A Prospective Study on the Detection of Gastric Neoplasms Using Pepsinogen and Gastrin-17 Levels [PDF]
Gut and LiverBackground/Aims : GastroPanel tests include gastrin-17 (G-17) levels in addition to pepsinogen (PG) and Helicobacter pylori serology tests. The aim of this study was to identify significant test findings in patients with gastric neoplasms by comparing ...
Sun-Young Lee +5 more
doaj +2 more sources
Kidney Gastrin/CCKBR Attenuates Type 2 Diabetes Mellitus by Inhibiting SGLT2-Mediated Glucose Reabsorption through Erk/NF-κB Signaling Pathway [PDF]
Diabetes & Metabolism JournalBackground Both sodium-glucose cotransporters (SGLTs) and Na+/H+ exchangers (NHEs) rely on a favorable Na-electrochemical gradient. Gastrin, through the cholecystokinin B receptor (CCKBR), can induce natriuresis and diuresis by inhibiting renal NHEs ...
Xue Zhang +8 more
doaj +2 more sources
DIAGNOSTIC ACCURACY OF GASTROPANEL® FOR ATROPHIC GASTRITIS IN BRAZILIAN SUBJECTS AND THE EFFECT OF PROTON PUMP INHIBITORS [PDF]
Arquivos de Gastroenterologia, 2020 BACKGROUND: It has been proposed that the combination of gastrin-17 (G-17), pepsinogens I and II (PGI and PGII), and anti-Helicobacter pylori (H. pylori) antibodies (GastroPanel®, BIOHIT HealthCare, Helsinki, Finland) could serve as biomarkers of ...
Rejane MATTAR +5 more
doaj +1 more source
Progastrin represses the alternative activation of human macrophages and modulates their influence on colon cancer epithelial cells. [PDF]
PLoS ONE, 2014 Macrophage infiltration is a negative prognostic factor for most cancers but gastrointestinal tumors seem to be an exception. The effect of macrophages on cancer progression depends on their phenotype, which may vary between M1 (pro-inflammatory ...
Carlos Hernández +9 more
doaj +1 more source
Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China [PDF]
Journal of Preventive Medicine and Public Health, 2014 Objectives: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics.
Xiang-Quan Xie +6 more
doaj +1 more source
Biology, 2023 Multiple studies have reported new or exacerbated persistent or resistant hypertension in patients previously infected with COVID-19. We used literature-based discovery to identify and prioritize multi-scalar explanatory biology that relates resistant ...
David Kartchner +7 more
doaj +1 more source
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Berberis vulgaris (B. vulgaris) L. (Berberidaceae), deeply rooted in Iranian traditional medicine, exhibits significant antidiabetic potential attributed to its berberine content.
Hossein Salmanizadeh +2 more
doaj +1 more source
High Affinity Binding of Indium and Ruthenium Ions by Gastrins.
PLoS ONE, 2015 The peptide hormone gastrin binds two ferric ions with high affinity, and iron binding is essential for the biological activity of non-amidated forms of the hormone.
Graham S Baldwin +2 more
doaj +1 more source
Antral Gastrin Cell Hyperfunction Associated with Chronic Pancreatitis
Canadian Journal of Gastroenterology, 1988 This report describes a patient with antral gastrin cell hyperfunction who also had pancreatic pseudocyts and partial common bile duct obstruction secondary to chronic pancreatitis. A 60-year-old female had a th ree-month h istory of worsening epigastric
Atilla Ertan +3 more
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