Results 101 to 110 of about 782,279 (222)

Patterns of Esophageal Cancer Stage at Diagnosis: A Systematic Review of Registry‐Based Data

open access: yesJournal of Evidence-Based Medicine, EarlyView.
ABSTRACT Aims Stage at diagnosis is a key factor influencing survival in patients with esophageal cancer. This study aims to assess the distribution of esophageal cancer stage at diagnosis using registry data from multiple countries/regions. Methods PubMed, Embase, CNKI, and WanFang Data were systematically searched, supplemented by grey literature ...
Lanwei Guo   +10 more
wiley   +1 more source

Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia

open access: yesOral Diseases, EarlyView.
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio   +8 more
wiley   +1 more source

Assessing the effectiveness of Renzhu Jianwei Granula in managing precancerous lesions of gastric cancer: A meta-analysis of randomized clinical trials

open access: yesHeliyon
Background: Renzhu Jianwei Granula (RJG) is a traditional Chinese medicine compound initially formulated to address precancerous lesions for gastric cancer.
Tu Chen   +5 more
doaj   +1 more source

Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival

open access: yesInternational Journal of Cancer, Volume 159, Issue 10, Page 2452-2462, 15 November 2026.
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li   +10 more
wiley   +1 more source

Tobacco chewing habits and risk of precancerous oral lesions among Paniya tribes of Wayanad, India - a cross sectional study

open access: yes, 2018
Background Oral cancer is a major public health problem among Paniya tribes, a marginalized tribal group in Kerala state, South India. Previous studies have documented a high prevalence of tobacco chewing habit among Paniya tribals in Wayanad ...
Shanavas Palliyal
core   +1 more source

Helicobacter Pylori and Gastric Precancerous Lesions: An update

open access: yesGazi Medical Journal, 2015
Gastric cancer (GC) develops through a multistep process known as the gastritis-atrophy-metaplasia-dysplasia-cancer sequence associated with alterations in the expression of host oncogenes and tumor suppressor genes after several decades. Helicobacter pylori (H.
Alizadeh, Nasser   +5 more
openaire   +2 more sources

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

open access: yesInternational Journal of Cancer, Volume 159, Issue 10, Page 2585-2594, 15 November 2026.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin   +10 more
wiley   +1 more source

Value of c-Met for predicting progression of precancerous gastric lesions in rural Chinese population

open access: yes, 2012
To investigate the value of c-Met in predicting progression of precancerous gastric lesions. A population-based study was conducted to detect the overexpression of c-Met by immunohistochemical analysis in 124 subjects with precancerous gastric lesions.
Tian, Meng-meng   +4 more
core   +1 more source

FAM117A and PIGU regulate the trilogy of gastric carcinogenesis

open access: yesComputational and Structural Biotechnology Journal
Gastric cancer (GC) develops through a multistep process; however, the molecular mechanisms driving the progression from normal gastric mucosa to precancerous lesions and ultimately to GC remain incompletely understood.
Nianzhi Chen   +11 more
doaj   +1 more source

Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav   +4 more
wiley   +1 more source

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