Results 161 to 170 of about 15,195 (301)

Gastroprotective, Antioxidant, Anti-Inflammatory, and Toxicological Evaluation of Stem Bark Extracts of <i>Vitellaria paradoxa</i> and <i>Parkia biglobosa</i>. [PDF]

Pharmaceuticals (Basel)
Dangnon B, Dah-Nouvlessounon D, Hoteyi SMI, Sina H, Tomescu JA, Akpo KJ, Sangare-Oumar MM, Adjanohoun A, Babalola OO, Vamanu E, Baba-Moussa L.   +10 more
europepmc   +1 more source

Evaluation of acute toxicity and gastroprotective activity of BI. rhizome against ethanol-induced gastric mucosal injury in rats [PDF]

core   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Acute Toxicity Assessment, In Vitro Antacid and Cytoprotective Effects of Root Bark Aqueous Extract of <i>Diospyros mespiliformis</i> on Water Immersion Stress-Induced Gastric Ulcers in Rats. [PDF]

Can J Gastroenterol Hepatol
Vandi VL, Amang AP, Christophe Mezui, Tchokomeni Siwe G, Baponwa O, Aboubakar S, Emakoua JF, Tan PV.   +7 more
europepmc   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Gastrointestinal tolerance to a standardized milk-based hydration strategy is similar across exercise modalities. [PDF]

Front Nutr
Garzón-Mosquera JC, Portuguez-Molina P, Aragón Vargas LF.   +2 more
europepmc   +1 more source

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Acidic Tumor Microenvironments and Emerging Therapeutic Strategies for Cancer Therapy. [PDF]

Yonsei Med J
Zhuang Y, Tong L, Sun X.
europepmc   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Characterization of gastric ulcer influenced by hot-humid environment and high-sugar and high-fat diet provides a further insight into its underlying mechanism. [PDF]

Sci Rep
Zhang T, Cao M, Zhang R, Ding L, Qiu F.
europepmc   +1 more source