Results 171 to 180 of about 40,702 (217)
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Current Medical Research and Opinion, 1974
SummaryDespite isolation in pure form, full chemical characterisation, synthetic production and sophisticated assay technique, the foregut hormone gastrin is probably still as great an enigma today as regards its role in disease as it was when Edkins first postulated its existence nearly 70 years ago.The authors review the recent work on the hormone ...
P J, Rooney, D, Grennan, J, Millar
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SummaryDespite isolation in pure form, full chemical characterisation, synthetic production and sophisticated assay technique, the foregut hormone gastrin is probably still as great an enigma today as regards its role in disease as it was when Edkins first postulated its existence nearly 70 years ago.The authors review the recent work on the hormone ...
P J, Rooney, D, Grennan, J, Millar
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Radioimmunoassay of Gastrin: Specificity of Gastrin Antisera
Scandinavian Journal of Gastroenterology, 1969Antisera for use in a gastrin radioimmunoassay have been prepared in two ways and their specificity compared. Antibodies to porcine antral gastrin were found to be specific for the N-terminal portion of the molecule; there was no cross-reaction with pentagastrin or pancreozymin.
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THE HETEROGENEITY OF GASTRIN, WITH REFERENCE TO CONVERSION OF GASTRIN‐17
Clinical Endocrinology, 1976SUMMARYHigh‐resolution gel chromatography monitored by a sensitive radioimmunoassay for gastrin has disclosed that gastrin circulates in twenty different components. Since the assay is specific for the biological active sequence of gastrin (‐Trp‐Met‐Asp‐PheNH2), we conclude that all the twenty circulating molecular forms of gastrin encountered in this ...
J F, Rehfeld +4 more
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Scandinavian Journal of Clinical and Laboratory Investigation, 2001
The days of the autumn 1970 when a gastrin assay was developed have been revisited, and the research conditions then and now compared. No valid conclusions seem possible from such a study, but a lot of facts suggest that the good old days were better.
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The days of the autumn 1970 when a gastrin assay was developed have been revisited, and the research conditions then and now compared. No valid conclusions seem possible from such a study, but a lot of facts suggest that the good old days were better.
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Antral Gastrin Cells and Serum Gastrin in Achlorhydria
Scandinavian Journal of Gastroenterology, 1977Forty-five patients with achlorhydria due to severe atrophic corpus gastritis or gastric atrophy were studied by determination of serum gastrin, histological examination of multiple biopsy from the antrum, and quantitation of gastrin cells revealed by an indirect immunofluorescence technique.
R, Stockbrügger +3 more
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1992
Publisher Summary This chapter describes the biology of the gastrin system and the involvement of gastrin in the development of various forms of cancer. The chapter presents new analytical methods for the measurement of gastrin in clinical oncology. Gastrin is a well-studied hormone that is discovered as a gastric acid-stimulating factor in extracts ...
J F, Rehfeld, L, Hilsted
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Publisher Summary This chapter describes the biology of the gastrin system and the involvement of gastrin in the development of various forms of cancer. The chapter presents new analytical methods for the measurement of gastrin in clinical oncology. Gastrin is a well-studied hormone that is discovered as a gastric acid-stimulating factor in extracts ...
J F, Rehfeld, L, Hilsted
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[Gastrin and gastrin receptor].
Nihon rinsho. Japanese journal of clinical medicine, 1996Gastrin is a well known endogenous stimulator of gastric acid. In addition, recent studies have revealed that gastrin has a growth promoting effect on gastric ECL cells. Indeed, development of ECL carcinoid tumor occurs almost exclusively in patients with hypergastrinemia such as autoimmune gastritis and Zollinger-Ellison syndrome with MEN type I.
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The antral Hormone Gastrin: Structure of Gastrin
Nature, 1964H, GREGORY +4 more
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