Results 181 to 190 of about 81,325 (286)

Efficacy and Safety of Endoscopic Ultrasound‐Guided Biliary Drainage in the Management of Malignant Hilar Biliary Obstruction: A Multicenter Retrospective Cohort Study

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Malignant hilar biliary obstruction (MHBO) remains challenging for biliary decompression. Although endoscopic ultrasound‐guided biliary drainage (EUS‐BD) has emerged as an alternative to endoscopic retrograde cholangiopancreatography‐guided BD (ERCP‐BD), evidence regarding EUS‐BD for MHBO is limited. Aims To evaluate the efficacy and safety of
Takuji Iwashita   +12 more
wiley   +1 more source

Vitamin Insufficiency After Esophagogastric Surgery and Targeted Supplementation: A Multicenter Prospective Intervention Study Named the VITAMIN Study. [PDF]

open access: yesNutrients
van der Velden AL   +17 more
europepmc   +1 more source

Circulating Plasma Adiposomes as a Partial Lipidomic Readout of Matched Subcutaneous Adipose Tissue: Implications for Interorgan Communication

open access: yesComprehensive Physiology, Volume 16, Issue 6, December 2026.
In 22 participants, circulating plasma adiposome lipidomes showed moderate global concordance with matched subcutaneous adipose tissue adiposomes across 773 lipid features and 18 classes. These findings support plasma adiposomes as accessible, non‐invasive biomarkers of adipose lipid biology while recognizing compartment‐specific differences.
Mohamed Saad Rakab   +9 more
wiley   +1 more source

Association Between Cholecystectomy and Gastroesophageal Inflammatory Findings After Sleeve Gastrectomy: Endoscopic and Metabolic Evaluation. [PDF]

open access: yesObes Surg
Guerra Cordeiro G   +5 more
europepmc   +1 more source

Brain and Cardiometabolic Effects of Major Weight Loss in People With Obesity: Preliminary Cohort Findings

open access: yesObesity Science &Practice, Volume 12, Issue 6, December 2026.
ABSTRACT Objective Given the overlap between obesity‐related metabolic and vascular abnormalities and Alzheimer's disease (AD) risk factors, it is critical to determine whether weight loss improves brain and cardiovascular health. This study examined whether ≥ 40% excess‐weight loss is associated with improvements in cardiometabolic risk, brain ...
Naomi L. Gaggi   +13 more
wiley   +1 more source

Liver Fibrosis and IRS1 rs2972146 Are Associated With Weight Loss Response After Metabolic Bariatric Surgery

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11532-11544, December 2026.
ABSTRACT Background and Aims Weight loss after metabolic bariatric surgery (MBS) is heterogeneous, and the contribution of liver histology and genetic susceptibility to insufficient weight loss (IWL) or weight regain (WR) remains unclear. We assessed the prevalence of IWL and WR after MBS and their association with liver histology and metabolic ...
Felice Cinque   +18 more
wiley   +1 more source

MET Expression in Upper Gastrointestinal Adenocarcinoma: Prevalence, Prognostic Impact, and Implications for Anti‐MET Antibody‐Drug Conjugate Therapy

open access: yesInternational Journal of Cancer, Volume 159, Issue 10, Page 2606-2618, 15 November 2026.
ABSTRACT MET is an actionable receptor tyrosine kinase, and MET‐directed antibody–drug conjugates (ADCs) have recently entered clinical practice with FDA approval in non‐small cell lung cancer and are now being evaluated across gastrointestinal malignancies, with patient selection based on MET immunohistochemistry (IHC) 3+ membranous staining at ...
Tillmann Bedau   +7 more
wiley   +1 more source

Sex‐Specific Proteomic Profiling Identifies Pregnancy Zone Protein as a Complement‐Linked Marker of Adverse Prognosis in Esophageal Adenocarcinoma

open access: yesInternational Journal of Cancer, Volume 159, Issue 10, Page 2595-2605, 15 November 2026.
ABSTRACT Esophageal adenocarcinoma (EAC) exhibits marked male predominance with male‐to‐female ratios reaching 8.5:1, yet the molecular basis underlying this sex disparity remains poorly characterized. We analyzed 92 EAC specimens using mass spectrometry–based proteomics, comprising 47 female and 45 male tumors from treatment‐naïve patients ...
Alexander Quaas   +8 more
wiley   +1 more source

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