Results 61 to 70 of about 19,776 (223)

Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]

, 2014
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa, Bryk, Jarek, Futyma, Konrad, Lorenc, Anna, Miotla, Pawel, Putowski, Lechoslaw, Semczuk, Andrzej   +6 more
core   +1 more source

Gastric Precancerous lesions among Nigerians with Chronic Gastritis

Nigerian Postgraduate Medical Journal, 2012
To investigate the frequency of precancerous lesions in H. pylori gastritis in NigeriansPreviously, the slides of all endoscopic gastroduodenal biopsies seen at the Pathology Department of Obafemi Awolowo University Teaching Hospital, Ile-Ife between 1994 and 2003 were reviewed and published.
K B Badmos, O S Ojo, B J Olasode, A O Arigbabu   +3 more
openaire   +3 more sources

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase [PDF]

, 2014
Helicobacter pylori infection causes gastric cancer, the third leading cause of cancer death worldwide. More than half of the world’s population is infected, making universal eradication impractical. Clinical trials suggest that antibiotic treatment only
Asim, M, Barry, D P, Bravo, L E, Casero, R A, Chaturvedi, R, Correa, P, de Sablet, T, Delgado, A G, Fox, James G, Hardbower, D M, Israel, D A, Morgan, D R, Murray-Stewart, T, Nagy, T A, Peek, R M, Piazuelo, M B, Romero-Gallo, J, Schneider, B G, Sierra, J C, Verriere, T G, Wilson, K T, Woster, P M   +21 more
core   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

The chemokine receptor CXCR4 is associated with the staging of gastric cancer

Advanced Biomedical Research, 2014
Background: CXCR4 is a cognitive receptor for stromal-derived factor-1 (SDF-1) and has been previously shown to be associated with tumor growth and invasion of many cancers.
Mehrnoush Nikzaban, Mohammad Said Hakhamaneshi, Shohreh Fakhari, Farshad Sheikhesmaili, Daem Roshani, Behzad Ahsan, Fatemeh Kamali, Ali Jalili   +7 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Risk factors in gastric cancer [PDF]

, 2010
STATE OF THE ART: Gastric cancer (GC) is still a major health problem worldwide due to its frequency, poor prognosis and limited treatment options. At present prevention is likely to be the most effective means of reducing the incidence and mortality ...
COMPARE, DEBORA, NARDONE, GERARDO ANTONIO PIO, ROCCO, ALBA   +2 more
core  

Recommendations of the Chilean association for digestive endoscopy for the management of gastric pre-malignant lesions [PDF]

, 2014
Indexación: Web of Science; Scielo.An expert panel analyzed the available evidence and reached a consensus to release 24 recommendations for primary and secondary prevention of gastric cancer (CG) in symptomatic patients, with indication for upper GI ...
Araya, Raúl, Bufadel, María Ester, Calvo, Alfonso, Contreras, Luis, Cortés, Pablo, Estay, René, Estela, Ricardo, Fluxá, Fernando, Gatica, María de los Ángeles, Gobelet, Jaquelina, González, Robinson, Heredia, Carolina, Muñoz, Pablo, Nazal, Roberto, Osorio, Ingrid, Parra-Blanco, Adolfo, Pisano, Raúl, Rollán, Antonio, Squella, Freddy   +18 more
core   +1 more source

Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features [PDF]

, 2002
Background The growth and metastasis of tumors depend on the development of an adequate blood supply via angiogenesis. Recent studies indicate that the inducible nitric oxide synthase (iNOS), vascular endothelial growth factor (VEGF) and the tumor ...
Chang Wei Feng, Li Dong Wang, Lian Hua Jiao, Bin Liu, Shu Zheng, Xin Ji Xie, S Ambs, S Ambs, S Ambs, V Chiarugi, P Correa, M Devavrata, K Forrester, DC Jekins, A Nomura, LD Wang, World Health Organization, WC You, LL Zhang, Y Maehara, T Sakatani, M Ikeguchi, H Saito, K Maeda, A Rajnakova   +24 more
core   +2 more sources