Results 21 to 30 of about 190,878 (267)

The gastric acid pocket is attenuated in H. pylori infected subjects [PDF]

open access: yes, 2016
Objective Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. Design We studied 31 H.
Ballantyne, Stuart A.   +6 more
core   +1 more source

Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]

open access: yes, 2008
<b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Derakhshan, M.H.   +10 more
core   +1 more source

Protective effect of omeprazole on gastric mucosal of cirrhotic portal hypertension rats [PDF]

open access: yes, 2014
ObjectiveTo observe the protective effect of omeprazole on gastric mucosal of cirrhotic portal hypertension rats.MethodsAll rats were randomly divided into normal control group, cirrhosis and treatment group. Thioacetamide was used to establish rat model
Cai, Chun-Jiang   +7 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

THE GASTRIC MUCOSA IN DELIRIUM TREMENS [PDF]

open access: yesArchives of Internal Medicine, 1916
In the experience of Dr. E. R. Le Count, coroner's physician in Chicago, petechial hemorrhages in the stomach lining are among the most constant lesions found in the bodies of persons dying during the acute delirium of chronic alcoholism. This condition has been considered an acute alcoholic gastritis, but in the absence of any microscopic examination ...
openaire   +3 more sources

Treatment of helicobacter pylori infection in atrophic gastritis [PDF]

open access: yes, 2018
Helicobacter pylori (Hp) is a major human pathogen causing chronic, progressive gastric mucosal damage and is linked to gastric atrophy and cancer. Hp-positive individuals constitute the major reservoir for transmission of infection.
Annibale, B, Carabotti, M, Lahner, E
core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up [PDF]

open access: yes, 2015
Objective. Atrophic gastritis (AG) is a risk condition for gastric cancer and type I gastric carcinoids. Recent studies assessing the overall risk of gastric cancer and carcinoids in AG at long-term follow up are lacking.
Annibale, Bruno   +6 more
core   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

On Sensation to Pain in the Gastric Mucosa [PDF]

open access: yesThe American Journal of the Medical Sciences, 1909
n ...
openaire   +2 more sources

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