Efficient Biosynthesis of Gastrodin by UDP-Glycosyltransferase from <i>Rauvolfia serpentina</i>. [PDF]
J Microbiol BiotechnolGastrodin, the primary bioactive constituent of Gastrodia elata, possesses numerous remarkable pharmacological properties. In this investigation, UDP-glycosyltransferase from Rauvolfia serpentina (RsUGT) was expressed, subsequently purified and ...
Ge L, Xia Y, Xu W, Jia R, Zhang T.
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Comparative Transcriptomics Reveals the Molecular Basis for Inducer-Dependent Efficiency in Gastrodin Propionylation by Aspergillus oryzae Whole-Cell Biocatalyst [PDF]
BiomoleculesPropionylated derivatives of gastrodin are valuable due to their enhanced lipophilicity and bioavailability. This study investigated the molecular basis for the differential catalytic efficiency of Aspergillus oryzae whole cells in gastrodin ...
Desheng Wu +4 more
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Gastrodin: a potential natural product for the prevention and treatment of cerebral ischemia-reperfusion injury. [PDF]
Front PharmacolEthnopharmacological relevanceGastrodin is the main bioactive metabolite of Gastrodia elata Blume of traditional Chinese medicine, which has pharmacological effects such as anti-inflammatory, antioxidant, neuroprotective, vasoprotective, hypoglycemic ...
Qin W, Du J, Wang F, Xu J.
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Gastrodin Mitigates Ketamine-Induced Inhibition of F-Actin Remodeling and Cell Migration by Regulating the Rho Signaling Pathway [PDF]
BiomedicinesBackground/Objects: Rho signaling plays a role in calcium-regulated cytoskeletal reorganization and cell movement, processes linked to neuronal function and cancer metastasis. Gastrodia elata, a traditional herbal medicine, can regulate glutamate-induced
Ping-Cheng Shih +3 more
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Gastrodin plays a protective role in alleviating hepatic ischemia reperfusion injury by regulating heme oxygenase-1 expression. [PDF]
Braz J Med Biol ResHepatic ischemia reperfusion injury (HIRI) is a pathophysiological and complex systemic process involving multiple tissues and organs. Gastrodin (GSTD), a natural compound from Gastrodia elata, displays a variety of interesting pharmacological activities.
He SS +6 more
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Gastrodin: a comprehensive pharmacological review
Naunyn-Schmiedeberg's Archives of PharmacologyTianma is the dried tuber of Gastrodia elata Blume ( G. elata ), which is frequently utilized in clinical practice as a traditional Chinese medicine.
Yulin Wang +8 more
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Gastrodin enhances stress resilience through promoting Wnt/β-Catenin-dependent neurogenesis. [PDF]
J Adv ResZhang H +10 more
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Cardiovascular protective properties of gastrodin
Asian Pacific Journal of Tropical Biomedicine, 2022 Cardiovascular diseases cause significant morbidity and mortality worldwide, incurring a major public health burden. Gastrodia elata Blume is a traditional Chinese herbal medicine that has been widely used to treat central nervous system and ...
Shu-Ting Yang, Shu-Bai Liu
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Effectiveness of gastrodin for migraine: A meta-analysis
Frontiers in Neurology, 2022 BackgroundGastrodia elata Blume (GEB), a traditional Chinese medicine, has been widely used to treat dizziness, numbness of limbs, and infantile convulsion, among other issues. Gastrodin is the main component of GEB.
Xiu Zhou +5 more
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Gastrodin Derivatives from Gastrodia elata [PDF]
Natural Products and Bioprospecting, 2019 Nine new gastrodin derivatives, including seven p-hydroxybenzyl-modified gastrodin ethers (1–7), 6′-O-acetylgastrodin (8), and 4-[α-d-glucopyranosyl-(1 →6)-β-d-glucopyranosyloxy]benzyl alcohol (9), together with seven known derivatives, were isolated ...
Cheng-Bo Xu +5 more
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