Results 101 to 110 of about 13,207 (211)

Helicobacter Pylori and Gastric Precancerous Lesions: An Update

open access: yesGazi Medical Journal, 2015
Mide kanseri birkaç dekad boyunca konak onkogenleri ve tümör supresör genlerde meydana gelen değişikliklerle ilişkili olarak gastrit-metaplazidisplazi-kanser sıralaması olarak bilinen birçok-basamaklı-süreç içerisinde gelişir. Helikobakter Pilori (H.
Önal, İbrahim Koral   +4 more
openaire   +4 more sources

Application of artificial intelligence-assisted digestive endoscopy in the diagnosis of early gastric cancer and precancerous lesions

open access: yesXin yixue
ObjectiveTo investigate the application of artificial intelligence (AI)-assisted digestive endoscopy in the diagnosis of early gastric cancer and precancerous lesions.
Yulong WANG   +4 more
doaj   +1 more source

Interpretation of 2025 American College of Gastroenterology Clinical Guidelines: Diagnosis and Management of Gastric Precancerous Lesions [PDF]

open access: yesZhenduanxue lilun yu shijian
In 2022, there were approximately 970 000 new cases and 660 000 deaths from gastric cancer worldwide, with East Asia (such as China, Japan, and South Korea) being the main high-incidence regions.
ZOU Tianhui
doaj   +1 more source

Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Tumor progression is driven by heterogeneity occurring across multiple biological scales. At the molecular level, tumor cells exhibit alterations across distinct omics layers, including genomic mutations, epigenomic reprogramming, transcriptional changes, and proteomic remodeling, collectively shaping tumor cell phenotypes and functional states.
Hanwen Hu   +5 more
wiley   +1 more source

The STAT3‐CCND2 Axis Drives a Proliferative Metaplastic Precursor Population in Gastric Intestinal Metaplasia

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 14, July 2026.
ABSTRACT Gastric intestinal metaplasia (GIM) is a crucial precancerous lesion with ill‐defined drivers, and identifying regulators of its early proliferation and reprogramming is key to interception. We integrated epigenomic‐transcriptomic analysis of human GIM and normal tissues, validated targets via dual‐luciferase assay, and mapped cellular ...
Fazhan Li   +4 more
wiley   +1 more source

Global cancer statistics 2024: GLOBOCAN estimates of incidence and mortality worldwide for 34 cancers in 186 countries

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.
Abstract This article provides updated global cancer statistics for the year 2024 based on the GLOBOCAN estimates of the International Agency for Research on Cancer. The authors describe national cancer incidence and mortality by world region and the Human Development Index and predict the burden in 2050 based on demographic trends.
Hyuna Sung   +7 more
wiley   +1 more source

Analysis of p53 expression in precancerous and malignant gastric mucosa [PDF]

open access: yes, 1998
P53 overexpression, detected by immunohistochemical analysis, has been reported in about 50% of gastric cancers whereas scarce data are available on the p53 oncoprotein in precancerous gastric lesions.
FRATI, Luigi   +10 more
core  

Effects of selective COX-2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions [PDF]

open access: yes, 2011
Objective: Helicobacter pylori infection and overexpression of cyclo-oxygenase-2 (COX-2) are associated with gastric cancer and its precursors. To evaluate the effect of a selective COX-2 inhibitor alone and combined with H pylori eradication on the ...
Zhang, Lian   +41 more
core   +1 more source

Assessing the effectiveness of Renzhu Jianwei Granula in managing precancerous lesions of gastric cancer: A meta-analysis of randomized clinical trials

open access: yesHeliyon
Background: Renzhu Jianwei Granula (RJG) is a traditional Chinese medicine compound initially formulated to address precancerous lesions for gastric cancer.
Tu Chen   +5 more
doaj   +1 more source

Complex pathologic differential diagnosis of precancerous processes and gastric cancer [PDF]

open access: yes, 2012
For the first time, a special comprehensive study of the phenotypes of dysplasia of gastric mucosa by histological techniques and their respective genomes using molecular-biological method of ISSR-PCR was performed.
A.V. Kharchenko, V.D. Markovskiy
core   +1 more source

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