Results 1 to 10 of about 8,469 (217)

Screening and characterization of monoclonal antibodies with neutralizing activity against porcine transmissible gastroenteritis virus. [PDF]

BMC Vet Res
Porcine Transmissible Gastroenteritis Virus (TGEV) is widespread and frequently involved in co-infections, leading to high mortality rates in piglets and significantly constraining the swine industry. Based on the genetic sequence of TGEV strain HB-1, we
Jia H, Song T, Zheng B, Wang X, Rui P, Yan S, Liu W, Ma Z.   +7 more
europepmc   +2 more sources

TRIM7 suppresses transmissible gastroenteritis virus replication by targeting the degradation of N protein and activating RIG-I-mediated type I IFN antiviral response. [PDF]

Vet Res
Transmissible gastroenteritis virus (TGEV) is a major enteric pathogen causing severe diarrhea in swine, with substantial implications for the biosecurity of intensive pig production worldwide. The E3 ubiquitin ligase TRIM7 has emerged as a key regulator
Qin W, Xie Y, Liang H, Wu Z, Yang S, Zhou X, Zhao A.   +6 more
europepmc   +2 more sources

In vitro virucidal activity of chemical compounds against porcine transmissible gastroenteritis virus and porcine respiratory coronavirus. [PDF]

BMC Vet Res
Porcine transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV) are enveloped, single-stranded RNA viruses belonging to the genus Alphacoronavirus in the family Coronaviridae.
Antas M, Olech M.
europepmc   +2 more sources

Development of a ferritin-based subunit nanoparticle vaccine targeting the S-RBD of porcine transmissible gastroenteritis virus. [PDF]

Front Vet Sci
Porcine transmissible gastroenteritis virus (TGEV) remains a critical economic threat to the global swine industry due to its near 100% mortality rate in newborn piglets within 5 days of age; however, current vaccine strategies, such as attenuated ...
Nie N, Yan H, Zhang L, Qian Y, Zhu S, Jung YS, Cao S.   +6 more
europepmc   +2 more sources

Evaluating the Immunogenicity of a Recombinant Bacillus subtilis Expressing LTB-Fused Protective Antigen of Transmissible Gastroenteritis Virus in a Murine Model. [PDF]

Biology (Basel)
Simple Summary Transmissible gastroenteritis is a severe intestinal disease that causes high mortality in newborn piglets, leading to major economic losses in the swine industry worldwide.
Fan R, Bi Y, Yang S, Yao S, An W, Wang Z, Ma Z, Rui P, Song T, Wang L, Li F.   +10 more
europepmc   +2 more sources

A novel linear B-cell epitope on S2 protein of transmissible gastroenteritis virus identified using a monoclonal antibody. [PDF]

BMC Vet Res
Transmissible gastroenteritis virus (TGEV) is a devastating coronavirus that causes severe gastrointestinal symptoms and high mortality in piglets, resulting in substantial economic losses in the swine industry. The spike (S) protein, particularly its S2
Hou J, Hou R, Lu H, Yu Y, Zhao R, Shi Z, Lv Y, Liu J, Wang S, Yuan J, Shi C, Hu H.   +11 more
europepmc   +2 more sources

Mechanism by which porcine transmissible gastroenteritis virus disrupts host innate immunity. [PDF]

Front Immunol
Innate immune evasion is a critical aspect of viral infections, as it disrupts the host’s defense mechanisms.The innate immune system, as the primary defense against pathogens, detects pathogen-associated molecular patterns (PAMPs) via pattern ...
Wang Z, Xie J, Li Q, Liu Y, Zhang X, Mi E, Wang L, Wang L, Zhang F.   +8 more
europepmc   +2 more sources

Discovery of Cetaben as a Novel Antiviral Agent Against Porcine Epidemic Diarrhea Virus From a Cholesterol-Lowering Compound Library. [PDF]

Transbound Emerg Dis
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such treatments.
Li Y, Qin P, Zhang K, Ma N, Wang T, Chen Z, Yuan Y, Li D, Yu L, Li W, Du W, Li Y.   +11 more
europepmc   +2 more sources

Proteome Profile of Swine Testicular Cells Infected with Porcine Transmissible Gastroenteritis Coronavirus

PLoS ONE, 2014
The interactions occurring between a virus and a host cell during a viral infection are complex. The purpose of this paper was to analyze altered cellular protein levels in porcine transmissible gastroenteritis coronavirus (TGEV)-infected swine testicular (ST) cells in order to determine potential virus-host interactions.
Ruili Ma, Yanming Zhang, Haiquan Liu, Pengbo Ning   +3 more
openaire   +5 more sources

Historical Evolutionary Dynamics and Phylogeography Analysis of Transmissible Gastroenteritis Virus and Porcine Deltacoronavirus: Findings from 59 Suspected Swine Viral Samples from China

International Journal of Molecular Sciences, 2022
Since the beginning of the 21st century, humans have experienced three coronavirus pandemics, all of which were transmitted to humans via animals.
Quanhui Yan, Keke Wu, Weijun Zeng, S. Yu, Yuwan Li, Yawei Sun, Xiaodi Liu, Yang Ruan, Juncong Huang, Hongxing Ding, Lin Yi, Mingqiu Zhao, Jinding Chen, Shuangqi Fan   +13 more
semanticscholar   +1 more source