Results 61 to 70 of about 1,473,631 (241)

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Pyogenic spondylodiscitis of the lumbar spine related to anastomotic fistula after surgery for esophageal cancer: a case report

Surgical Case Reports, 2020
Background Pyogenic spondylodiscitis is an extremely rare complication of esophagectomy for esophageal cancer. Case presentation A 70-year-old Japanese man, with a previous medical history of type 2 diabetes mellitus, coronary artery disease, and ...
Yuichi Akama, Takeshi Matsutani, Nobutoshi Hagiwara, Hiroki Umezawa, Tsutomu Nomura, Hidetsugu Hanawa, Keisuke Mishima, Nobuhiko Taniai, Hiroshi Yoshida   +8 more
doaj   +1 more source

McKeown esophagectomy with concomitant median arcuate ligament release in a case of esophageal cancer with celiac artery stenosis

Surgical Case Reports, 2022
Background The celiac artery stenosis due to compression by median arcuate ligament (MAL) has been reported in many cases of pancreaticoduodenectomy, but not in cases of esophagectomy.
Keita Hanada, Shigeru Tsunoda, Satoshi Ogiso, Tatsuto Nishigori, Shigeo Hisamori, Kazutaka Obama   +5 more
doaj   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Clinical Implications of Microsatellite Instability in Early Gastric Cancer [PDF]

, 2019
Purpose: We aimed to evaluate the clinical characteristics of microsatellite instability in early gastric cancer. Materials and methods: The microsatellite instability status of resected early gastric tumors was evaluated using two mononucleotide ...
손태일, 서원준, 최윤영, 김현기, 형우진, 김동규, 최서희, 정재호, 노성훈, 김형일, 신수진, 조민아   +11 more
core   +1 more source

Gastric remnant carcinoma : histochemical and immunohistochemical profile [PDF]

, 2004
Includes bibliographical references (leaves 52-65).Gastric remnant carcinoma (GRC) is a gastric cancer that develops in gastric remnant more than five years after resection for benign disease. GRC comprises 1 %-9% of all gastric cancers.
Elazzabi, Tawfik
core   +1 more source

Current status of proximal gastrectomy for gastric and esophagogastric junctional cancer: A review

Annals of Gastroenterological Surgery, 2020
Proximal gastrectomy (PG) is one of the function‐preserving surgical methods for the treatment of upper gastric cancer. Favorable postoperative results have been reported in comparison with total gastrectomy.
Souya Nunobe, Satoshi Ida
doaj   +1 more source

Esophageal Resection, Gastric Tube Reconstruction, and Omental Flap Coverage of Iatrogenic Aortoesophageal Fistula After Secondary Thoracic Stentgraft Infection: A Case Report.

Annals of Vascular Surgery, 2019
Secondary stent graft infection is a life-threatening complication after thoracic endovascular aortic repair (TEVAR). There is no consensus on optimal treatment strategy, but combined antibiotic and surgical treatment is advocated.
F. Slieker, J. Ruurda, C. Hazenberg
semanticscholar   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source