Results 141 to 150 of about 5,337,491 (425)

Microsatellite Instability Is Associated with the Clinicopathologic Features of Gastric Cancer in Sporadic Gastric Cancer Patients [PDF]

, 2010
Purpose: Replication error is an important mechanism in carcinogenesis. The microsatellite instability (MSI-H) of colorectal cancers is associated with the development of multiple cancers.
Ahn, Bae, Bae, Boland, Chong, Cleary, Hayden, Honmyo, Japanese Gastric Cancer Association, Kaibara, Kim, Kodera, Lauren, Lim, Lynch, Miyoshi, Nakashima, Oliveira, Pedroni, Ribeiro, Sengupta, Sepulveda, Suraweera, Tahara   +23 more
core   +3 more sources

Molecular Mechanism of Helicobacter pylori-Induced Gastric Cancer

Journal of Gastrointestinal Cancer, 2020
Introduction Various types of cancers threaten human life. The role of bacteria in causing cancer is controversial, but it has been determined that the Helicobacter pylori infection is one of the identified risk factors for gastric cancer.
M. Alipour
semanticscholar   +1 more source

Gastric Cancer [PDF]

Journal of the National Comprehensive Cancer Network, 2010
Gastric cancer is rampant in several countries around the world. Its incidence in the West has been on the decline for more than 40 years; however, the location of gastric cancer has shifted proximally in the past 15 years. The reason for this shift is not clear. Diffuse histology is also more common now than intestinal type of histology. Advances have
Mary Kay Washington, James Posey, Stephen Shibata, James S. Barthel, Tanios Bekaii-Saab, James A. Hayman, Raymond U. Osarogiagbon, Prajnan Das, Vivian E. Strong, Lawrence Kleinberg, Christopher G. Willett, Wayne L. Hofstetter, Michael Korn, Douglas E. Wood, Rajesh N. Keswani, Mary F. Mulcahy, Charles S. Fuchs, David H. Ilson, Kenneth L. Meredith, Gary Y. Yang, Thomas A. D'Amico, Crystal Denlinger, Mark B. Orringer, Hans Gerdes, Walter J. Scott, Aaron R. Sasson, David J. Bentrem, Cameron D. Wright, Jaffer A. Ajani, Lisa Hazard   +29 more
openaire   +3 more sources

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Antigen-presenting cancer associated fibroblasts enhance antitumor immunity and predict immunotherapy response

Nature Communications
Cancer-associated fibroblasts (CAF) play a crucial role in tumor progression and immune regulation. However, the functional heterogeneity of CAFs remains unclear. Here, we identify antigen-presenting CAFs (apCAF), characterized by high MHC II expression,
Junquan Song, Rongyuan Wei, Chenchen Liu, Zhenxiong Zhao, Xuanjun Liu, Yanong Wang, Fenglin Liu, Xiaowen Liu   +7 more
doaj   +1 more source

Treatment of gastric cancer cells with non-thermal atmospheric plasma generated in water [PDF]

arXiv, 2016
Non-thermal atmospheric plasma (NTAP) can be applied to living tissues and cells as a novel technology for cancer therapy. Even though studies report on the successful use of NTAP to directly irradiate cancer cells, this technology can cause cell death only in the upper 3-5 cell layers.
arxiv  

propnet: Propagating 2D Annotation to 3D Segmentation for Gastric Tumors on CT Scans [PDF]

arXiv, 2023
**Background:** Accurate 3D CT scan segmentation of gastric tumors is pivotal for diagnosis and treatment. The challenges lie in the irregular shapes, blurred boundaries of tumors, and the inefficiency of existing methods. **Purpose:** We conducted a study to introduce a model, utilizing human-guided knowledge and unique modules, to address the ...
arxiv  

Guidelines for endoscopic diagnosis of early gastric cancer

Digestive Endoscopy, 2020
The Japan Gastroenterological Endoscopy Society developed the Guideline for Endoscopic Diagnosis of Early Gastric Cancer based on scientific methods. Endoscopy for the diagnosis of early gastric cancer has been acknowledged as a useful and highly precise
K. Yao, N. Uedo, T. Kamada, T. Hirasawa, T. Nagahama, S. Yoshinaga, M. Oka, Kazuhiko Inoue, K. Mabe, T. Yao, Masahiro Yoshida, I. Miyashiro, K. Fujimoto, H. Tajiri   +13 more
semanticscholar   +1 more source

Diet and gastric cancer [PDF]

Vojnosanitetski pregled, 2003
The aim of this case-control study, conducted in Serbia during the period 1998-2000, was to investigate whether diet was associated with the development of gastric cancer. The case group consisted of 131 patients with histologically confirmed gastric cancer, and the control group of 131 patients with orthopedics diseases and injuries.
Sandra Sipetic, Sladjana Tomic-Kundakovic, Hristina Vlajinac, Slavenka Jankovic, Jelena Marinkovic, Jadranka Maksimovic   +5 more
openaire   +3 more sources

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source