Results 201 to 210 of about 35,918 (226)

Annexin A2 in Tumors of the Gastrointestinal Tract, Liver, and Pancreas. [PDF]

Cancers (Basel)
Christofidis K, Pergaris A, Fioretzaki R, Charalampakis N, Kapetanakis EΙ, Kavantzas N, Schizas D, Sakellariou S.   +7 more
europepmc   +1 more source

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The gastrins: their production and biological activities.

Annual Review of Physiology, 2001
Gastric epithelial organization and function are controlled and maintained by a variety of endocrine and paracrine mediators. Peptides encoded by the gastrin gene are an important part of this system because targeted deletion of the gene, or of the ...
G. Dockray, A. Varró, R. Dimaline, T. Wang   +3 more
semanticscholar   +1 more source

Role of progastrins and gastrins and their receptors in GI and pancreatic cancers: targets for treatment.

Current pharmaceutical design, 2004
Accumulating evidence in literature suggests that amidated and non-amidated gastrins (gastrin precursors) may play an important role in the proliferation and carcinogenesis of gastrointestinal and pancreatic cancers, especially in the presence of DNA ...
W. Rengifo-Cam, Pomila Singh
semanticscholar   +1 more source

Corelease of amidated and glycine-extended antral gastrins after a meal.

American Journal of Physiology, 1988
Glycine-extended gastrin, the immediate precursor of bioactive (i.e., carboxyamidated) gastrin, was recently identified in antral tissue and in peripheral blood.
L. Hilsted, C. Hansen
semanticscholar   +1 more source

Incomplete processing of progastrin expressed by human colon cancer cells: role of noncarboxyamidated gastrins.

American Journal of Physiology, 1994
Gastrin is mitogenic for several colon cancers. To assess a possible autocrine role of gastrin in colon cancers, we examined human colon cancer cell lines for expression of gastrin mRNA and various forms of gastrin.
Pomila Singh, Zhidong Xu, B. Dai, Srinivasan Rajaraman, Norma H. Rubin, B. Dhruva   +5 more
semanticscholar   +1 more source

Pituitary gastrins occur in corticotrophs and melanotrophs.

Science, 1981
The gut hormone gastrin was identified in pituitary cells containing adrenocorticotropic hormone and alpha-melanocyte--stimulating hormone by region-specific immunocytochemistry and radioimmunoassay.
L. Larsson, J. Rehfeld
semanticscholar   +1 more source

Gastrins, iron and colorectal cancer.

Metallomics, 2009
This minireview explores the connections between circulating gastrins, iron status and colorectal cancer. The peptide hormone gastrin is a major regulator of acid secretion and a potent mitogen for normal and malignant gastrointestinal cells.
G. Baldwin
semanticscholar   +1 more source

Studies with two gastrin antisera of different specificity for gastrins I and II.

Digestion, 1974
Two gastrin antisera with different specificity for gastrins I and II have been compared by radioimmunoassay.
J. Hansky, C. Soveny, M. Korman
semanticscholar   +1 more source

Secretory effects of gastrins on isolated perfused porcine pancreas.

American Journal of Physiology, 1980
The effects of the four main forms of gastrin (component I, gastrin-34, gastrin-17, and gastrin-14) on insulin, glucagon, and exocrine secretion were measured on the isolated perfused porcine pancreas.
S. Jensen, J. Rehfeld, J. Holst, J. Fahrenkrug, O. Nielsen, O. B. Schaffalitzky de Muckadell   +5 more
semanticscholar   +1 more source