Results 41 to 50 of about 25,354 (168)

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Infection of Helicobacter pylori and Atrophic Gastritis Influence Lactobacillus in Gut Microbiota in a Japanese Population

Frontiers in Immunology, 2018
BackgroundSuppression of gastric acid by proton pump inhibitors is associated with the increase of Lactobacillus in human gut microbiota. Gastric acid secretion is also suppressed by Helicobacter pylori infection and following atrophic gastritis. However,
Chikara Iino, Chikara Iino, Tadashi Shimoyama, Daisuke Chinda, Tetsu Arai, Daisuke Chiba, Shigeyuki Nakaji, Shinsaku Fukuda   +7 more
doaj   +1 more source

P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders

Medicine Bulletin, EarlyView.
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley   +1 more source

FEATURES OF IMMUNE RESPONSE AMONG MAJOR LYMPHOCYTE SUBPOPULATIONS FROM PERIPHERAL BLOOD DURING EXACERBATION OF CHRONIC GASTRITIS

Медицинская иммунология, 2015
The aim of this study was to identify and evaluate the features of immune response for main subpopulations of peripheral blood lymphocytes during exacerbation of chronic gastritis, depending on the severity of gastric mucosal atrophy.
L. V. Matveeva
doaj   +1 more source

Gastric Microbiota Gender Differences in Subjects with Healthy Stomachs and Autoimmune Atrophic Gastritis

Microorganisms, 2023
Gender differences and microbiota are gaining increasing attention. This study aimed to assess gender differences in gastric bacterial microbiota between subjects with healthy stomachs and those with autoimmune atrophic gastritis.
Giulia Pivetta, Ludovica Dottori, Federico Fontana, Sophia Cingolani, Irene Ligato, Emanuele Dilaghi, Christian Milani, Marco Ventura, Marina Borro, Gianluca Esposito, Bruno Annibale, Edith Lahner   +11 more
doaj   +1 more source

Helicobacter Pylori Infection in Superficial Gastritis, Erosive Gastritis and Gastric Ulcer [PDF]

, 2012
Background: Helicobacter pylori (H. pylori) infection leads to inflammation of the gastric mucosa. It damages the gastric epithelium and related to the risk of developing gastric cancer. Over time, it may develop into the development of glandular atrophy
Abdullah, M. (Murdani), Albertus, J. (Jacobus), Rani, A. A. (Abdul), Simadibrata, M. (Marcellus), Syam, A. F. (Ari)   +4 more
core   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Modern strategy on managing patients with stomach pre-cancer

Лечащий Врач, 2021
The review summarize existing international recommendations for managing patients with atrophic gastritis, intestinal metaplasia and gastric dysplasia. It is shown that patients with chronic anthropic gastritis or intestinal metaplasia have an increased ...
L. B. Lazebnik, E. A. Lyalukova, G. V. Belova, I. V. Dolgalev, N. V. Korochanskaya, V. K. Kosenok, A. S. Lyalukova, E. V. Onuchina, M. M. Petrova, L. V. Prokhorova, A. S. Sarsenbaeva   +10 more
doaj  

Diagnosis and management of treatment-refractory hypothyroidism: an expert consensus report [PDF]

, 2017
There is a frequently encountered subset of hypothyroid patients who are refractory to standard thyroid hormone replacement treatment and require unexpectedly high doses of levothyroxine.
Benvenga, S, Centanni, Marco, Sachmechi, I.   +2 more
core   +1 more source

Tackling Post‐Endoscopy Gastric Cancer in a Low‐Risk Area: Prevalence, Features, and Prevention Opportunities Through Better Clinical Practice

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Post‐endoscopy gastric cancer (PEGC) is a gastric cancer (GC) diagnosed within 3 years after an esophago‐gastro‐duodenoscopy (EGD) negative for cancer. Post‐endoscopy gastric cancer has a prevalence of 9%–11% in the western population and is potentially reducible through adequate surveillance and high‐quality endoscopy.
Ricard Prat, Joan Llach, Sheyla Montori, Anabella Cuestas, Nayra Felípez, Alba Valero, Pedro Delgado‐Guillena, Javier Tejedor‐Tejada, Elena Arruebo, Silvia Patricia Ortega, Pilar Diez, Diana Zaffalon, Luis Hernández, Gadea Hontoria, Rosa María Saíz, Gonzalo Hijos‐Mallada, María José Domper, Sara Zarraquiños, Astrid Irene Díez‐Martín, Alberto Herreros, Diego de Frutos, Fátima Valentín, José Santiago, Virginia Piñol, Alicia Martín‐Lagos, Irina Luzko, Elisa Cantú‐Germano, Francesc Balaguer, Glòria Fernández‐Esparrach, Eduardo Albéniz, Leticia Moreira, on behalf ofEpiGASTRIC/EDGAR Consortium   +31 more
wiley   +1 more source