Results 71 to 80 of about 677,058 (306)

Gastric inflammatory myofibroblastic tumor: a case report

Surgical Case Reports
Background Inflammatory myofibroblastic tumor (IMT) of the stomach is an uncommon mesenchymal neoplasm. We present a case of gastric submucosal tumor (SMT) where the final diagnosis was IMT.
Taku Hattori, Yutaka Tanizawa, Tadakazu Shimoda, Yusuke Koseki, Kenichiro Furukawa, Keiichi Fujiya, Daisuke Aizawa, Takashi Sugino, Masanori Terashima, Etsuro Bando   +9 more
doaj   +1 more source

Clinical implications of DLL4 expression in gastric cancer [PDF]

, 2013
BACKGROUND: Delta-like ligand 4 (DLL4)-Notch signaling plays a key role in tumor neovascular development and angiogenesis during tumor growth. The clinical significance of DLL4 expression in gastric cancer has not been clarified.
Akihiro Nakajo, Hiroshi Kurahara, Hiroshi Okumura, Shinichi Ueno, Shoji Natsugoe, Sumiya Ishigami, Takaaki Arigami, Tetsuro Owaki, Tetsuro Setoyama, Yasuto Uchikado, Yoshiaki Kita, Yoshikazu Uenosono, Yuka Nishizono, Yuko Kijima   +13 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Experiences of multidisciplinary gastric cancer treatment at the National Cancer Center, Korea [PDF]

Korean Journal of Clinical Oncology, 2013
Multidisciplinary treatment (MDT) is considered to be beneficial for patients undergoing complex treatments for cancer. The efforts of MDT led to the initiation of nowadays well known trials in gastroesophageal cancer treatment.
Daniel Reim, Bang Wool Eom, Young-Woo Kim   +2 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Avelumab in Gastric Cancer

Immunotherapy, 2019
Gastric cancer (GC) is the fifth most common malignancy and the third cause of cancer-related deaths worldwide. Currently, surgery and chemotherapy remain the main therapeutic options and the prognosis of the disease is still poor in the metastatic setting.
Roviello G., D'Angelo A., Generali D., Pittacolo M., Ganzinelli M., Iezzi G., De Manzini N., Sobhani N.   +7 more
openaire   +6 more sources

Differences in patient-reported symptoms following radical gastrectomy: a propensity score-matched cohort study

Frontiers in Oncology
BackgroundSurgery is not only the mainstay of treatment for gastric cancer but also the key to improving postoperative quality of life for patients. Patient-reported symptoms following radical gastrectomy tend to be diverse and descriptive.
Yuan Xie, Li Li, Rui Xu, Qiong Gu, Shuo-meng Xiao, Hong-Li Ma   +5 more
doaj   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Antigen-presenting cancer associated fibroblasts enhance antitumor immunity and predict immunotherapy response

Nature Communications
Cancer-associated fibroblasts (CAF) play a crucial role in tumor progression and immune regulation. However, the functional heterogeneity of CAFs remains unclear. Here, we identify antigen-presenting CAFs (apCAF), characterized by high MHC II expression,
Junquan Song, Rongyuan Wei, Chenchen Liu, Zhenxiong Zhao, Xuanjun Liu, Yanong Wang, Fenglin Liu, Xiaowen Liu   +7 more
doaj   +1 more source