Results 131 to 140 of about 5,068 (260)

The role of p38 MAPK in acteoside-mediated gastric ulcer protection. [PDF]

Int J Med Sci
Chen YT, Lin YJ, Tsai CH, Lu YC.
europepmc   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Lacticaseibacillus rhamnosus WH.FH-19: Probiotic Traits, Fermentation Performance, and Potential for Functional Fermented Milk Production. [PDF]

Foods
Sun S, Feng L, Sun L, Zhu X, Zhou M, Li X, Mu G.   +6 more
europepmc   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

Advanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto, Emily Tsang, Marie Karen Tracy Hong Lin, Luca Mannino, Kurt V. Gothelf, Anja Boisen   +5 more
wiley   +1 more source

<i>Prunus mume</i> Concentrate and Ca²⁺ Dual Cross-Linking Facilitate Sodium Alginate/Carboxymethyl Chitosan/Gelatin Microcapsules for Probiotic Encapsulation. [PDF]

Int J Mol Sci
Miao T, An N, Wang H, Zhang C, Rui X, Zhang Q, Xu X.   +6 more
europepmc   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

Gastric juice acidity determination and Tap water hardness determination [PDF]

, 2017
Makarov, Volodymyr, Andreeva, Svetlana, Zavada, Oksana, Vodolazhenko, Mariia, Lukianova, Larysa, Syrovaya, Anna, Tishakova, Tatyana, Petyunina, Valentina, Chalenko, Natalia, Kopoteva, Natalia, Levashova, Olga, Kalinenko, Olga, Savelieva, Elena, Kozub, Svitlana   +13 more
core  

Effect of fermented dairy products on physicochemical and probiotic properties of tarhana in an in vitro gastrointestinal system. [PDF]

J Food Sci Technol
İnce-Palamutoğlu M, Palamutoğlu R, Oruçoğlu B, Kasnak C, Yılmaz S.   +4 more
europepmc   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Comparative Study of Sulfated Polysaccharides From Ulva Lactuca Grown in Tunisia and Morocco: in Vitro Antioxidant Activity and in Vivo Anti-Inflammatory and Anti-Ulcer Effects. [PDF]

Chem Biodivers
Kharrat N, Touhamia Y, Abdallah Kolsi RB, Hamden K, Said RB, Lahcen TOB, Salah HB, Allouche N.   +7 more
europepmc   +1 more source