Results 91 to 100 of about 110,227 (357)

The life expectancy of patients with metabolic syndrome after weight loss: study protocol for a randomized clinical trial (LIFEXPE-RT)

Trials, 2019
Background To date, surgeons and physicians have found positive results treating metabolic syndrome with surgical and non-surgical weight loss therapies.
Oral Ospanov, Galymzhan Yeleuov, Irina Kadyrova, Farida Bekmurzinova   +3 more
doaj   +1 more source

Inhibition of food intake in obese subjects by peptide YY3-36 [PDF]

, 2003
Background: The gut hormone fragment peptide YY3-36 (PYY) reduces appetite and food intake when infused into subjects of normal weight. In common with the adipocyte hormone leptin, PYY reduces food intake by modulating appetite circuits in the ...
Batterham, RL, Bloom, SR, Cohen, MA, Ellis, SM, Frost, GS, Ghatei, MA, Le Roux, CW, Withers, DJ   +7 more
core   +1 more source

Noni (Morinda citrifolia) Seed Oil: Phytochemical Composition, Bioactivity, and Emerging Applications in Food and Health

Food Chemistry International, EarlyView.
Noni seed oil from Morinda citrifolia, highlighting its bioactive composition, conventional and green extraction methods, and major stability challenges. Encapsulation strategies improve oxidative stability and bioavailability, along with potential applications in functional foods and cosmetics, and key barriers to large‐scale commercialization ...
Sumidha Palanisamy, Kanimozhi Viswanathan, Pavithra Radhakrishnan, Sonali Lini, Sukumar Muthusamy   +4 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling for Predicting Drug Levels After Bariatric Surgery: Vardenafil Exposure Before vs. After Gastric Sleeve/Bypass

Biomolecules
Bariatric surgery involves major changes in the anatomy and physiology of the gastrointestinal tract, which may alter oral drug bioavailability and efficacy. Phosphodiesterase-5 inhibitor (PDE5i) drugs are the first-line treatment of erectile dysfunction,
Daniel Porat, Oleg Dukhno, Sandra Cvijić, Arik Dahan   +3 more
doaj   +1 more source

Living at genetic risk: The patient experience of Lynch syndrome

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome is a germline cancer predisposition syndrome caused by a variant in one of four genes. Lynch syndrome places individuals at significantly higher risk for a range of cancers, especially colorectal and endometrial. Depending on which gene is affected, the risk of ovarian, gastric, small bowel, pancreatic, biliary urothelial, brain,
Nicola Reents, Georgina Hoffmann, Kelly Kohut   +2 more
wiley   +1 more source

MODIFIED METHOD OF LAPAROSCOPIC GASTRIC BYPASS SURGERY

Вестник хирургии имени И.И. Грекова, 2017
OBJECTIVE. The study aimed to improve the results of gastric bypass surgery. MATERIALS AND METHODS. The article analyzed the results of surgical treatment of 342 patients with metabolic syndrome who underwent operation at the period from 2008 to 2016.The
M. B. Fishman
doaj   +1 more source

Improvements in diabetic albuminuria and podocyte differentiation following Roux-en-Y gastric bypass surgery

Diabetes & Vascular Disease Research, 2020
Background: Multiple studies demonstrate an albuminuria-lowering impact of Roux-en-Y gastric bypass surgery, but neither evaluation of its penetrance across different baseline levels of albuminuria nor its association with alterations in podocyte ...
Aoife L Canney, Ricardo V Cohen, Jessie A Elliott, Cristina M Aboud, William P Martin, Neil G Docherty, Carel W le Roux   +6 more
doaj   +1 more source

Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome [PDF]

, 2016
© 2016 John Wiley & Sons Ltd Context: Animal studies suggest that cannabinoid receptor-1 (CB-1) blockade reduces inflammation and neovascularization by decreasing vascular endothelial growth factor (VEGF) levels associated with a reduction in ...
Atkin, Stephen L., Coady, Anne-Marie, Javed, Zeeshan, Kilpatrick, Eric S., Sathyapalan, Thozhukat   +4 more
core   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

European Guidelines for Obesity Management in Adults [PDF]

, 2015
Obesity is a chronic metabolic disease characterised by an increase of body fat stores. It is a gateway to ill health, and it has become one of the leading causes of disability and death, affecting not only adults but also children and adolescents ...
Busetto, Luca, Fried, Martin, Micic, Dragan, Schindler, Karin, Toplak, Hermann, Tsigos, Constantine, Yumuk, Volkan   +6 more
core   +2 more sources