Results 51 to 60 of about 4,691 (257)
Gastrodin overcomes chemoresistance via inhibiting Skp2-mediated glycolysis
Cell Death Discovery, 2023 AbstractAerobic glycolysis, a typical phenotype in human tumors, is associated with tumor progression and chemotherapy resistance. The present study demonstrated that cisplatin-resistant oral squamous cell carcinoma (OSCC) cells exerted a stronger glycolysis ability, which was associated with hexokinase 2 (HK2) overexpression.
Li Xie +6 more
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Ameliorative Effect of Gastrodin on Aging and Inflammation of BV2 Cells by Regulating SIRT3
Shipin gongye ke-ji, 2022 Objective: In order to explore the protective effects and mechanism of gastrodin on BV2 cells treated with D-galactose. Methods: The BV2 cells were treated with D-galactose at different concentrations (10, 20, 30 and 40 μg/mL) for 24 h to establish a ...
Tong GUAN +4 more
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Microbial Cell Factories, 2020 Background The natural phenolic glycoside gastrodin is the major bioactive ingredient in the well-known Chinese herb Tianma and is widely used as a neuroprotective medicine in the clinic.
Hua Yin +3 more
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Adenosine A2A Receptor Blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism [PDF]
, 2016 Pharmacological studies implicate the blockade of adenosine receptorsas an effective strategy for reducing Parkinson’s disease (PD) symptoms. The objective of this study is to elucidate the possible protective effects of ZM241385 and 8-cyclopentyl-1, 3 ...
Ahmed A. Moustafa +4 more
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Highly efficient and enzymatic regioselective undecylenoylation of gastrodin in 2-methyltetrahydrofuran-containing systems. [PDF]
PLoS ONE, 2014 Highly efficient and regioselective acylation of pharmacologically interesting gastrodin with vinyl undecylenic acid has been firstly performed through an enzymatic approach. The highest catalytic activity and regioselectivity towards the acylation of 7'-
Rongling Yang +5 more
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Biological and Pharmaceutical Bulletin, 2010 Gastrodin, a major bioactive component of a famous Chinese herb B1., has diverse pharmaceutical functions. It is usually obtained by extraction from a plant or through chemical synthesis. However, traditional extraction from B1. is time and money consuming, while chemical synthesis is a complicated procedure and always leads to very serious ...
Hongli, Zhu +6 more
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Bioactive Materials, 2021 Vascular grafts must avoid negative inflammatory responses and thrombogenesis to prohibit fibrotic deposition immediately upon implantation and promote the regeneration of small diameter blood vessels (
Meng Zheng +10 more
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Evaluation of protective effect of cyclodextrin glucanotransferase-treated Gastrodia elata Blume extract on ultraviolet B-induced premature skin aging [PDF]
, 2019 Purpose: To investigate the protective effect of Gastrodia elata Blume (G. elata, GE) and cyclodextrin glucanotransferase (CGTase) enzyme-treated G. elata extract (EGE) against premature skin aging using ultraviolet B (UVB)-exposed normal human dermal ...
Bae, Jahyun +5 more
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Chinese Medicine, 2022 Background Dizziness and vertigo are common clinical symptoms. Gastrodin injection has shown clinical effects on dizziness or vertigo. However, little is known about the effectiveness and costs of combining Gastrodin injection with conventional treatment
Yunfeng Lai +9 more
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Foods, 2023 Gastrodin is one of the most important biologically active components of Gastrodia elata, which has many health benefits as a dietary and health food supplement.
Zhenjie Wang +7 more
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