Results 81 to 90 of about 19,776 (223)

Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer

Med Research, EarlyView.
ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang, Chenchen Wang, Tianliang Liu, Ziliang Wang, Zhe Zhang   +4 more
wiley   +1 more source

Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials [PDF]

, 2014
OBJECTIVES: To determine whether searching for Helicobacter pylori and treating with eradication therapy leads to a reduction in incidence of gastric cancer among healthy asymptomatic infected individuals.
Ford, AC, Forman, D, Hunt, RH, Moayyedi, P, Yuan, Y   +4 more
core   +2 more sources

Gastric Section Correlation Network for Gastric Precancerous Lesion Diagnosis

IEEE Open Journal of Engineering in Medicine and Biology
Goal: Diagnosing the corpus-predominant gastritis index (CGI) which is an early precancerous lesion in the stomach has been shown its effectiveness in identifying high gastric cancer risk patients for preventive healthcare. However, invasive biopsies and time-consuming pathological analysis are required for the CGI diagnosis.
Jyun-Yao Jhang, Yu-Ching Tsai, Tzu-Chun Hsu, Chun-Rong Huang, Hsiu-Chi Cheng, Bor-Shyang Sheu   +5 more
openaire   +3 more sources

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

17Beta-estradiol modulates gastroduodenal preneoplastic alterations in rats exposed to the carcinogen N-methyl-N'-nitro-nitrosoguanidine [PDF]

, 1999
Gastric cancers are a significant cause of morbidity worldwide. Epidemiological studies and animal models show that males have higher incidences of gastric cancers compared with females, suggesting that sex hormones may modulate gastric cancer risk.
Campbell-Thompson, M, Cromwell, J, Lauwers, G Y, Reyher, K K, Shiverick, K T   +4 more
core   +2 more sources

Real-Time Gastric Juice Analysis in Cirrhotic Patients: Can We Avoid Unrewarding Gastric Biopsies?

GE: Portuguese Journal of Gastroenterology
Background: To search for H. pylori infection and gastric precancerous lesions in cirrhotic patients is worthwhile when considering the high incidence of peptic ulcers and gastric cancer in these patients.
Sergio Peralta, Vincenza Calvaruso, Francesca Di Giorgio, Marco Peralta, Vincenzo Di Martino, Ada Maria Florena, Angelo Zullo   +6 more
doaj   +1 more source

Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression [PDF]

, 2017
Gastrointestinal cancer is a group of tumors that affect multiple sites of the digestive system, including the stomach, liver, colon and pancreas. These cancers are very aggressive and rapidly metastasize, thus identifying effective targets is crucial ...
Bacigalupo, Maria Lorena, Carabias, Pablo, Troncoso, María Fernanda   +2 more
core   +1 more source

Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes

Pathologica, 2020
Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently diagnosed malignancy and the third leading cause of cancer related death. Gastric carcinogenesis is a multistep and multifactorial process and is the result of the complex interplay between genetic susceptibility and environmental factors.
Gullo, Irene, Grillo, Federica, Mastracci, Luca, Vanoli, Alessandro, Carneiro, Fatima, Saragoni, Luca, Limarzi, Francesco, Ferro, Jacopo, Parente, Paola, Fassan, Matteo   +9 more
openaire   +5 more sources

Development and Validation of an Individualized Nomogram to Identify Undifferentiated‐Predominant Mixed‐Type Early Gastric Cancer

Journal of Digestive Diseases, EarlyView.
This study identified open‐type atrophic gastritis, flat or depressed morphology, faded appearance, tumor location on the greater curvature or anterior wall, xanthoma, and previous Helicobacter pylori eradication as independent risk factors for undifferentiated‐type‐predominant mixed‐type early gastric cancer (UM‐EGC).
Lin Lin Shao, Yu Miao Zheng, Qian Zhang, Chuan Guo Guo, Peng Li   +4 more
wiley   +1 more source

Epigenetic dynamics in gastric cancer precancerous lesions: From molecular mechanisms to precision risk stratification

Clinical and Translational Discovery
Gastric cancer continues to be a major threat to global health, accounting for a significant number of cancer deaths annually, with precancerous lesions representing critical intervention windows to halt malignant progression. Current risk stratification
Kewei Ma, Guanqi Shi, Xiao Li, Wanwei Zheng, Zhongguang Luo   +4 more
doaj   +1 more source