Results 41 to 50 of about 2,001 (186)

Acute effects of N-terminal progastrin fragments on gastric acid secretion in man [PDF]

, 2017
We previously identified an N‐terminal fragment of progastrin in human antrum and plasma, where it circulates in high concentrations. In this study, we examined the effects of N‐terminal progastrin fragments on gastric acid secretion by infusion in ...
Goetze, Jens P, Hansen, Carsten P, Rehfeld, Jens F   +2 more
core   +1 more source

Rationalizing Proton Pump Inhibitor Use: Southeast Asia Consensus Recommendations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Proton pump inhibitors (PPIs) are integral to managing many gastrointestinal conditions. However, the prevalent inappropriate PPI prescription across Southeast Asia (SEA) is concerning. Given the absence of locally tailored recommendations to inform clinical practice, this consensus document aims to provide recommendations ...
Somchai Leelakusolvong, Tju Siang Chua, Duc Trong Quach, Andrew Ming‐Liang Ong, Ari Fahrial Syam, Augusto Jose G. Galang, Wee Kooi Cheah, Hang Viet Dao, Jose D. Sollano, Kalwinder Singh Khaira, Phuripong Kijdamrongthum, Rahela Ambaras Khan, Sakkarin Chirapongsathorn, Yeong Yeh Lee   +13 more
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Glycine-extended gastrin promotes the growth of lung cancer [PDF]

, 2004
The less processed forms of gastrin have recently been shown to act as trophic factors for both normal and malignant colonic cells. Although incompletely processed forms of gastrin such as glycine-extended gastrin and progastrin are also expressed in ...
Cui, Guanglin, Dockray, Graham J., Field, John K., Fielding, Pat, Houghton, JeanMarie, Koh, Theodore J., Liloglou, Triantafillos, Varro, Andrea, Wang, Timothy C.   +8 more
core   +2 more sources

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Transcriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution [PDF]

, 2016
Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.This work was supported by a PhD ...
Breese GR, Cabrero P, Chaet AB, Chang MM, Christie AE, Dockray GJ, Elphick MR, Elphick MR, Fujisawa J, Harada A, Johnsen AH, Kanatani H, Lee KY, Liddle RA, Nahon JL, Phlippen MK, Sawyer WH, Veenstra JA, Wilkie IC   +18 more
core   +1 more source

Efficacy of Abdominal Acupuncture in Poststroke Constipation: A Systematic Review and Meta‐Analysis With Trial Sequential Analysis

Brain and Behavior, Volume 16, Issue 5, May 2026.
ABSTRACT Background Poststroke constipation (PSC) is a prevalent and disabling condition that significantly affects patient quality of life. Although abdominal acupuncture (AA) has demonstrated potential therapeutic effects on PSC, its efficacy remains unclear.
Wulam Rukye, Hongzhi Yang, Yingjia Li, Xin Li, Nenggui Xu, Zhennan Wu   +5 more
wiley   +1 more source

Natriumbutyrat-induzierte Stimulation des humanen Gastrinpromotors und Identifizierung relevanter Response elements in den neuroendokrinen Pankreastumorzellen Bon I [PDF]

, 2006
Natriumbutyrat-induzierte Stimulation des humanen Gastrinpromotors und Identifizierung relevanter Response elements in den neuroendokrinen Pankreastumorzellen Bon ...
Freitag, Nicole, Maisch, Bernhard (Prof.Dr.)   +1 more
core   +1 more source

Identification of Prognostic Risk Factors in Older Patients With Extensive‐Stage Small Cell Lung Cancer

Cancer Medicine, Volume 15, Issue 5, May 2026.
The study corroborates the prognostic value of previously identified risk factors impacting progression‐free survival (PFS) and overall survival (OS) in older patients with extensive‐stage small cell lung cancer (ES‐SCLC). The figure was created with Microsoft PowerPoint.
Jiayin Liu, Xun Liu, Xiaolin Li, Ning Liu, Bo Wang, Li Feng, Zhisong Fan, Long Wang, Jing Han, Xue Zhang, Hui Jin, Dan Li, Yan Liu, Jing Zuo, Yudong Wang   +14 more
wiley   +1 more source