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Usefulness of artificial intelligence in gastric neoplasms. [PDF]

open access: yesWorld J Gastroenterol, 2021
Recently, studies in many medical fields have reported that image analysis based on artificial intelligence (AI) can be used to analyze structures or features that are difficult to identify with human eyes. To diagnose early gastric cancer, related efforts such as narrow-band imaging technology are on-going.
Kim JH, Nam SJ, Park SC.
europepmc   +3 more sources

The dynamic alteration of transcriptional regulation by crucial TFs during tumorigenesis of gastric cancer

open access: yesMolecular Medicine, 2022
Background The mechanisms of Gastric cancer (GC) initiation and progression are complicated, at least partly owing to the dynamic changes of gene regulation during carcinogenesis. Thus, investigations on the changes in regulatory networks can improve the
Beiqin Yu   +13 more
doaj   +1 more source

Prediction Model of Tumor Regression Grade for Advanced Gastric Cancer After Preoperative Chemotherapy

open access: yesFrontiers in Oncology, 2021
BackgroundPreoperative chemotherapy (PCT) has been considered an important treatment for advanced gastric cancer (AGC). The tumor regression grade (TRG) system is an effective tool for the assessment of patient responses to PCT.
Wei Xu   +17 more
doaj   +1 more source

LncRNA MALAT1 promotes gastric cancer progression via inhibiting autophagic flux and inducing fibroblast activation

open access: yesCell Death and Disease, 2021
Autophagy defection contributes to inflammation dysregulation, which plays an important role in gastric cancer (GC) progression. Various studies have demonstrated that long noncoding RNA could function as novel regulators of autophagy.
Zhenqiang Wang   +6 more
doaj   +1 more source

Oxaliplatin plus S-1 with intraperitoneal paclitaxel for the treatment of Chinese advanced gastric cancer with peritoneal metastases

open access: yesBMC Cancer, 2021
Background In this study, we tried to access the efficacy and safety of oxaliplatin plus S-1 with intraperitoneal paclitaxel (PTX) for the treatment of Chinese advanced gastric cancer with peritoneal metastases.
Min Shi   +18 more
doaj   +1 more source

Tumor suppressor lnc-CTSLP4 inhibits EMT and metastasis of gastric cancer by attenuating HNRNPAB-dependent Snail transcription

open access: yesMolecular Therapy: Nucleic Acids, 2021
Tumor metastasis is a crucial impediment to the treatment of gastric cancer (GC), and the epithelial-to-mesenchymal transition (EMT) program plays a critical role for the initiation of GC metastasis.
Tao Pan   +15 more
doaj   +1 more source

Cancer-associated fibroblasts impair the cytotoxic function of NK cells in gastric cancer by inducing ferroptosis via iron regulation

open access: yesRedox Biology, 2023
As the predominant immunosuppressive component within the tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) inhibit Natural Killer cell (NK cell) activity to promote tumor progression and immune escape; however, the mechanisms of cross ...
Lizhong Yao   +14 more
doaj   +1 more source

Study protocol of a multicenter phase III randomized controlled trial investigating the efficiency of the combination of neoadjuvant chemotherapy (NAC) and neoadjuvant laparoscopic intraperitoneal hyperthermic chemotherapy (NLHIPEC) followed by R0 gastrectomy with intraoperative HIPEC for advanced gastric cancer (AGC): dragon II trial

open access: yesBMC Cancer, 2020
Background Even though treatment modalities such as adjuvant systemic radio-chemotherapy and neoadjuvant chemotherapy (NAC) have individually have improved overall survival (OS) and progression-free survival (PFS) rates in advanced Gastric Cancer (AGC ...
Maneesh Kumarsing Beeharry   +10 more
doaj   +1 more source

Gastric neuroendocrine neoplasms: A review

open access: yesWorld Journal of Clinical Cases, 2021
Gastric neuroendocrine neoplasms (g-NENs) or neuroendocrine tumors are generally slow-growing tumors with increasing incidence. They arise from enterochromaffin like cells and are divided into four types according to clinical characteristic features. Type 1 and 2 are gastrin dependent, whereas type 3 and 4 are sporadic.
Köseoğlu, Hüseyin   +2 more
openaire   +2 more sources

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