Results 71 to 80 of about 54,066 (313)

Marcadores pró-inflamatórios e de estresse oxidativo em pacientes submetidos à gastroplastia com bypass em y de Roux [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pos-Graduação em Nutrição, Florianópolis, 2009.Obesity is an inflammatory condition associated to oxidative stress.
Silva, Viviane Rodrigues Gonçalves da
core  

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao, Jean G. Malavé, Joseph S. Rossi, Francesco Franchi, Ellen C. Keeley, Dominick J. Angiolillo, George A. Stouffer, Larisa H. Cavallari, Craig R. Lee   +8 more
wiley   +1 more source

Efeitos da cirurgia bariátrica no estresse oxidativo [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2010Introdução: Obesidade é uma doença crônica associada ao estresse oxidativo. A cirurgia bariátrica pode
Dadalt, Carla
core  

Application of Virtual Twin PBPK Models in Individuals with Obesity via CYP3A4 Phenotyping Using Endogenous Biomarker Data

Clinical Pharmacology &Therapeutics, EarlyView.
Plasma 4β‐hydroxycholesterol (4β‐OHC) normalized for the levels of its parent cholesterol (4β‐OHC/C) is an endogenous biomarker for hepatic CYP3A4. This study evaluated CYP3A4 activity longitudinally in individuals while their obesity status was changing. 4β‐OHC/C was measured pre‐surgery (n = 54) and 2 years after Roux‐en‐Y gastric bypass (n = 30) and
Nihan Izat, Haribhau Kangne, Rasmus Jansson‐Löfmark, Jens K. Hertel, Amin Rostami‐Hodjegan, Ida Robertsen, Aleksandra Galetin   +6 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling for Predicting Drug Levels After Bariatric Surgery: Vardenafil Exposure Before vs. After Gastric Sleeve/Bypass

Biomolecules
Bariatric surgery involves major changes in the anatomy and physiology of the gastrointestinal tract, which may alter oral drug bioavailability and efficacy. Phosphodiesterase-5 inhibitor (PDE5i) drugs are the first-line treatment of erectile dysfunction,
Daniel Porat, Oleg Dukhno, Sandra Cvijić, Arik Dahan   +3 more
doaj   +1 more source

Measurement of hepatic insulin sensitivity early after the bypass of the proximal small bowel in humans

Obesity Science & Practice, 2017
Summary Objective Unlike gastric banding or sleeve gastrectomy procedures, intestinal bypass procedures, Roux‐en‐Y gastric bypass in particular, lead to rapid improvements in glycaemia early after surgery.
A. D. Miras, R. Herring, A. Vusirikala, F. Shojaee‐Moradi, N. C. Jackson, S. Chandaria, S. N. Jackson, A. P. Goldstone, N. Hakim, A. G. Patel, A. M. Umpleby, C. W. Le Roux   +11 more
doaj   +1 more source

The life expectancy of patients with metabolic syndrome after weight loss: study protocol for a randomized clinical trial (LIFEXPE-RT)

Trials, 2019
Background To date, surgeons and physicians have found positive results treating metabolic syndrome with surgical and non-surgical weight loss therapies.
Oral Ospanov, Galymzhan Yeleuov, Irina Kadyrova, Farida Bekmurzinova   +3 more
doaj   +1 more source

Overview of gastric bypass surgery

, 2016
Gastric bypass surgery is indicated for several clinical reasons including benign and malignant upper gastrointestinal tract pathologies. Any gastric resection or bypass procedure interferes with gastric emptying and the aim of reconstruction is to ...
Weledji, Elroy Patrick
core   +1 more source

Glucose and Loss of Control Eating: Evidence From Naturalistic Assessment After Roux‐en‐Y Gastric Bypass

European Eating Disorders Review, EarlyView.
ABSTRACT Objective While loss of control (LOC) eating is associated with poor outcomes following metabolic and bariatric surgery (MBS), the mechanisms driving it are less understood. This study used momentary, naturalistic data to examine glucose as a biological correlate of LOC eating after Roux‐en‐Y gastric bypass (RYGB).
Gail A. Kerver, Kristine J. Steffen, Debra L. Safer, Glen Forester, David B. Sarwer, Stephen A. Wonderlich, Scott G. Engel   +6 more
wiley   +1 more source

Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss in Patients With Morbid Obesity [PDF]

, 2018
Importance Sleeve gastrectomy is increasingly used in the treatment of morbid obesity, but its long-term outcome vs the standard Roux-en-Y gastric bypass procedure is unknown.
Yves Borbély, Borbély, Yves, Bueter, Marco; https://orcid.org/, Ralph Peterli, Dino Kröll, Bueter, Marco, Drewe, Jürgen, Nett, Philipp, Beglinger, Christoph, Schultes, Bernd, Bettina Karin Wölnerhanssen, Bernd Schultes, Nett, Philipp C., Marco Bueter, Wölnerhanssen, Bettina Karin, Philipp Nett, Marc Schiesser, Peters, Thomas, Schiesser, Marc, Diana Vetter, Christoph Beglinger, Borbély, Yves Michael, Kröll, Dino, Vetter, Diana, Jürgen Drewe, Thomas Peters, Peterli, Ralph   +26 more
core   +1 more source