Results 51 to 60 of about 13,207 (211)

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Precancerous Lesions in Gastrointestinal Tract

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2017
Gastrointestinal cancer is one of the health problems which is frequently found in many people in the world until now. Studies in gastrointestinal cancer showed early detection can reduce morbidity and improve the survival of patients.
Marcellus Simadibrata, Randy Adiwinata
doaj   +1 more source

Association between cytokine gene polymorphisms and gastric precancerous lesions : systematic review and meta-analysis [PDF]

, 2010
Polymorphisms within interleukin-1 (IL1) and tumor necrosis factor α (TNFA) gene clusters are associated with an increased risk of gastric cancer. However, their role in gastric precancerous lesions remains poorly understood. Our objective was to perform
Machado, JC, Durães, C, Barros, H, La Vecchia, C, C. Durães, Lunet, N, B. Peleteiro, N. Lunet, J. C. Machado, Carrilho, C, H. Barros, C. La Vecchia, Peleteiro, B, C. Carrilho   +13 more
core   +1 more source

The chemokine receptor CXCR4 is associated with the staging of gastric cancer

Advanced Biomedical Research, 2014
Background: CXCR4 is a cognitive receptor for stromal-derived factor-1 (SDF-1) and has been previously shown to be associated with tumor growth and invasion of many cancers.
Mehrnoush Nikzaban, Mohammad Said Hakhamaneshi, Shohreh Fakhari, Farshad Sheikhesmaili, Daem Roshani, Behzad Ahsan, Fatemeh Kamali, Ali Jalili   +7 more
doaj   +1 more source

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad, Francesc Balaguer, Elizabeth E. Half, Kevin J. Monahan, Elena M. Stoffel, Sonia S. Kupfer   +5 more
wiley   +1 more source

Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival

International Journal of Cancer, EarlyView.
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li, Elaheh Zarean, Danmeng Lily Li, Yiyue Zhu, Shuai Li, Enes Makalic, Catriona McLean, Graham G. Giles, Roger L. Milne, Melissa C. Southey, Pierre‐Antoine Dugué   +10 more
wiley   +1 more source

Revealing the key modules and potential prognostic markers of gastric cancer transformation based on weighted gene co-expression networks

Frontiers in Genetics
BackgroundThis study aims to identify key modules and targets during the transition from gastric precancerous lesions to gastric cancer by performing weighted gene co-expression network analysis (WGCNA) on gene microarray datasets from the Gene ...
Heng Li, Wen Li, Zhen Yang, Haiyu Liu, Xiaoping Zhang, Yufeng Zhao, Hao Gu   +6 more
doaj   +1 more source

Helicobacter Pylori infection among Iranian patients with normal upper gastrointestinal endoscopy

Caspian Journal of Internal Medicine, 2022
Background: Helicobacter pylori infection can be a risk factor for non-cardia gastric cancer. In the present study, we aimed to assess the rate of Helicobacter pylori infection, its virulence factor and precancerous lesion among over 50 years old ...
Hassan Salmanroghani, Mohammad Hassan Rouzegari, Roham Salmanroghani   +2 more
doaj  

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin, Dong Keon Kim, Yoojeong Seo, Hyeon Hee Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Jongwon Oh, Sanghoo Lee, Tae Il Kim   +10 more
wiley   +1 more source

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

iMetaMed, EarlyView.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang, Zhen Ma, Yang Li, Shaoli Wang, Yanjiao Zhang, Lei Song, Xianyu Li, Zhen Liu   +7 more
wiley   +1 more source