Results 61 to 70 of about 495,615 (294)

A TREATMENT OF GASTRIC ULCER [PDF]

Journal of the American Medical Association, 1912
In the treatment of gastric ulcer I have long taken advantage of the reversal of the fact that the ulcer is caused by the corrosive action of the gastric juice on the gastric mucosa. All will agree that the gastric juice is made up of the secretion of the peptic glands and hydrochloric acid and we know that neither of these will act as a digestant ...
openaire   +1 more source

Hydroxyproline, a Serum Biomarker Candidate for Gastric Ulcer in Rats: A Comparison Study of Metabolic Analysis of Gastric Ulcer Models Induced by Ethanol, Stress, and Aspirin

, 2014
Gastrointestinal symptoms are a common manifestation of adverse drug effects. Non-steroid anti-inflammatory drugs (NSAIDs) are widely prescribed drugs that induce the serious side effect of gastric mucosal ulceration.
Maki Ohishi, Keiko Endo, Hitoshi Naraoka, Yoichi Miyamae, Kenichi Suzumura, Kenichiro Takeuchi, Masashi Honma, Jiro Seki, Tomoyoshi Soga, Takeji Ohata   +9 more
core   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Perforated gastric ulcer [PDF]

Postgraduate Medical Journal, 1985
Summary Thirty-four patients presenting with gastric perforation over a ten year period were studied, retrospectively. Five patients (14%) died either as a result of delay in treatment or wrong diagnosis. In addition, 2 patients (6%) died from postoperative complications.
J, Wilson-Macdonald, N J, Mortensen, R C, Williamson   +2 more
openaire   +2 more sources

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Bibliometric and visualisation analyses of gastric ulcer knowledge areas and emerging trends, 2004–2024

Frontiers in Medicine
BackgroundGastric ulcers are a form of peptic ulcers that present as ruptures of the mucosal lining of the stomach or the proximal intestinal lining extending beyond the muscularis mucosae, and Helicobacter pylori infection is one of the main causative ...
Zijian Liu, Yi Liu, Yang Li, Yuyan Sun, Xiaoxiang Song, Lu Chen, Dan Zhou   +6 more
doaj   +1 more source

Protective effects of Cyclea barbata Miers leaves against aspirin-induced gastric ulcer in mice [PDF]

Universa Medicina, 2011
One side effect of non-steroidal anti-inflammatory drugs is gastric mucosal irritation, possibly causing gastric ulcers. The aim of this study was to evaluate the protective effect of cincau leaves (Cyclea barbata Miers) on aspirin-induced gastric ulcer ...
Iskandar Muda Siregar, Isnatin Miladiyah
doaj  

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

A comparison study of gastric cancer risk in patients with duodenal and gastric ulcer: Roles of gastric mucosal histology and p53 codon 72 polymorphism

, 2004
Gastric ulcer is positively, and duodenal ulcer negatively, associated with the risk of gastric cancer. The relationship between a common p53 polymorphism at codon 72 and gastric cancer risk in patients with gastric and duodenal ulcer was examined in 397
Holly, J., J Holly (16116380), Zhang, Z.W., Moganaden, Zhang, ZW, Storey, A., Farthing, MJG, Newcomb, P., Hollowood, A, Feakins, R., Alderson, D., Hollowood, A., A Hollowood (16116368), Newcomb, P, Gupta, J., Alderson, Derek, J Gupta (16116377), Moorghen, M, D Alderson (7634453), Feakins, R, P Newcomb (16116371), Z W Zhang (16115819), Storey, A, M J Farthing (16115624), Farthing, M.J.G., R Feakins (16115699), Holly, J, A Storey (9864653), Gupta, J, Moganaden (16116833)   +29 more
core   +5 more sources