Results 41 to 50 of about 1,657 (182)

Connections between gastrins, iron and hypoxia in the development of colorectal cancer

, 2020
Gastrins, which are growth factors, and especially progastrin and glycine-extended gastrin (Ggly), are involved in the progression of colorectal cancer.
Laval, Marie
core  

Cytological Identification of a Rhabdoid Variant of Pancreatic Neuroendocrine Neoplasm

Cytopathology, EarlyView.
Intracytoplasmic inclusions observed in rhabdoid‐type neuroendocrine tumours are evident on Giemsa staining and show strong cytokeratin (AE1/AE3) positivity on immunocytochemistry. This report describes the cytological features of a rare rhabdoid variant of pancreatic neuroendocrine neoplasm and highlights the diagnostic challenges associated with this
Miyu Okuda, Keishi Mizuguchi, Tatsuya Mori, Urara Okawa, Hiroko Ikeda   +4 more
wiley   +1 more source

Structural insights into tyrosine sulfation of CCR5 by human tyrosylprotein sulfotransferase‐1

The FEBS Journal, EarlyView.
Structural analysis of human tyrosylprotein sulfotransferase‐1 (hTPST1) bound to a CCR5 N‐terminal peptide reveals how hTPST1 recognizes the Tyr3 sulfation site. Structure‐guided models of additional CCR5 sulfation states and full‐length assemblies provide a framework for understanding CCR5 tyrosine sulfation, a post‐translational modification relevant
Shinnosuke Tanaka, Hirai Asano, Kota Toyoda, Toshiaki Nishiyori, Hidetaka Kojo, Kazuto Kiyomatsu, Katsuhisa Kurogi, Yoichi Sakakibara, Etsuko Nishimoto, Takamasa Teramoto, Yoshimitsu Kakuta   +10 more
wiley   +1 more source

Method of meal delivery influences estimates of postprandial metabolism and alkaline tide in a benthic fish

Journal of Fish Biology, EarlyView.
Abstract Intragastric gavage is widely used in studies of digestive physiology to deliver standardised meals, yet it remains unclear whether it elicits postprandial metabolic and acid–base responses comparable to voluntary feeding. Here, we tested whether the method of meal delivery affects the magnitude and timing of the postprandial rise in metabolic
Junlin Chen, Barrett W. Wolfe, Harriet R. Goodrich   +2 more
wiley   +1 more source

Helicobacter pylori cag-Pathogenicity island-dependent early immunological response triggers later precancerous gastric changes in Mongolian gerbils [PDF]

, 2009
Infection with Helicobacter pylori, carrying a functional cag type IV secretion system (cag-T4SS) to inject the Cytotoxin associated antigen (CagA) into gastric cells, is associated with an increased risk for severe gastric diseases in humans.
Haas, Rainer, Rainer Haas, Wiedemann, Tobias, Loell, Eva, Tobias Wiedemann, Eva Loell, Susanna Mueller, Stolte, Manfred, Stoeckelhuber, Mechthild, Rieder, Gabriele, Manfred Stolte, Gabriele Rieder, Mueller, Susanna, Mechthild Stoeckelhuber   +13 more
core   +2 more sources

Cytologic, Clinicopathologic, and Histologic Findings in a Dog with a Gallbladder Neuroendocrine Carcinoma and Multiple Endocrinopathies

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 10‐year‐old spayed female Shih Tzu was evaluated for a gallbladder mass incidentally identified during a diagnostic workup for hyperadrenocorticism and persistent hypercalcemia. Diagnostic imaging revealed a vascularized intraluminal gallbladder mass, and cytologic examination showed cohesive clusters of epithelial cells with distinct ...
Sam Wicker, Alexis Johnson, Shelly Olin, Thomas Bevelock, Constance Fazio, Hiroyuki Mochizuki   +5 more
wiley   +1 more source

Naming progastrin-derived peptides

, 2004
The antral hormone gastrin continues to be in focus, because its hormonal and growth promoting effects are essential both for the function of the normal stomach and for the pathogenesis of major dyspeptic and neoplastic diseases.
Rehfeld, Jens F., Bundgaard, Jens R., Johnsen, Anders H., Goetze, Jens P., Friis-Hansen, Lennart, Hilsted, Linda   +5 more
core   +1 more source

The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract

The Journal of Physiology, EarlyView.
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley   +1 more source

Gastrin-deficient mice have disturbed hematopoiesis in response to iron deficiency

, 2011
Gastrins are peptide hormones important for gastric acid secretion and growth of the gastrointestinal mucosa. We have previously demonstrated that ferric ions bind to gastrins, that the gastrin-ferric ion complex interacts with the iron transport protein
Kovac, Suzana, Shulkes, Arthur, Graham S. Baldwin, Gregory J. Anderson, Warren S. Alexander, Alexander, Warren S., Suzana Kovac, Baldwin, Graham S., Arthur Shulkes, Anderson, Gregory J.   +9 more
core   +1 more source

Clinical Outcomes of Antrectomy for Patients With Multiple Type I Gastric Neuroendocrine Tumors: A Case Series

DEN Open, Volume 7, Issue 1, April 2027.
Type I gastric neuroendocrine tumors (T1‑GNETs) often present as multiple lesions, complicating treatment. This retrospective case series study evaluates antrectomy outcomes in eight patients with persistent multiple T1‑GNETs during 2005–2023. Following antrectomy, tumor regression was observed in two patients and complete disappearance in six, with ...
Yuki Morita, Ken Namikawa, Kaoru Nakano, Wataru Kurihara, Hiroyuki Yamamoto, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiyuki Yoshio, Souya Nunobe, Toshiaki Hirasawa   +9 more
wiley   +1 more source