Results 81 to 90 of about 4,691 (257)

Aspirin in combination with gastrodin protects cardiac function and mitigates gastric mucosal injury in response to myocardial ischemia/reperfusion

Frontiers in Pharmacology, 2022
Myocardial ischemia/reperfusion (I/R) injury after percutaneous coronary intervention (PCI) is common in acute myocardial infarction. Aspirin is commonly prescribed as anti-thrombotic therapy with coronary heart disease (CHD).
Zhiwu Dong, Lin Yang, Jianlin Jiao, Yongliang Jiang, Hao Li, Gaosheng Yin, Ping Yang, Ping Yang, Lin Sun   +8 more
doaj   +1 more source

Gastrodia elata Blume extract ameliorates exercise-induced fatigue [PDF]

, 2013
To investigate the effect of Gastrodia elata Blume (GEB) extract on exercise-induced fatigue recovery, 120 mice were divided at random into four experimental groups (3 GEB administered groups and the normal control group).
Bing, Yan, Zhaobao, Wang
core   +2 more sources

The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders. [PDF]

, 2021
Inflammation is the result of a complex network of cellular and molecular interactions and mechanisms that facilitate immune protection against intrinsic and extrinsic stimuli, particularly pathogens, to maintain homeostasis and promote tissue healing ...
Chong, WC, Dua, K, Hansbro, NG, Hansbro, PM, Hsu, AC, Johansen, MD, Patel, RP, Pathinayake, PS, Peterson, GM, Schroder, K, Shastri, MD, Shukla, SD, Wark, PA   +12 more
core   +2 more sources

GeARF5/GeIAA33‐GeSWEET14 module balances the secondary metabolic biosynthesis to increase the yield and quality in Gastrodia elata

Journal of Integrative Plant Biology, EarlyView.
Auxin signaling regulates the formation of vegetative propagation corms in Gastrodia elata by regulating sugar‐acid interconversion, which in turn regulates polysaccharide and starch biosynthesis as well as biosynthesis of the bioactive metabolite gastrodin.
Qun Liu, Zhiqing Wu, Yugang Gao, Yue Xu, Pu Zang, Xinyu Yang, Yan Zhao, Pan Liao, Benoît Boachon, Guoyin Kai   +9 more
wiley   +1 more source

Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Paning I decoction alleviated neuroinflammation in Parkinson's disease. ABSTRACT Background Parkinson's disease (PD) is a major neurodegenerative disorder. Some patients show limited response to standard therapies, driving the need for new complementary treatments.
Yan‐Jun Chen, Jing‐Wen Chen, Ming‐Rong Xie, Rui‐Zhen Wang, Yu‐Ling Wan, Jie Zeng, Bing‐Wu Zhong, Sheng‐Qiang Zhou, Fang Liu   +8 more
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Gastrodin regulates expression of angiotensin-SirT3 and proinflammatory mediators in reactive astrocytes via activated microglia [PDF]

, 2022
Hanjun Zuo, Xue‐Qi Ren, Kun Guo, Pengxiang Wang, Min Zhao, Juanjuan Li   +5 more
openalex   +1 more source

Gastrodin suppresses pyroptosis and exerts neuroprotective effect in traumatic brain injury model by inhibiting NLRP3 inflammasome signaling pathway

Journal of Integrative Neuroscience, 2022
Traumatic brain injury (TBI), also known as head injury or brain injury, refers to the head injury caused by mechanical impact. It is necessary to develop effective new therapies for TBI injury.
Fei Yang, Guangzhao Li, Bin Lin, Kaipeng Zhang   +3 more
doaj   +1 more source

Insights into the nutritional properties and molecular basis of biosynthesis of amino acids and vitamins of Gastrodia elata offered by metabolomic and transcriptomic analysis [PDF]

, 2023
Gastrodia elata Blume (GE), a traditional and precious Chinese medicinal material, has been approved as a functional food. However, understanding GE’s nutritional properties and its molecular basis remains limited.
Muhammad Qasim Shahid, Muhammad Qasim Shahid, Muhammad Qasim Shahid, Yunsheng Wang   +3 more
core   +1 more source

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

Food Safety and Health, Volume 4, Issue 1, Page 220-232, January 2026.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh, Md. Shimul Bhuia, Raihan Chowdhury, Md. Sakib Al Hasan, Most. Israt Jahan Oni, Imam Hossen Rakib, Mir Imran Alim, Jakia Sultana, Muhammad Torequl Islam   +8 more
wiley   +1 more source