Results 51 to 60 of about 278,609 (254)

Metabolic Profiling of Heliotropium crispum Aerial Parts Using HPLC and FTIR and In Vivo Evaluation of Its Anti-Ulcer Activity Using an Ethanol Induced Acute Gastric Ulcer Model

Metabolites, 2022
This study explored the antiulcer potential of methanol extract and fractions of Heliotropium crispum roots against the ethanol-induced gastric ulcer model in rats. Metabolic profiling of H.
Syeda Farheen Fatima, Saiqa Ishtiaq, Manar O. Lashkar, Fadia S. Youssef, Mohamed L. Ashour, Sameh S. Elhady   +5 more
doaj   +1 more source

Clinical Profile and Outcome of Surgical Treatment of Perforated Peptic Ulcers in Northwestern Tanzania: A Tertiary Hospital Experience. [PDF]

, 2011
\ud \ud Perforated peptic ulcer is a serious complication of peptic ulcers with potential risk of grave complications. There is paucity of published reports on perforated peptic ulcer disease in our local environment. This study was conducted to evaluate
Kabangila Rodrick, Koy Mheta, Gilyoma, J.M., Gilyoma, Japhet M, Rodrick Kabangila, Rodrick Kabangila, R., Phillipo L Chalya, Chalya Phillipo L, Joseph B Mabula, Mchembe Mabula D, Hyasinta M Jaka, Koy, Mheta, Chandika, A.B., Chandika, Alphonce B, Mchembe, M.D., Mabula Joseph B, Gilyoma Japhet M, Mabula D Mchembe, Alphonce B Chandika, Chandika Alphonce B, Chalya, Phillipo L, Chalya, P.L., McHembe, Mabula D, Kabangila, Rodrick, Mabula, J.B., Koy, M., Mheta Koy, Jaka, H.M., Jaka, Hyasinta M, Jaka Hyasinta M, Japhet M Gilyoma, Mabula, Joseph B   +31 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Gastric cancer risk after Helicobacter pylori eradication in gastritis and peptic ulcer: a retrospective cohort study in Japan

BMC Gastroenterology
Background Helicobacter pylori infection is an important risk factor for gastric cancer. In Japan, national health insurance has covered eradication therapy for H. pylori infection–associated gastritis from 2013.
Kentaro Sugano, Chihiro Suzuki, Mihoko Ota, Ryuichi Iwakiri   +3 more
doaj   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Peptic Ulcer Disease Following Use of Bupropion: A Case Report

Clinical Medicine Insights: Case Reports, 2023
Background: Bupropion is a dopamine reuptake inhibitor, which is prescribed as an effective drug for the treatment of depression and as a complementary drug for smoking cessation in more than 50 countries.
Zahra Momayez Sanat, Negar Mohammadi Ganjaroudi, Ali Pirsalehi   +2 more
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Factors Associated with Recurrent Ulcers in Patients with Gastric Surgery after More Than 15 Years: A Cross-Sectional Single-Center Study

Gastroenterology Research and Practice, 2018
Aim. We aimed to establish the independent predictive factors (from Helicobacter pylori infection, biliary reflux, histologic features of the gastric mucosa, drugs, comorbidities, and social habits) for gastric stump ulcer occurrence more than 15 years ...
Monica Pantea, Anca Negovan, Claudia Banescu, Simona Bataga, Radu Neagoe, Simona Mocan, Mihaela Iancu   +6 more
doaj   +1 more source

Study on the Mechanism of Fu Zi Li Zhong Decoction in Treating Gastric Ulcer and its Effect on Gastrointestinal Microecology

Digital Chinese Medicine, 2019
Objective: To explore the pharmacodynamic mechanism of Fu Zi Li Zhong Decoction (FZLZD) in treating gastric ulcer and its effect on gastrointestinal microecology. Methods: Rat gastric ulcer model was established by continuous vinegar gavage.
Huang Jia-Wang, Yuan Ping, Xie Xi, Liao Can, Chen Ping-An, Wang Jian, Zhu Meng-Chen, Li Ling   +7 more
doaj   +1 more source