Results 101 to 110 of about 19,776 (223)

Research progress of hepatocyte nuclear factor 4α in gastric cancer and precancerous lesions

Zhongguo linchuang yanjiu
Hepatocyte nuclear factor 4α (HNF4α) is a member of the nuclear receptor superfamily, a kind of protein that binds to a specific gene promoter. It controls the expression of functional genes and is also involved in the regulation of many cellular ...
YANG Yuyan, ZHAO Weihan, WANG Siyu, DONG Siqi
doaj   +1 more source

Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression

Frontiers in Microbiology, 2018
Helicobacter pylori (H. pylori) infection is the major risk factor associated with the development of gastric cancer. The transition from normal mucosa to non-atrophic gastritis, triggered primarily by H.
Paula Díaz, Paula Díaz, Paula Díaz, Manuel Valenzuela Valderrama, Manuel Valenzuela Valderrama, Manuel Valenzuela Valderrama, Jimena Bravo, Jimena Bravo, Jimena Bravo, Andrew F. G. Quest, Andrew F. G. Quest, Andrew F. G. Quest   +11 more
doaj   +1 more source

High chromosomal instability in adenocarcinoma of the ileum arising from multifocal gastric heterotopia with gastritis cystica profunda [PDF]

, 2010
Adenocarcinoma of the small intestine arising from heterotopic gastric mucosa is extremely rare. In this report, we present the case of a 68-year-old woman who complained of abdominal pain, weight loss and subileus.
Inga-Marie Schaefer, Philipp Schüler, Christina Enders, Jens-Gerd Scharf, Silke Cameron, Giuliano Ramadori, László Füzesi   +6 more
core   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source

Gastric Cancer Mortality in a High Incidence Area: Long-term follow-up of Helicobacter pylori-related Precancerous Lesions in the General Population [PDF]

BACKGROUND: Due to a lack of clear criteria for recognizing subjects at risk of progression to gastric cancer (GC), this cohort study seeks to identify predictors of GC death in a high-risk population. METHODS: During 2000-2001, 1011 randomly selected
احمدی, عماد, اعتمادی, آرش, بابایی, مسعود, بوریری, مجید, ستوده, مسعود, شریفی, امیر هوشنگ, صمدی, فاطمه, علیمحمدیان , معصومه, نیک منش, آرش, هوشيار, افشين, پورفرضی, فرهاد, یزدانبد, عباس   +11 more
core  

Juvenile polyposis in a SMAD4‐mutated child: A call for early surveillance

JPGN Reports, Volume 7, Issue 2, Page 262-265, May 2026.
Abstract We report the case of a 10‐year‐old boy with hereditary hemorrhagic telangiectasia (HHT) and a family history of SMAD4‐related juvenile polyposis syndrome (JPS), presenting with hypoferritinaemia unresponsive to oral supplementation. Endoscopic evaluation revealed multiple gastrointestinal polyps, including duodenal, gastric, and colonic ...
Claudia Lorusso, Giuseppe Lassandro, Stefania Castellaneta, Valentina Palladino, Giovanni la Grasta, Vanessa Nadia Dargenio, Vittorio Labriola, Alberto Gaeta, Paola Giordano, Fernanda Cristofori, Ruggiero Francavilla   +10 more
wiley   +1 more source

Long-Term Effects of Helicobacter pylori Eradication on Metachronous Gastric Cancer Development

Gut and Liver, 2018
Background/AimsGastric mucosal atrophy and intestinal metaplasia due to Helicobacter pylori infection are the main precursor lesions of gastric cancer. The aim of this study was to evaluate the long-term effects of H.
Seung Jun Han, Sang Gyun Kim, Joo Hyun Lim, Ji Min Choi, Sooyeon Oh, Jae Yong Park, Jung Kim, Joo Sung Kim, Hyun Chae Jung   +8 more
doaj   +1 more source

Features of cytokine balance in patients with precancerous gastric lesions depending on the changes in the structure of the thyroid gland

Gastroenterologìa, 2020
Background. The study of the cytokine balance is important due to searching the general links of the pathogenesis of comorbidity in precancerous gastric lesions and thyroid diseases.
L.M. Mosiychuk, I.V. Kushnirenko, O.M. Tatarchuk, I.S. Konenko, O.P. Petishko   +4 more
doaj   +1 more source

UPPER GASTROINTESTINAL CANCER IN ARDABIL,NORTH-WEST OF IRAN: A REVIEW [PDF]

Introduction: Cancer is a serious health problem worldwide, imposing a large economical and psychological burden as well as loss of life and productivity.1 Lots of effort and money have been put in the fields of clinical, epidemiological, pharmacological,
ملک زاده, رضا, ناصری مقدم, سیاوش, یزدانبد, عباس   +2 more
core  

GERD and Upper Aerodigestive Tract Cancer Risk: A Systematic Review and Meta‐Analysis

The Laryngoscope, Volume 136, Issue 5, Page 2008-2017, May 2026.
ABSTRACT Objective Gastroesophageal reflux disease (GERD) is highly prevalent, yet its association with upper aerodigestive tract (UADT) cancers beyond esophageal adenocarcinoma remains incompletely defined. This systematic review and meta‐analysis aimed to quantify the risk of specific UADT cancers in individuals with GERD.
Janice Huang, Nicolas Jo, Garret Forman, Tonya Aaron, Sophia Peifer, Soumil Prasad, Luke van Leeuwen, Laura Wild, Nicholas DiStefano, Zhibin Chen, Elizabeth Franzmann   +10 more
wiley   +1 more source