of pollutant measuring units, which are installed over wide areas, along with the short calibration interval of several sensors for pollutant quantities, requires new calibration infrastructures to be developed.
Carullo, Alessio   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

π‐Bridged Dimer Strategy of Aggregation‐Induced Emission Molecules to Achieve Very Strong Absorption Ability

open access: yesAggregate
Aggregation‐induced emission (AIE) molecules have attracted widespread attention due to their remarkable fluorescence properties in the aggregated state.
Liwei Dou   +5 more
doaj   +1 more source

Highly Sensitive and Stable Multifunctional Self-Powered Triboelectric Sensor Utilizing Mo2CTx/PDMS Composite Film for Pressure Sensing and Non-Contact Sensing

open access: yesNanomaterials
Sensors based on triboelectric nanogenerators (TENGs) are increasingly gaining attention because of their self-powered capabilities and excellent sensing performance.
Jialiang Fan   +4 more
doaj   +1 more source

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