Determination of Urinary 5-Hydroxyindoleacetic Acid as a Metabolomics in Gastric Cancer
Journal of Gastrointestinal Cancer, 2015The aim of this paper is to study urinary5-hydroxyindoleacetic acid (5-HIAA) in gastric cancer patients with a biochemical method and compare this metabolite with normal control and individuals with chronic gastritis.The subjects were 48 histologically proven gastric adenocarcinoma patients.
Ali Ghasemi, Maral Mokhtari, Amin Rezaei
openaire +3 more sources
Acetic acid chromoendoscopy for determining the extent of gastric intestinal metaplasia
Gastrointestinal Endoscopy, 2017The diagnosis of gastric intestinal metaplasia (IM) is currently performed by histologic assessment of multiple endoscopic biopsies, methylene blue chromoendoscopy, or narrow-band imaging with magnification. However, practical and readily available methods are lacking.
Kyung Ho Song+10 more
openaire +3 more sources
Intramucosal gastric acid concentration determined by glass microelectrode technique
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1973Abstract Penetrations of rat gastric mucosa with Pyrex or H + -sensitive glass microelectrodes in vivo disclosed: (I) The potential difference within the mucosa is negative relative to serosa, the greatest values encountered in the mid-glandular zone; (2) regions of high acidity (H + activity to 170 mequiv/l) were encountered throughout the mucosa;
Carlton R. Caflisch+3 more
openaire +3 more sources
SIMULTANEOUS DETERMINATIONS OF GASTRIC ACIDITY AND THE ALKALINE TIDE IN URINE
Archives of Internal Medicine, 1925In the preceding paper, it has been shown that an alkaline tide can be demonstrated in most cases in which hydrochloric acid is secreted by the stomach, but is not present in cases of achlorhydria or in subjects who secrete very little acid. The present paper is a brief report of a few experiments made to determine how much acid the stomach must ...
Ellery G. Allen, Roger S. Hubbard
openaire +2 more sources
Determination of the time of onset of action of ranitidine and famotidine on intra‐gastric acidity
Alimentary Pharmacology & Therapeutics, 2002SummaryBackground : No standard methods exist for determining the onset of action of gastric antisecretory agents in human subjects.Methods : Intragastric pH was measured when placebo, ranitidine 150 mg, ranitidine 75 mg or famotidine 10 mg were administered 30 min after the end of a meal.Results : When the onset of action was defined as the earliest ...
Malcolm Robinson+3 more
openaire +2 more sources
Ion Exchange Resin Dye Compounds for Use in Indirect Determination of Gastric Acidity
Journal of the American Pharmaceutical Association (Scientific ed.), 1956Abstract The results of a systematic in vitro investigation of the ion exchange resin dye com-pounds are reported. The indicators were selected for their readily recognizable colors. Representative combinations of resins and indicators were prepared and evaluated. A typical procedure for 1 of 21 compounds prepared is presented.
George S. Sharp+2 more
openaire +3 more sources
Voltammetric determination of 5-hydroxydole-3-acetic acid in human gastric juice
Talanta, 2000A method for the determination of the major serotonin metabolite--5-hydroxyindole-3-acetic acid (5-HIAA) in human gastric juice by cyclic voltammetry was described. The measurement conditions were investigated. The potential window was chosen from +0.1 to +0.9 V, the supporting electrolyte was 0.025 M PBS solution (pH 2.0).
Liu, Y.+6 more
openaire +3 more sources
Fatty acid chain length determines cholecystokinin secretion and effect on human gastric motility
Gastroenterology, 1999Fatty acids induce cholecystokinin (CCK) secretion and modify gastric motility, but the chain length requirements for these effects are not known. Nor is it clear whether the effects of fatty acids on gastric motility in humans are CCK mediated or directly exerted.
McLaughlin, J.+5 more
openaire +4 more sources
Studies on acid protease fractions and gastric mucosal atrophy
Gastroenterologia Japonica, 1980The relationships of two acid protease groups, alkali labile pepsin (ALP) and alkali stable pepsin (ASP), and gastric mucosal atrophy, were studied. ALP and ASP were determined separately by alkali treatment. The extent of fundic gland atrophy was detected by endoscopic congo red test.
openaire +3 more sources
1. A dose-response curve for histamine phosphate after 2 hr. in the male Sprague-Dawley pylorus-ligated rat is presented. 2. Peak response in both acid output and gastric juice volume occurred with the subcutaneous administration of histamine in a dose of 50 mg./kg. 3.
Jeremy H. Thompson, Yien Hwei Lee
openaire +2 more sources