Results 31 to 40 of about 445,656 (308)

Effect of perioperative blood transfusion on prognosis of patients with gastric cancer: a retrospective analysis of a single center database

open access: yesBMC Cancer, 2018
Background The association between perioperative blood transfusion and the prognosis of patients with gastric cancer is still unclear. Methods A total of 1581 patients with gastric cancer who underwent curative gastrectomy from 2000 to 2008 were ...
Xiaowen Liu   +3 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Prevalence and Implications of Bone Marrow Involvement in Patients with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

open access: yesGut and Liver, 2018
Background/AimsMucosa-associated lymphoid tissue (MALT) lymphoma of the stomach is an uncommon disease. Bone marrow involvement is reported even in patients with only a mucosal lesion.
Sang Il Choi   +9 more
doaj   +1 more source

Nutrition and Gastric Cancer [PDF]

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2000
The reasons for the worldwide decline in stomach cancer incidence and mortality rates are not fully understood, but dietary changes are clearly implicated. While the possible mechanisms of gastric carcinogenesis and the impact of Helicobacter pylori eradication remain open to debate, at least two practical recommendations – to increase fruit and ...
C. La Vecchia, S. Franceschi
openaire   +4 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Acquired diaphragmatic hernia following a peritoneal biopsy for gastric cancer dissemination in the diaphragm: a case report

open access: yesSurgical Case Reports, 2023
Background Acute diaphragmatic hernia is a life-threatening condition caused by prolapse of an abdominal organ into the thoracic cavity through a defect in the diaphragm.
Kazuya Endo   +9 more
doaj   +1 more source

Focus on gastric cancer [PDF]

open access: yesCancer Cell, 2004
Severe dysplasia/noninvasive mucosal carcinoma could contain different entities that have different abilities to invade the lamina propria mucosae. However, key molecular alterations that determine this progression are unknown. The presence of lymph node or distant metastasis is a very important factor in deciding a treatment strategy, but accurate ...
Mitsuru Sasako, Toshikazu Ushijima
openaire   +3 more sources

Treatment of Gastric Cancer [PDF]

open access: yesCancers, 2020
Surgery represents the only method for potentially curative intent for gastric cancer (GC) [...]
Stefano Rausei, Georgios D. Lianos
openaire   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

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