Results 31 to 40 of about 1,499,389 (281)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Competition between Vortex Unbinding and Tunneling in an Optical Lattice
, 2007 We study a system of two-dimensional Bose gases trapped in minima of a deep one-dimensional optical lattice potential. Increasing the tunneling amplitude between adjacent gases drives a deconfinement transition to a phase where coherence is established ...
A. Iucci +8 more
core +3 more sources
Morphology Behavior of Polysulfone Membranes Made from Sustainable Solvents
GasesIn a previous study, we demonstrated a change in membrane morphology and gas separation performance by varying the recipe of a casting solution based on polysulfone in a certain solvent system.
Steven Kluge +2 more
doaj +1 more source
Competition between paramagnetism and diamagnetism in charged Fermi gases
, 2010 The charged Fermi gas with a small Lande-factor $g$ is expected to be diamagnetic, while that with a larger $g$ could be paramagnetic. We calculate the critical value of the $g$-factor which separates the dia- and para-magnetic regions. In the weak-field
Ashhab +18 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
GasesClimate projects can become one of the key tools for decarbonization in Russia. They have powerful potential in terms of solving the problems of reducing emissions and increasing the absorption of greenhouse gases, as well as monetization potential for ...
Tatiana Nevzorova
doaj +1 more source
Gases, 2023 Hydrogen has become the most promising energy carrier for the future. The spotlight is now on green hydrogen, produced with water electrolysis powered exclusively by renewable energy sources.
Jose M. Marín Arcos, Diogo M. F. Santos
doaj +1 more source
Ultracold dipolar gases - a challenge for experiments and theory
, 2002 We present a review of recent results concerning the physics of ultracold trapped dipolar gases. In particular, we discuss the Bose-Einstein condensation for dipolar Bose gases and the BCS transition for dipolar Fermi gases.
K. G?ral +5 more
core +1 more source