Results 61 to 70 of about 211,995 (354)

The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori [PDF]

, 2012
Helicobacter (H.) suis colonizes the stomach of pigs and is the most prevalent gastric non-H. pylori Helicobacter species in humans. Limited information is available on host immune responses after infection with this agent and it is unknown if variation ...
Ducatelle, Richard, Flahou, Bram, Haesebrouck, Freddy, Pasmans, Frank, Rychlik, Ivan, Smet, Annemieke, Van Deun, Kim, Volf, Jiri   +7 more
core   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

THE INFECTION WITH HELICOBACTER PYLORI FAVORS THE PRESENCE OF GIARDIA LAMBLIA IN THE GASTRIC MUCOSA – CASE PRESENTATION [PDF]

Romanian Journal of Infectious Diseases, 2016
Helicobacter pylori and Giardia lamblia are common worldwide. Helicobacter pylori is a favoring factor for the presence of Giardia lamblia in the stomach due to the neutralization of the gastric pH through the secretion of urease.
Meliț Lorena Elena, Mărginean Cristina Oana, Mocan Simona, Suciu Nicoleta, Mărginean Maria Oana   +4 more
doaj   +1 more source

Infectious aetiology of marginal zone lymphoma and role of anti-infective therapy [PDF]

, 2016
Marginal zone lymphomas have been associated with several infectious agents covering both viral and bacterial pathogens and in some cases a clear aetiological role has been established.
Annechini, Giorgia, D'Elia, Gianna Maria, Perrone, Salvatore, Pulsoni, Alessandro   +3 more
core   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Integrative roles of transforming growth factor-α in the cytoprotection mechanisms of gastric mucosal injury

BMC Gastroenterology, 2006
Background Transforming growth factor α (TGFα) protects against gastric mucosal injury and facilitates wound healing. However, its overexpression is known to induce hypertrophic gastropathy resembling Menetrier's disease in transgenic (TG) mice on an FVB
Yoneda Masashi, Sato Ken, Horiguchi Norio, Sohara Naondo, Kakizaki Satoru, Takagi Hitoshi, Kosone Takashi, Takeuchi Toshiyuki, Mori Masatomo   +8 more
doaj   +1 more source

Early onset, development and histological features of gastric signet-ring cell carcinoma

Frontiers in Oncology, 2023
ObjectiveTo explore the early onset, development and histological features of gastric signet-ring cell carcinoma (SRCC).MethodsThree hundred and sixty-two patients with differentiated adenocarcinoma with signet-ring cells were enrolled ...
Yangkun Wang, Yingying Li, Bin Wang, Dongmei Ran, Chaoya Zhu, Ping Li, Bo Jiang, Sunan Wang   +7 more
doaj   +1 more source

Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori [PDF]

, 2000
Background & Aims:Helicobacter pylori is believed to predispose to gastric cancer by inducing gastric atrophy and hypochlorhydria. First-degree relatives of patients with gastric cancer have an increased risk of developing gastric cancer.
El–Nujumi, Adil, El–Omar, Emad M., Fullarton, Grant, Gillen, Derek, McColl, Kenneth E.L., Murray, Lilian S., Oien, Karin, Williams, Craig, Wirz, Angela   +8 more
core   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Acute scrotum due to heterotopic gastric mucosa in Tunica vaginalis

Journal of Pediatric Surgery Case Reports, 2018
In adult and pediatric literature, most cases of heterotopic gastric mucosa are reported in gastrointestinal tract. Presences of gastric mucosa in genitourinary tract is unusual. We review the literature and report a case of 10-year old boy who presented
Zafar Nazir, Muhammad Arif Mateen Khan, Javaria Qamar   +2 more
doaj