Results 21 to 30 of about 257,416 (262)

New Developments in Gastric Neuroendocrine Neoplasms [PDF]

Current Oncology Reports, 2022
AbstractPurpose of ReviewGastric neuroendocrine neoplasms (g-NENs) are a rare type of stomach cancer. The three main subtypes have different pathogeneses, biological behaviours and clinical characteristics, so they require different management strategies.
Exarchou, Klaire, Stephens, Nathan A., Moore, Andrew R., Howes, Nathan R., Pritchard, D. Mark   +4 more
openaire   +2 more sources

Efficacy and Safety of Conversion Therapy by Intraperitoneal and Intravenous Paclitaxel Plus Oral S-1 in Gastric Cancer Patients With Peritoneal Metastasis: A Prospective Phase II Study

Frontiers in Oncology, 2022
BackgroundNeoadjuvant intraperitoneal and systemic chemotherapy (NIPS) has shown promising results in gastric cancer (GC) with peritoneal metastasis. However, clinical practice experience of NIPS is still lacking in China.
Zhong-Yin Yang, Fei Yuan, Sheng Lu, Wei Xu, Jun-Wei Wu, Wen-Qi Xi, Min Shi, Zhen-Qiang Wang, Zhen-Tian Ni, Chang-Yu He, Xue-Xin Yao, Ya-Nan Zheng, Zheng-Lun Zhu, Wen-Tao Liu, Jun Zhang, Huan Zhang, Chen Li, Chao Yan, Min Yan, Zheng-Gang Zhu   +19 more
doaj   +1 more source

CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway

Journal of Experimental & Clinical Cancer Research, 2019
Background Gastric cancer (GC) has a clear predilection for metastasis toward the omentum which is primarily composed of adipose tissue, indicating that fatty acids may contribute to this phenomenon. However their function remains poorly understood in GC.
Jiaomeng Pan, Zhiyuan Fan, Zhenqiang Wang, Qingqiang Dai, Zhen Xiang, Fei Yuan, Min Yan, Zhenggang Zhu, Bingya Liu, Chen Li   +9 more
doaj   +1 more source

Progress and prospect of surgical comprehensive treatment of gastric cancer [PDF]

Waike lilun yu shijian, 2023
Gastric cancer is one of the leading malignancies in China and in the world. Surgery is still the most important modality to cure gastric cancer. A series of clinical researches changed the traditional concept of surgery and avoided blindly expanding the
ZHU Zhenggang
doaj   +1 more source

Palmitate acid promotes gastric cancer metastasis via FABP5/SP1/UCA1 pathway

Cancer Cell International, 2019
Background Gastric cancer (GC) has a clear predilection for metastasis toward omentum which is primarily composed of adipose tissue, combine with our previous research that long non-coding RNA Urothelial cancer associated 1 (UCA1) could promote the ...
Jiaomeng Pan, Qingqiang Dai, Tianqi Zhang, Chen Li   +3 more
doaj   +1 more source

Hotspots in basic and translational research of gastric cancer [PDF]

Waike lilun yu shijian, 2023
The morbidity and mortality of gastric cancer are high, while the overall therapeutic effect is poor without satisfactory. Clinical obstacles, such as low early-diagnosis rate, tumor heterogeneity, lack of accurate classification and precise treatment ...
LI Jianfang, YU Junxian, YAN Chao, ZHU Zhenggang, LIU Bingya
doaj   +1 more source

CT-Based Radiomics Showing Generalization to Predict Tumor Regression Grade for Advanced Gastric Cancer Treated With Neoadjuvant Chemotherapy

Frontiers in Oncology, 2022
ObjectiveThe aim of this study was to develop and validate a radiomics model to predict treatment response in patients with advanced gastric cancer (AGC) sensitive to neoadjuvant therapies and verify its generalization among different regimens, including
Yong Chen, Wei Xu, Yan-Ling Li, Wentao Liu, Birendra Kumar Sah, Lan Wang, Zhihan Xu, Michael Wels, Yanan Zheng, Min Yan, Huan Zhang, Qianchen Ma, Zhenggang Zhu, Chen Li   +13 more
doaj   +1 more source

Adjuvant Chemotherapy in pT2N0M0 Gastric Cancer: Findings From a Retrospective Study

Frontiers in Pharmacology, 2022
Background: There is no global consensus on adjuvant chemotherapy (ACT) for pT2N0M0 gastric cancer. We conducted a retrospective study to reveal the role of ACT in such patients.Methods: Patients with pT2N0M0 gastric cancer who underwent radical ...
Yu Mei, Xijia Feng, Tienan Feng, Min Yan, Zhenggang Zhu, Tian Li, Zhenglun Zhu   +6 more
doaj   +1 more source

Genetic Profiles Affect the Biological Effects of Serine on Gastric Cancer Cells

Frontiers in Pharmacology, 2020
A high serine content in body fluid was identified in a portion of patients with gastric cancer, but its biological significance was not clear. Here, we investigated the biological effect of serine on gastric cancer cells.
Jun Li, Hongzhang Xue, Zhen Xiang, Shuzheng Song, Ranlin Yan, Jun Ji, Zhenggang Zhu, Chaochun Wei, Chaochun Wei, Yingyan Yu   +9 more
doaj   +1 more source

VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancerResearch in context

EBioMedicine, 2023
Summary: Background: Vacuolar protein sorting-associated protein 35 (VPS35) is a core component of the retromer complex which mediates intracellular protein transport. It is well known that dysfunctional VPS35 functions in the accumulation of pathogenic
Junxian Yu, Haoran Feng, Qingqing Sang, Fangyuan Li, Mengdi Chen, Beiqin Yu, Zhuoqing Xu, Tao Pan, Xiongyan Wu, Junyi Hou, Zhenggang Zhu, Chao Yan, Liping Su, Jianfang Li, Bingya Liu   +14 more
doaj   +1 more source