Results 41 to 50 of about 94,099 (224)

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

Allergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas, Inmaculada Martinez‐Saguer, Konrad Bork, Anastasios E. Germenis, Anete S. Grumach, Hanga Réka Horváth, Andrea Luczay, Andrea Zanichelli, Markus Magerl, Stephen Betschel, Emel Aygören‐Pürsün, Jonathan A. Bernstein, Isabelle Boccon‐Gibod, Teresa Caballero, Mauro Cancian, Sandra Christiansen, Danny M. Cohn, Francisco Contreras, Sansanee Craig, Camelia Isaic, Ankur Jindal, Constance H. Katelaris, Hilary J. Longhurst, Andrew MacGinnitie, Jonny Peter, Grzegorz Porebski, Avner Reshef, Dinh Van Nguyen, Bruce Zuraw, Anthony J. Castaldo, Henrik Balle Boysen, Timothy Craig, the Hereditary Angioedema Working Group (HAWK Group), Adil Adatia, Fiorella Adrianzen, Shimalee Andarawewa, Sladjana Andrejevic, Gabriel Emmanuel Arce‐Estrada, Ecem Ay, Adil Bahadir, Noemi Anna Bara, Marko Barešić, Krasimira Baynova, Shira Benor, Juliette Besson, Dharmagat Bhattarai, Patricia Bigas, Alexis Bocquet, Laurence Bouillet, Nicholas Brodszki, Thomas Buttgereit, Rosario Cabañas, Regis Campos, Asuman Çamyar, Orlane Chol, Stefan Cimbollek, Monica Colque Bayona, Cascia Day, Mats de Lange, Alex Fam, Davide Firinu, Tomas Freiberger, Johana Gil‐Serrano, Delphine Gobert, Dawn Goodyear, Maria del Mar Guilarte Clavero, Svetlana Hadvabova, David Hagin, Roman Hakl, George Harmat, Mensuda Hasanhodzic, Gocki Jacek, Joshua Jacobs, Rashmi Jain, Milos Jesenak, Amin Kanani, Daniela Kapustová, Boris Karanovic, Paul Keith, Tamar Kinaciyan, Pavlina Kralickova, Marcin Kurowski, Krzysztof Kuziemski, Rolando Laurel‐Laurel, Iris Leibovich‐Nassi, Gabriela Leon Zambrana, Ramon Lleonart, Lorena Lorenzo, Ferhat Maksudov, Ania Manson, Dusanka Markovic, Jayne McGucken, Nihal Mete Gokmen, Radovan Mijanovic, Vania Maria Miranda Saavedra, Irene Modestou, Sandra Nieto, Nora Nilsson, Patrik Nordenfelt, Francesca Perego, Angelica Petraroli, Elsa Phillips‐Angles, Alicia Prieto‐García, Michel Raguet, Marc Riedl, Matija Rijavec, Solange Rodrigues Valle, Yaryna Romanyshyn, Antoine Saut, Riccardo Senter, Branislav Šlenker, Marta Sobotkova, Peter J. Spaeth, Marcin Stobiecki, Linda Sundler Björkman, Mireille‐Maria Suttle, Agnes Szilágyi, Paola Triggianese, Kassiani Tzeli, Martina Vachová, Anna Valerieva, Solange Valle, Lilian Varga, Walter A. Wuillemin, Patrick Yong, Zhi Yuxiang, Liudmyla Zabrodska, Radana Zachova, Julia Zharankova   +128 more
wiley   +1 more source

A vaccination programme combining a live attenuated Salmonella Typhimurium and an autogenous inactivated Salmonella Enteritidis vaccine confers protection and reduces ovarian colonisation with the Salmonella Enteritidis isolate 7A, PT12

Australian Veterinary Journal, EarlyView.
Salmonella enterica serovar Enteritidis (SE) can colonise chicken ovaries and contaminate eggs, posing a global risk of human gastroenteritis, often linked to raw or undercooked eggs. Control options for SE outbreaks in Australia are limited; autogenous SE vaccines are commonly used, while live attenuated Salmonella Typhimurium (ST) vaccines are ...
JA Quinteros, TB Wilson, A Anwar, T Scott, P Shil, AH Noormohammadi, G Underwood, PC Scott   +7 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Whole‐Genome Characterization of Rare Artiodactyl‐Like G10P [14] and G8P [14] Rotavirus a Strains Detected in Pediatric Gastroenteritis Cases in Hokkaido Prefecture, Japan [PDF]

J Med Virol
ABSTRACT Rotavirus alphagastroenteritidis (RVA) is the leading cause of acute gastroenteritis in young children worldwide, as well as in a wide range of animal species. In 2020 and 2022, we identified three unusual RVA strains in pediatric gastroenteritis patients in Hokkaido Prefecture, Japan, using next‐generation sequencing: one G10P[14] strain ...
Takebayashi A, Fukuda Y, Fujii Y, Nihira H, Kihara M, Kudou Y, Adachi S, Shintani N, Tsugawa T.   +8 more
europepmc   +2 more sources

Increase of GII.17 Norovirus Infections During the 2024-2025 Season in Multiple Cities, China. [PDF]

J Med Virol
ABSTRACT A significant numerical increase of genotype GII.17 norovirus‐associated sporadic infections was observed in multiple cities in China during the 2024–2025 season. We collected fecal samples from hospitalized children with acute gastroenteritis from 29 sentinel hospitals nationwide to screen for norovirus.
Zheng W, Mu X, Wang S, Qiu T, Wang X.
europepmc   +2 more sources

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, EarlyView.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source

‘The Heart of the Matter’: Grandparent Childcare in Contemporary Chinese Families

Children &Society, EarlyView.
ABSTRACT Grandparent childcare is an international phenomenon, especially within families with children under 3 years old. China is no exception, as shown by a number of quantitative studies. Less clear is our understanding of the actual childcare arrangements involved and how these are negotiated and sustained through the intergenerational ...
Jiatong Ling, Lorna Montgomery, John Pinkerton   +2 more
wiley   +1 more source

Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram, Marine Corbin, Andrea ’t Mannetje, Jeroen Douwes, Amanda Kvalsvig, Amanda Eng   +5 more
wiley   +1 more source

Duodenal stricture and portal gas accumulation secondary to ulcerative, fibronecrotising duodenitis in a foal

Equine Veterinary Education, EarlyView.
Summary Gastroduodenal ulcer disease with secondary stricture formation of the proximal duodenum and portal gas accumulation is described in a neonatal foal. Conventional diagnostics were performed to reach a diagnosis, including gastroscopy, ultrasonography and positive contrast radiography. In addition, a post‐mortem CT was acquired with the contrast
R. F. Dash, G. Manso‐Diaz, A. Suarez‐Bonnet, M. Hewetson   +3 more
wiley   +1 more source

Missed opportunities to prevent HIV acquisition with pre‐exposure prophylaxis: A mixed methods study of people with recently acquired HIV in the United Kingdom

HIV Medicine, EarlyView.
Abstract Objectives To explore missed opportunities for PrEP use among people with recently acquired HIV in the United Kingdom. Methods Data were derived from CASCADE, an international, longitudinal, mixed‐methods study of adults (≥16 years) with recently acquired HIV (≤12 months).
Argyro Karakosta, Emily Jay Nicholls, Flavien Coukan, Diarmuid Nugent, Iain Reeves, Laura Waters, Sarah Fidler, Elisa Ruiz Burga, Julie Fox, Alison Uriel, Jane Nicholls, Claire Mackintosh, Shema Tariq, Fiona Burns, for CASCADE Collaboration, John Gill, Kholoud Porter, Fiona Burns, Christina Carlander, Rafael Eduardo Campo, Harmony Garges, Sophie Grabar, Inma Jarrín, Laurence Meyer, Moustafa Kamel, Shema Tariq, Giota Touloumi, Marc van der Valk, Vani Vannappagari, Alain Volny Anne, Linda Wittkop, Lital Young, Agnes Aisam, Diana Barger, Eli Fitzgerald, Argyro Karakosta, Emily Jay Nicholls, Nicoletta Policek, Bruno Spire, Inés Suárez‐García, Sophie Abgrall, Valerie Andriantsoanirina, Veronique Avettand‐Fenoel, Christine Bourgeois, Marie‐Laure Chaix, Antoine Cheret, Hugues Fischer, Cecile Goujard, Caroline Lascoux‐Combe, Annie Le Palec, Ventzlislava Petrov‐Sanchez, Asier Saez‐Cirion, Remonie Seng, Karl Stefic, Josephine Tine, E Piet, A Gagneux‐Brunon, C Jacomet, L Piroth, F Benezit, M Goussef, P Tattevin, F Bani Sadr, I Lamaury, M Nacher, H Bazus, O Robineau, R Calin, C Katlama, JL Meynard, B Denis, J Ghosn, V Joly, MA Khuong, F Caby, E Rouveix Nordon, P de Truchis, S Abgrall, A Chéret, C Duvivier, A Becker, P Miailhes, S Abel, G Unal, A Makinson, G Martin‐Blondel, A Morisot, S Bregigeon, C Allavena, V Rabier, H Fischer, L Vallet, L Marchand, T Saïdi, D Costagliola, S Grabar, Pierre Tattevin, Pierre de Truchis, M Hughes Fischer, Santiago Moreno, David Dalmau, M Luisa Navarro, M Isabel González, Federico Garcia, Eva Poveda, Félix Gutiérrez, Rafael Rubio, Francesc Vidal, Juan Berenguer, Juan González, M Ángeles Muñoz‐Fernández, G. Adamis, M. Chini, G. Chrysos, M. Marangos, O. Katsarou, D. Kofteridis, S. Metallidis, P. Panagopoulos, N. Pantazis, A. Papadopoulos, V. Paparizos, V. Papastamopoulos, M. Psychogiou, H. Sambatakou, NV. Sipsas, G. Touloumi, C Thomadakis, Julie Fox, Louise Terry, Alison Uriel, Sarah Fidler, Wilbert Ayap, Laura Waters, Fowsiya Nur, Sabine Kinloch, Thomas Fernandez, Diarmuid Nugent, Javier Pinedo, Iain Reeves, Lidia Ignatov, Tracy Fong, Laura Cunningham, Jaydee Pangan, Claire Mackintosh, Louise Sharp   +145 more
wiley   +1 more source