Results 81 to 90 of about 13,207 (211)

Gastric Mucosal Molecular Alterations and Multimodal Field‐Based Risk Models for Gastric Cancer Development

Cancer Science, EarlyView.
DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley   +1 more source

Helicobacter pylori Eradication Reduces the Metachronous Recurrence of Gastric Neoplasms by Attenuating the Precancerous Process [PDF]

, 2015
PURPOSE: The importance of Helicobacter pylori eradication after endoscopic resection (ER) of gastric neoplasms remains controversial. In this study, we clarified the importance of H. pylori eradication for metachronous lesions after ER.
정현수, 김지현, 김현기, 김호근, 박효진, 박준철, 윤영훈, 이상길, 정다현, 박재준, 이용찬, 김용훈, 신성관   +12 more
core   +1 more source

Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression

Frontiers in Microbiology, 2018
Helicobacter pylori (H. pylori) infection is the major risk factor associated with the development of gastric cancer. The transition from normal mucosa to non-atrophic gastritis, triggered primarily by H.
Paula Díaz, Paula Díaz, Paula Díaz, Manuel Valenzuela Valderrama, Manuel Valenzuela Valderrama, Manuel Valenzuela Valderrama, Jimena Bravo, Jimena Bravo, Jimena Bravo, Andrew F. G. Quest, Andrew F. G. Quest, Andrew F. G. Quest   +11 more
doaj   +1 more source

Differences in the Gastric Microbiotas of Neighboring Populations With Divergent Risks of Gastric Cancer

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Although Helicobacter pylori plays a central role in gastric cancer (GC), other microorganisms involved in gastric dysbiosis may also impact carcinogenesis. We aimed to characterize gastric dysbiosis and its role in the transition from non‐atrophic gastritis (NAG) to gastric premalignant lesions (GPLs) in two populations from Nariño,
Juan Camilo Caguazango, Karla Vinasco, Isidora Simovic, Yomaira Yépez Caicedo, Marino Coral Bedoya, Nadeem O. Kaakoush, Natalia Castaño‐Rodríguez   +6 more
wiley   +1 more source

Gastric Cancer Mortality in a High Incidence Area: Long-term follow-up of Helicobacter pylori-related Precancerous Lesions in the General Population [PDF]

BACKGROUND: Due to a lack of clear criteria for recognizing subjects at risk of progression to gastric cancer (GC), this cohort study seeks to identify predictors of GC death in a high-risk population. METHODS: During 2000-2001, 1011 randomly selected
نیک منش, آرش, بابایی, مسعود, احمدی, عماد, شریفی, امیر هوشنگ, ستوده, مسعود, صمدی, فاطمه, پورفرضی, فرهاد, اعتمادی, آرش, هوشيار, افشين, بوریری, مجید, یزدانبد, عباس, علیمحمدیان , معصومه   +11 more
core  

Long-Term Effects of Helicobacter pylori Eradication on Metachronous Gastric Cancer Development

Gut and Liver, 2018
Background/AimsGastric mucosal atrophy and intestinal metaplasia due to Helicobacter pylori infection are the main precursor lesions of gastric cancer. The aim of this study was to evaluate the long-term effects of H.
Seung Jun Han, Sang Gyun Kim, Joo Hyun Lim, Ji Min Choi, Sooyeon Oh, Jae Yong Park, Jung Kim, Joo Sung Kim, Hyun Chae Jung   +8 more
doaj   +1 more source

Features of cytokine balance in patients with precancerous gastric lesions depending on the changes in the structure of the thyroid gland

Gastroenterologìa, 2020
Background. The study of the cytokine balance is important due to searching the general links of the pathogenesis of comorbidity in precancerous gastric lesions and thyroid diseases.
L.M. Mosiychuk, I.V. Kushnirenko, O.M. Tatarchuk, I.S. Konenko, O.P. Petishko   +4 more
doaj   +1 more source

SDC1 Knockdown Suppresses Malignant Phenotypes of Breast Cancer by Modulating the MAPK Signaling Pathway

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Breast cancer remains a leading cause of morbidity and mortality among women worldwide, necessitating in‐depth research into its molecular mechanisms to improve prognosis and treatment strategies. This study investigates the expression profile and functional role of heparan sulfate proteoglycan Syndecan‐1 (SDC1) in breast cancer progression ...
Weixun Lin, Xiuying Chen, Juan Zou, Yanxian Chen, Zeqi Ji, Zhiyang Li, Bo Xu   +6 more
wiley   +1 more source

Artificial intelligence and oral microbiome: Reshaping the diagnostic and therapeutic paradigm of OSCC

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Schematic overview showing how microbiota‐induced epithelial dysbiosis initiates OSCC pathogenesis; multi‐omics sequencing paired with machine learning modelling constructs predictive biomarkers; the resultant high‐precision prediction tools support early tumour screening, lymph node metastasis risk evaluation and individualised targeted treatment for ...
Rui Shi, Yuan Zhi, Ling Gao, Shao‐Ming Li, Ke‐Qian Zhi, Wen‐Hao Ren   +5 more
wiley   +1 more source

UPPER GASTROINTESTINAL CANCER IN ARDABIL,NORTH-WEST OF IRAN: A REVIEW [PDF]

Introduction: Cancer is a serious health problem worldwide, imposing a large economical and psychological burden as well as loss of life and productivity.1 Lots of effort and money have been put in the fields of clinical, epidemiological, pharmacological,
ملک زاده, رضا, ناصری مقدم, سیاوش, یزدانبد, عباس   +2 more
core