Results 61 to 70 of about 1,657 (182)

Identification of Progastrin Derived Peptides in Colorectal-carcinoma Extracts

open access: yes, 1993
The possible production of gastrin by colorectal carcinomas has been studied. Extracts of 44 tumours and adjacent macroscopically normal tissue were examined in radioimmunoassay using the following antibodies: (i) L289 raised to a C-terminal fragment of ...
Dockray, GJ.   +4 more
core   +1 more source

Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions

open access: yes, 2015
Hypoxia, or a low concentration of O2, is encountered in humans undertaking activities such as mountain climbing and scuba diving and is important pathophysiologically as a limiting factor in tumor growth.
Shulkes, A   +3 more
core   +1 more source

Signaling the junctions in gut epithelium

open access: yes, 2005
This Perspective summarizes recent developments in our understanding of the signaling pathways involved in the regulation of epithelial cell adhesion in the gut. The role of phosphatidylinositol 3-kinase signaling in the modulation of adherens junctions,
Shulkes, A.   +2 more
core   +1 more source

Recent Patents and FDA-Approved Drugs Based on Antiviral Peptides and Other Peptide-Related Antivirals. [PDF]

open access: yesInt J Pept Res Ther, 2023
Mousavi Maleki MS   +3 more
europepmc   +1 more source

Chicken gastrin: a member of the gastrin/CCK family with novel structure-activity relationships

open access: yes, 1990
The biological activity of natural chicken gastrins isolated from the "antrum"-like region of the chicken gut have been studied on gastric secretion in chickens, turkeys, and rats, pancreatic secretion in turkeys and rats, and gallbladder contraction in
C. M. Lee, R. Dimaline
core   +1 more source

Can Scores on Alexithymia Distinguish Patients with Peptic Ulcer and Erosive Gastritis?

open access: yes, 1997
This study examined alexithymic characteristics of 57 patients with peptic ulcer and 198 with erosive gastritis. The prevalence rate of alexithymia, as measured on the 20-item Toronto Alexithymia Scale, was significantly higher for the peptic ulcer ...
Michiko Kikuchi   +3 more
core   +1 more source

Research Fellowship

open access: yes
My major goal for the past 20 years has been to understand how hormones such as gastrin stimulate the development of gastrointestinal cancer. One approach has been to define the intracellular signalling pathways by which gastrins enhance cell growth. Our

core  

Gastrin, Iron and Colorectal Cancer

open access: yes
Our objective is to understand the biological significance of the interaction between iron and the hormone gastrin. The project's significance to human health lies in the fact that gastrins stimulate growth of the lining of the stomach and colon ...

core  

GASTRIN CONTENT AND ACTIVITY IN SOME RUMINANTS AND SOME EQUINES

open access: yes, 1973
A Thesis presented for the degree of Doctor of Philosophy in the Department of Physiology, University of Ibadan, Ibadan, Nigeria.Attempts were made to extract gastrin from the cardiac, fundic pyloric, duedenal osecal and colonic mucosa of goats, sheep ...
OLOWO-OKORUN, M. O.
core  

Physiology and pathology of novel forms of progastrin

open access: yes
Gastrin is a stomach hormone which increases acid secretion and the growth of the stomach and bowel. This growth promoting effect may be involved in a number of cancers especially colon cancer.

core  

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