Results 21 to 30 of about 4,691 (257)

Gastrodin Rescues Autistic-Like Phenotypes in Valproic Acid-Induced Animal Model [PDF]

Frontiers in Neurology, 2018
Autism spectrum disorder (ASD) is an immensely challenging developmental disorder characterized by impaired social interaction, restricted/repetitive behavior, and anxiety.
Xiaona Wang, Jing Tao, Yidan Qiao, Shuying Luo, Zhenqin Zhao, Yinbo Gao, Jisheng Guo, Jinghui Kong, Chongfen Chen, Lili Ge, Bo Zhang, Pengbo Guo, Lei Liu, Yinsen Song   +13 more
doaj   +3 more sources

Gastrodin Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitochondrial Fusion and Activating the AMPK-OPA1 Signaling Pathway. [PDF]

CNS Neurosci Ther
Cerebral ischemia–reperfusion (I/R) injury is a critical pathological process in stroke, characterized by disrupted energy metabolism, inflammatory responses, and mitochondrial dysfunction.
Liu Z, Han Z, Bao W, Guo Y, Yuan Y, Cheng J, Zhang J, Hu Y.   +7 more
europepmc   +3 more sources

Gastrodin modified polyurethane conduit promotes nerve repair via optimizing Schwann cells function

Bioactive Materials, 2022
Peripheral nerve regeneration and functional recovery remain a major clinical challenge. Nerve guidance conduit (NGC) that can regulate biological behavior of Schwann cells (SCs) and facilitate axonal regeneration through microenvironmental remodeling is
Hongcai Yang, Qing Li, Limei Li, Shaochun Chen, Yu Zhao, Yingrui Hu, Lu wang, Xiaoqian Lan, Lianmei Zhong, Di Lu   +9 more
doaj   +2 more sources

Electrical gastrodin-polyurethane spiral conduits with micro/nano-structure for accelerating peripheral nerve regeneration. [PDF]

Bioact Mater
Lan X, Feng G, Li Q, Qin S, Hu Y, Pan S, Jiao J, Lu D, Zhong L.   +8 more
europepmc   +2 more sources

Gastrodin and Vascular Dementia: Advances and Current Perspectives [PDF]

Evidence-Based Complementary and Alternative Medicine, 2022
Gastrodia elata, a traditional Chinese medicine, has been widely used since ancient times to treat diseases such as dizziness, epilepsy, stroke, and memory loss. Gastrodin, one of the active components of Gastrodia elata, has been used in the treatment of migraine, epilepsy, Parkinson’s disease, dementia, and depression in recent years.
Chujun Deng, Huize Chen, Zeyu Meng, Shengxi Meng   +3 more
  +5 more sources

Gastrodin Alleviates Angiotensin II-Induced Hypertension and Myocardial Apoptosis via Inhibition of the PRDX2/p53 Pathway In Vivo and In Vitro [PDF]

Pharmaceuticals
Gastrodin, a highly potent compound found in the traditional Chinese medicine Gastrodia elata Blume, exhibits significant antihypertensive properties. However, its role and the mechanism behind its protective effects on hypertensive cardiac conditions ...
Nanhui Xu, Qiurong Xie, Youqin Chen, Jiapeng Li, Xiuli Zhang, Huifang Zheng, Ying Cheng, Meizhu Wu, Aling Shen, Lihui Wei, Mengying Yao, Yanyan Yang, Thomas J. Sferra, Anjum Jafri, Yi Fang, Jun Peng   +15 more
doaj   +2 more sources

A Review on Central Nervous System Effects of Gastrodin [PDF]

Frontiers in Pharmacology, 2018
Rhizoma Gastrodiae (also known as Tian ma), the dried rhizome of Gastrodia elata Blume, is a famous Chinese herb that has been traditionally used for the treatment of headache, dizziness, spasm, epilepsy, stoke, amnesia and other disorders for centuries.
Yuan Liu, Yuan Liu, Jialiang Gao, Min Peng, Hongyan Meng, Hongbo Ma, Pingping Cai, Yuan Xu, Qiong Zhao, Guomin Si   +9 more
doaj   +3 more sources

Establishment of a new approach for quality evaluation of Pseudobulbus Cremastrae seu Pleiones (Shancigu) based on multicomponent analysis and anti-liver cancer pharmacological effects. [PDF]

Front Pharmacol
BackgroundPseudobulbus Cremastrae seu Pleiones (Shancigu), a traditional Chinese medicine (TCM), has been extensively used in clinical practice for the treatment of various tumors, particularly liver cancer.
Cao Y, Hao Z, Liu M, Xue J, Wang Y, Jiang T, Zhang G, Fan W, Wang C, Shi J.   +9 more
europepmc   +3 more sources

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain
Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory, antioxidant, antiapoptosis, and other aspects.
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
doaj   +2 more sources

Study on the uptake of Gastrodin in the liver

Heliyon
Background: Gastrodin is the active monomer of the Chinese herb Rhizoma Gastrodiae with the largest quantity of active components. Gastrodin is commonly used in the treatment of central nervous system disorders such as headaches and epilepsy due to its ...
Xing Wang, Wenzhu Yang, Jitong Lv, Xinya Liao   +3 more
doaj   +3 more sources