Results 121 to 130 of about 19,776 (223)

Familial Adenomatous Polyposis—Risk of Cancer, Cancer Prevention, and Long‐Term Consequences: Learnings from Five Decades with the Danish Polyposis Register

open access: yesAPMIS, Volume 134, Issue 5, May 2026.
ABSTRACT Familial adenomatous polyposis (FAP) is a hereditary condition marked by the growth of hundreds to thousands of adenomatous polyps in the colon and rectum, significantly elevating the risk of colorectal cancer (CRC) if left untreated. Caused by pathogenic variants in the APC gene, FAP is typically identified in adolescence, often leading to ...
John Gásdal Karstensen
wiley   +1 more source

A multicenter validation of an endoscopic classification with narrow band imaging for gastric precancerous and cancerous lesions [PDF]

open access: yes, 2012
BACKGROUND AND STUDY AIM: The reliability and external validity of narrow band imaging (NBI) in the stomach have not been described consistently. The aim of the current study was to describe and estimate the accuracy and reliability of a simplified ...
Afonso, L.   +13 more
core   +2 more sources

Exosomal Non‐Coding RNAs in Gastrointestinal Cancer Drug Resistance: A Systematic Review of Emerging Mechanisms and Clinical Implications

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Gastrointestinal (GI) tumours are one of the most prevalent cancers globally. Even with normal GI function, individuals may develop neoplasms, highlighting the need to better understand the underlying causes of tumorigenesis. The emergence of tumour drug resistance represents the main reason for the failure of drug treatment; thus, it is ...
Mohsen Sharif‐zak   +6 more
wiley   +1 more source

Application of artificial intelligence-assisted digestive endoscopy in the diagnosis of early gastric cancer and precancerous lesions

open access: yesXin yixue
ObjectiveTo investigate the application of artificial intelligence (AI)-assisted digestive endoscopy in the diagnosis of early gastric cancer and precancerous lesions.
Yulong WANG   +4 more
doaj   +1 more source

Interpretation of 2025 American College of Gastroenterology Clinical Guidelines: Diagnosis and Management of Gastric Precancerous Lesions [PDF]

open access: yesZhenduanxue lilun yu shijian
In 2022, there were approximately 970 000 new cases and 660 000 deaths from gastric cancer worldwide, with East Asia (such as China, Japan, and South Korea) being the main high-incidence regions.
ZOU Tianhui
doaj   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh   +3 more
wiley   +1 more source

Loss of heterozygosity in multistage carcinogenesis of esophageal carcinoma at high-incidence area in Henan Province, China [PDF]

open access: yes, 2005
Aim: Microsatellites are the repeated DNA sequences scattered widely within the genomes and closely linked with many important genes. This study was designed to characterize the changes of microsatellite DNA loss of heterozygosity (LOH) in esophageal ...
An, JY   +8 more
core   +1 more source

Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]

open access: yes, 2015
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan   +3 more
core   +2 more sources

Cancer stem cell subsets and their relationships [PDF]

open access: yes, 2011
Emerging evidence suggests that cancer stem cells account for the initiation and progression of cancer. While many types of cancer stem cells with specific markers have been isolated and identified, a variety of differences among them began to be ...
Hai-Guang Liu   +4 more
core   +2 more sources

Assessing the effectiveness of Renzhu Jianwei Granula in managing precancerous lesions of gastric cancer: A meta-analysis of randomized clinical trials

open access: yesHeliyon
Background: Renzhu Jianwei Granula (RJG) is a traditional Chinese medicine compound initially formulated to address precancerous lesions for gastric cancer.
Tu Chen   +5 more
doaj   +1 more source

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