Results 21 to 30 of about 762,599 (262)

Two distinct aetiologies of cardia cancer, evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status [PDF]

, 2007
Background: Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear.
Aase, S., Derakhshan, M.H., Fyfe, V., Hansen, S., Jellum, E., McColl, K.E.L., Melby, K.K., Vollset, S.E.   +7 more
core   +2 more sources

The prognostic impact of EGFR, ErbB2 and MET gene amplification in human gastric carcinomas as measured by quantitative Real-Time PCR [PDF]

, 2015
Purpose: Identification of critical genes which play pivotal roles in controlling tumor growth and survival will establish the basis for developing therapeutic targets. In this study, we focused on frequencies of EGFR, ErbB2 and MET gene amplification in
Farazmandfar, T., Janbabai, G., Naghshvar, F., Oladi, Z., Taghvaei, T.   +4 more
core   +1 more source

The esophagogastric junctional adenocarcinoma an increasing disease [PDF]

, 2017
Identifying and defining the esophagogastric junctional adenocarcinoma (EGJA) as an independent disease apart from gastric cancer (GC) and esophagus cancer (EG) it has always been a difficult issue entailing doubts about the appropriate therapeutic ...
Andreetti, Claudio, Ibrahim, Mohsen, Menna, Cecilia, Pastina, Monica   +3 more
core   +1 more source

Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]

, 2008
<b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Derakhshan, M.H., Didevar, R., Fyfe, V., Kazemi, A., Malekzadeh, R., McColl, K.E.L., Rakhshani, N., Sotoudeh, M., Watabe, H., Yazdanbod, A., Zolfeghari, A.   +10 more
core   +1 more source

Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts [PDF]

, 2001
BACKGROUND: The magnitude of the association between Helicobacter pylori and incidence of gastric cancer is unclear. H pylori infection and the circulating antibody response can be lost with development of cancer; thus retrospective studies are ...
Aase, S., Aromaa, A., Berglund, G., Blaser, M.J., Chen, C.J., Dawsey, S.M., Floren, C.H., Forman, D., Forsgren, A., Friedman, G.D., Hansen, S., Heinonen, O.P., Jellum, E., Knekt, P., Kosunen, T.U., Kurata, J.H., Law, M., Limberg, P.J., Lin, J.T., Mark, S.D., Melby, K.K., Nomura, A., Ozasa, K., Parsonnet, J., Qiao, Y.L., Ross, R., Siman, J.H., Stemmermann, G.N., Taylor, P.R., Tulinius, H., Varghese, C., Virtamo, J., Vollset, S.E., Wald, N.J., Watanabe, Y., Webb, P.M., Yu, M., Yuan, J.M.   +37 more
core   +1 more source

Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation [PDF]

, 2013
A role for WNT signalling in gastric carcinogenesis has been suggested due to two major observations. First, patients with germline mutations in adenomatous polyposis coli (APC) are susceptible to stomach polyps and second, in gastric cancer, WNT ...
A Gregorieff, A Horii, A Jung, A Novak, AC de Vries, AN Milne, AT Franco, B Kim, B Tycko, C Cavard, D Athineos, D M Pritchard, DM Parkin, E Half, E Tahara, EF Chan, G Gatta, H Guillen-Ahlers, H Ireland, H Luche, H Nagase, H Oshima, H Shibata, H Watanabe, H Zhang, HC Zheng, HJ Freeman, J Cordero, J Neumann, J Parsonnet, J Woodgett, JG Forte, K Miyazawa, K Oien, KF Becker, KW Kinzler, LK Bianchi, M Crabtree, M Iida, M Nakayama, M Shitashige, M Suzuki, M Suzuki, M Torbenson, MG Smith, MP Ebert, N Barker, N Barker, N Barker, N Barker, N Barker, N Harada, N Murata-Kamiya, N Uemura, O J Sansom, O Sokolova, O Tetsu, OJ Sansom, P Blache, P Correa, P Correa, P Lauren, P Salgueiro, P Soriano, PJ Guilford, R A Ridgway, R Kemp, R Poulsom, S Garrean, S Nakatsuru, S Patel, S Patel, S Radulescu, S Segditsas, S Sekine, SC Abraham, SC Abraham, SM Przemeck, SS Ng, T Gnad, T Oda, TC He, WM Clements, WS Park, XC He, Y Miyoshi, Y Park do, Z Spicer, Z Zhao   +88 more
core   +1 more source

Association of Neuronal Autoantibodies with Overall Survival in Patients with Gastric Cancer. [PDF]

Cancer Res Commun
Liu G, Tan X, Xu K, Liu J, Zheng Q, Huang X, Pan S, Li G, Hu Y, Liu H.   +9 more
europepmc   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Stomach One-Point Cancer: One Case Report and Literature Review [PDF]

, 2009
Gastric cancer is one of the most common cancers and one of themost frequent causes of cancer deaths worldwide. Early detection andaccurate preoperative staging of gastric cancer is essential for planning optimal therapy such as endoscopic mucosal ...
B.Y. Zhao, Chengzhong Xing, G.W. Zhang, H.Y. Chen, Hao Zhang, Huimian Xu, Meixian Wang, P.F. Zhang, Q.X. Chen   +8 more
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source