Results 181 to 190 of about 445,656 (308)

Novel Quaternary Ammonium Salt‐Linked STING Agonist Antibody‐Drug Conjugate: Synergistic Activation of Tumor Immunity with Mitigated Off‐Target Toxicity

Advanced Science, EarlyView.
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long, Borui Tang, Fei Xie, Lianqi Liu, Yangyihua Zhou, Jingwen Dong, Jianfeng Wang, Cuicui Sun, Yuting Wang, Ruoqi Li, Na Zhang, Liping Li, Longlong Luo, Junhai Xiao, Wu Zhong, Dian Xiao, Hongbin Deng, Xinbo Zhou   +17 more
wiley   +1 more source

Gastric cancer in children infected with <i>Helicobacter pylori</i>. [PDF]

World J Gastrointest Oncol
Gong X, Chen C, Shen JF.
europepmc   +1 more source

Age Differences in the Histology and Growth Pattern of the Gastric Cancer

, 1968
Kaoru Miura
openalex   +2 more sources

Targeted Dual‐Responsive Liposomes Co‐Deliver Jolkinolide B and Ce6 to Synergistically Enhance the Photodynamic/Immunotherapy Efficacy in Gastric Cancer through the PANoptosis Pathway

Advanced Science, EarlyView.
Schematic model of CJP–TiN liposomes for gastric cancer (GC) treatment. Internalizing RGD peptide (iRGD) targets tumor cells, while Chlorin e6 (Ce6) generates reactive oxygen species (ROS). Jolkinolide B (JB) activates the PANoptosis pathway via caspase‐8, enhancing GC cell death and immune response, transforming “cold tumors” into “hot tumors” by ...
Chenhui Ma, Lei Gao, Kewei Song, Baohong Gu, Bofang Wang, Yang Yu, Xueyan Wang, Xuemei Li, Jike Hu, Weigao Pu, Yunpeng Wang, Na Wang, Dedai Lu, Zhijian Han, Hao Chen   +14 more
wiley   +1 more source

A Histochemical Study on The Human Gastric Mucosa and Gastric Cancer

, 1963
Motoo KITAMURA
openalex   +4 more sources

Advances in the Study of Metabolic Reprogramming in Gastric Cancer. [PDF]

Cancer Med
Rong Y, Teng Y, Zhou X.
europepmc   +1 more source

Histochemical Studies of Hydrolytic Enzymes and Dehydrogenases in the Human Gastric Cancers

, 1967
Kisaburo Takeuchi
openalex   +2 more sources

Abnormal β‐Hydroxybutyrylation Modification of ARG1 Drives Reprogramming of Arginine Metabolism to Promote the Progression of Colorectal Cancer

Advanced Science, EarlyView.
Alterations in arginine metabolism and β‐hydroxybutyrylation (Kbhb) modifications play a critical role in tumor progression. This study reveals valuable insights into arginine metabolism reprogramming involving the ARG1‐Kbhb/P300/SLC3A2 signaling axis and uncovers an effective therapy combining BHB with ARG1 inhibitor through conventional enzymatic and
Chuman Lin, Zhiyang Li, Xiaotong Zhu, Wanbing Zhou, Xiansheng Lu, Jiali Zheng, Jie Lin   +6 more
wiley   +1 more source

GNGT1 is a potential prognostic and immunologic biomarker in gastric cancer. [PDF]

Sci Rep
Huang X, Lin J, Wang J, Yang W, Ou W, Huang X, Chen J, Zhang Z, Wu X.   +8 more
europepmc   +1 more source

Cancer Development in Gastric Stump After Partial Gastrectomy for Peptic Ulcer

, 1962
K Liavaag
openalex   +2 more sources