Results 131 to 140 of about 818,241 (383)

Posterior perforation of gastric ulcer: A rare surgical emergency

open access: yesNigerian Journal of Medicine, 2017
BACKGROUND: Gastric ulcer perforation is a rare surgical emergency.Posterior gastric ulcer is even rarer and usually has a delayed presentation with attendant greater morbidity and mortality.
M O Afolayan, T O Olajide, O S Balogun
doaj   +1 more source

Incidence of major adverse cardiovascular events in patients with rheumatoid arthritis treated with Janus kinase inhibitors compared to biologic disease‐modifying antirheumatic drugs: data from an international collaboration of registries (the "JAK‐pot" study)

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the incidence of major adverse cardiovascular events (MACE) in RA patients treated with JAKi, TNF‐inhibitors (TNFi) or biologic Disease‐Modifying Anti‐Rheumatic Drugs with other modes of action (bDMARD‐OMA) in a multi‐country, real‐world population.
Romain Aymon   +28 more
wiley   +1 more source

Management of Helicobacter pylori infection

open access: yesJGH Open, Volume 7, Issue 1, Page 3-15, January 2023., 2023
Antibiotic‐resistant H. pylori strains have been increasing in most regions. Recommended first‐line regimens for H. pylori eradication are classified according to clarithromycin resistance. For patients with multiple treatment failure, antimicrobial susceptibility testing (AST) should be performed. Abstract Helicobacter pylori infection exhibits a wide
Natsuda Aumpan   +2 more
wiley   +1 more source

Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian   +5 more
wiley   +1 more source

Study on the Mechanism of Fu Zi Li Zhong Decoction in Treating Gastric Ulcer and its Effect on Gastrointestinal Microecology

open access: yesDigital Chinese Medicine, 2019
Objective: To explore the pharmacodynamic mechanism of Fu Zi Li Zhong Decoction (FZLZD) in treating gastric ulcer and its effect on gastrointestinal microecology. Methods: Rat gastric ulcer model was established by continuous vinegar gavage.
Huang Jia-Wang   +7 more
doaj  

Comparison of Emotion Regulation in Gastric Ulcer Sufferers and Non-Sufferers [PDF]

open access: yesJournal of Modern Psychology
Subjective: Psychological problems are involved in many psychosomatic disorders. Gastric ulcer is also related to psychological problems as one of the psychosomatic disorders.
Masoume Sobhi
doaj   +1 more source

Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia   +4 more
wiley   +1 more source

Effects of glepaglutide, a long‐acting glucagon‐like peptide‐2 analog, on intestinal morphology and perfusion in patients with short bowel syndrome: Findings from a randomized phase 2 trial

open access: yesJournal of Parenteral and Enteral Nutrition, Volume 47, Issue 1, Page 140-150, January 2023., 2023
Abstract Background The proadaptive effects of glucagon‐like peptide‐2 (GLP‐2) include stimulation of intestinal mucosal growth as well as intestinal blood flow and angiogenesis. We have recently reported that daily subcutaneous injections of glepaglutide, a long‐acting GLP‐2 analog, improved intestinal absorptive function in patients with short bowel ...
Rahim M. Naimi   +9 more
wiley   +1 more source

Magnetic-Guided Flexible Origami Robot toward Long-Term Phototherapy of H. pylori in the Stomach [PDF]

open access: yesarXiv
Helicobacter pylori, a pervasive bacterial infection associated with gastrointestinal disorders such as gastritis, peptic ulcer disease, and gastric cancer, impacts approximately 50% of the global population. The efficacy of standard clinical eradication therapies is diminishing due to the rise of antibiotic-resistant strains, necessitating alternative
arxiv  

In Silico Analysis of Tandem Repeats in GIF of Gastric Parietal Cells [PDF]

open access: yesarXiv, 2013
Tandem repeats are ubiquitous in the genome of organisms and their mutated forms play a vital role in pathogenesis. In this study, tandem repeats in Gastric Intrinsic Factor (GIF) of gastric parietal cells have been investigated using an in silico approach.
arxiv  

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