Results 51 to 60 of about 5,629 (238)

Cholecystokinin: Clinical aspects of the new biology

open access: yesJournal of Internal Medicine, Volume 298, Issue 3, Page 251-267, September 2025.
Abstract Cholecystokinin (CCK) is a classic gut hormone that has been known for almost a century to regulate gallbladder emptying, pancreatic enzyme secretion, and gastrointestinal motor activity. In 1968, the CCK structure was identified by Viktor Mutt and Erik Jorpes from porcine gut extracts as a peptide of 33 amino acid residues.
Jens F. Rehfeld
wiley   +1 more source

Features of multiple endocrine neoplasia type 1 the patient 48 years (MEN-1 in a patient of 48)

open access: yesЭндокринная хирургия, 2015
Given the unique observation of atypical MEN­1 (mixed version) of a man 48 years old, due to the presence 9 of multiple tumors and hyperplasia in 8 different organs (parathyroid glands, pancreatic and thyroid glands, duodenum, lung, stomach, skin and ...
Sergey Vladimirovich Sergуikо   +1 more
doaj   +1 more source

Type 2 and type 3 gastric neuroendocrine tumors have high risk of lymph node metastasis: Systematic review and meta‐analysis

open access: yesDigestive Endoscopy, Volume 37, Issue 8, Page 834-843, August 2025.
Objectives Lymph node metastasis (LNM) is crucial in determining treatment strategies for gastric neuroendocrine tumors (gNETs). While type 3 is considered more aggressive than types 1 and 2 within the clinical subtype of gNETs, the supporting data were insufficient, due to their rarity. We aimed to study the prevalence and risk factors associated with
Yohei Ogata   +9 more
wiley   +1 more source

Zollinger-Ellison syndrome: a case report

open access: yesZdravniški Vestnik, 2006
Background: Zollinger-Ellison syndrome is the consequence of excessive and autonomous secretion of gastrin from gastrinoma cells. The disease is exceptionally rare and characterized by severe and treatment-resistant peptic disease that can become life ...
Mitja Krajnc, Miro Čokolič
doaj  

Interferon-alpha-2a is a potent inhibitor of hormone secretion by cultured human pituitary adenomas [PDF]

open access: yes, 1999
Interferon-alpha (IFN alpha) may exert direct inhibitory effects on cell proliferation and on the production of different peptide hormones. We investigated the effect of IFN alpha on hormone production by 15 GH-secreting ...
Herder, W.W. (Wouter) de   +6 more
core  

Prognostic value of clinical parameters and exosomal lncRNA NEAT1_1 in MEN1‐related non‐functioning pancreatic neuroendocrine tumors

open access: yesJournal of Neuroendocrinology, Volume 37, Issue 8, August 2025.
Abstract Non‐functioning pancreatic neuroendocrine tumors (NF‐pNETs) significantly contribute to the premature death of multiple endocrine neoplasia type 1 (MEN1) patients. Reliable prognostic markers are not yet available. MicroRNAs (miRNA) and long‐non‐coding (lnc) RNAs, transported by extracellular vesicles, are emerging as new prognostic tools ...
Jerena Manoharan   +12 more
wiley   +1 more source

Gastrinoma tem ocorrência incomum na faixa etária pediátrica. Relato de um caso

open access: yesActa Gastroenterológica Latinoamericana, 2012
Los autores presentan los hallazgos clínicos, de laboratorio y radiológicos sugerentes de gastrinoma en un paciente de 1 año y 9 meses. Las pruebas de laboratorio obtenidas después de un ayuno revelaron una gastri - na sérica elevada, apoyando el ...
Guilherme Endrigo Fernandes   +3 more
doaj  

Pancreatic neuroendocrine tumors: classification, diagnosis and treatment – A review of the most frequent neuroendocrine tumors

open access: yesQuality in Sport
Neuroendocrine tumors (NETs) are a heterogeneous group of tumors originating from cells of the dispersed endocrine system. They vary in their degree of differentiation and malignancy.
Dominika Karolina Adamiec   +9 more
doaj   +1 more source

Risk and Protective Factors for the Occurrence of Sporadic Pancreatic Endocrine Neoplasms [PDF]

open access: yes, 2017
Pancreatic neuroendocrine neoplasms (PNENs) represent 10% of all pancreatic tumors by prevalence. Their incidence has reportedly increased over recent decades in parallel with that of pancreatic adenocarcinoma.
Capurso, Gabriele   +11 more
core   +1 more source

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