Results 51 to 60 of about 224,963 (338)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Indometacin loading and in vitro release properties from novel carbopol coated spherical mesoporous silica nanoparticles [PDF]

, 2013
Spherical MCM-41 silica nanosized particles were synthesized and post synthesis modified by 3-aminopropyltriethoxysilane (APTES) in order to prepare amino-functionalized carrier.
Agnes Szegedi, Basaldella, Borislav Tzankov, Chang, Chen, De Muth, Doadrio, Gao, Georgi Momekov, He, Hong, Horcajada, Huh, Judith Mihály, Kaneko, Konturek, Krassimira Yoncheva, Lai, Lee, Manzano, Manzano, Margarita Popova, Naito, Nicolai Lambov, Ogiso, Popova, Shorrock, Shrivastava, Slowing, Szegedi, Tan, Trewyn, Vallet-Regi, Wang, Wang, Yang, You   +36 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Features of Microcirculatory Disoders in Gastric Mucosa and Duodenal Mucosa in Children with Chronic Gastroduodenitis

Zdorovʹe Rebenka, 2013
The article displays the main histological and immunohistochemical features of microcirculatory disorders in gastric mucosa and duodenal mucosa. The obtained data provide a differentiated approach to the prescription of antisecretory drugs in childhood ...
V.I. Bobrova, O.V. Pyankova, N.І. Nadtochiу, S.S. Voronina, V.V. Zamula   +4 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey. [PDF]

, 2016
BackgroundFirst reported in 1955, Cronkhite-Canada syndrome (CCS), a rare syndrome characterized by ectodermal abnormalities and inflammatory changes of the gastrointestinal tract mucosa, has been associated with a poor prognosis and life-threatening ...
Hibi, Toshifumi, Hirata, Ichiro, Hokari, Ryota, Kaunitz, Jonathan D, Komoto, Shunsuke, Miura, Soichiro, Tanaka, Masanori, Tomita, Kengo, Watanabe, Chikako   +8 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Effect of hydrogen sulfide-releasing aspirin on esophageal and gastric mucosa compromised by stress injury [PDF]

The Ukrainian Biochemical Journal, 2017
Recent data of study H2S in gastrointestinal tract has proven its potent cytoprotection on mucosal defense among acid-related diseases in the gut. The aim was to evaluate the effects of H2S-releasing aspirin derivative (ATB-340) on esophageal and gastric
O. S. Zayachkivska1, N. S. Bula1, Ya. I. Pavlovskiy1, I. O. Pshyk-Titko1, E. M. Gavriluk1, O. I. Grushka1, J. L. Wallace2   +6 more
doaj   +1 more source

Gastric Oxyntic Mucosa Pseudopolyps [PDF]

Clinical Endoscopy, 2021
Dong Chan Joo, Gwang Ha Kim
openaire   +3 more sources