Results 61 to 70 of about 97,084 (281)

The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost

open access: yesJournal of Infection in Developing Countries, 2016
Introduction: In this study, the goal was to evaluate the impact of nosocomial rotavirus gastroenteritis in pediatric patients by determining the incidence of nosocomial rotavirus gastroenteritis, the resulting duration of hospital stay, and direct cost.
Özlem O Gundeslioglu   +4 more
doaj   +1 more source

Pharmacokinetics and Bioequivalence of a Novel Extended‐Release Formulation of Methylphenidate Hydrochloride for Attention‐Deficit/Hyperactivity Disorder

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Extended‐release (ER) formulations of the stimulant methylphenidate are commonly used to treat attention‐deficit/hyperactivity disorder in both children and adults. Previous studies have shown that the clinical effectiveness of long‐acting methylphenidate formulations is closely tied to the drug's pharmacokinetic (PK) profile, highlighting the
Ann C. Childress   +2 more
wiley   +1 more source

Triple Intergenotype Recombination of Human Astrovirus 5, Human Astrovirus 8, and Human Astrovirus 1 in the Open Reading Frame 1a, Open Reading Frame 1b, and Open Reading Frame 2 Regions of the Human Astrovirus Genome

open access: yesMicrobiology Spectrum, 2023
Human astrovirus (HAstV) strains exhibit high levels of genetic diversity, and many recombinant strains with different recombination patterns have been reported. The aims of the present study were to investigate the emergence of HAstV recombinant strains
Hongyu Wei   +9 more
doaj   +1 more source

Integrated In Silico – In Vitro Study Investigating Dipeptides as Chorismate Synthase Modulators: Spotlight on Its Mechanism of Action

open access: yesGlobal Challenges, EarlyView.
This study integrates computational and experimental approaches to explore how short dipeptides modulate the activity of chorismate synthase. Unexpectedly, the GluAsp dipeptide enhanced enzyme activity by promoting a transient surface channel near the active site, possibly revealing a new structural feature relevant for microbial metabolism and ...
Lorenzo Pedroni   +4 more
wiley   +1 more source

Coping with the burden of irritable bowel syndrome by emotional suppression—A cross sectional observational pilot study

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract Background Psychological stress like depression, anxiety, and anger is a common comorbidity of irritable bowel syndrome (IBS). This clinical pilot study aimed to investigate if individuals employ emotional suppression to cope with the psychological burden associated with IBS.
Henning Sommermeyer   +5 more
wiley   +1 more source

Things We Do for No Reason™: Routinely maintaining intravenous access in hospitalized patients

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Peripheral intravenous catheters (PIVCs) are widely used in hospitalized patients and are often maintained even after the need for intravenous therapy has resolved. This article challenges the routine practice of maintaining idle PIVCs in clinically stable patients.
Brent Kennis   +2 more
wiley   +1 more source

Recurrent Septic Shock in Immunosuppressed Patients. [PDF]

open access: yesClin Case Rep
ABSTRACT Cytomegalovirus gastroenteritis presents with diarrhea and abdominal pain in immunosuppressed patients, and histopathological examination is essential by endoscopy. This case illustrates that cytomegalovirus enteritis may develop insidiously and possibly invoke shock in immunocompromised patients, warranting its inclusion in the differential ...
Fukushima S, Fujita K, Hagiya H.
europepmc   +2 more sources

Immunological effects of alpha‐lactalbumin‐enriched low‐protein infant formula: A randomized controlled trial

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Breast‐fed (BF) have lower risk of infections during infancy compared to those formula‐fed (FF). A higher content of alpha‐lactalbumin (α‐lac) in breast milk, which may promote a more favorable gut microbiota, could be one reason.
Ulrika T. Nilsson   +7 more
wiley   +1 more source

Odevixibat after liver transplant in patients with progressive familial intrahepatic cholestasis type 1: A case series

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Patients with progressive familial intrahepatic cholestasis type 1 (PFIC1) who have undergone liver transplantation (LT) may have unmet needs and impacts on daily life due to post‐LT complications, including diarrhea and hepatic steatosis.
Georg‐Friedrich Vogel   +13 more
wiley   +1 more source

First description of gastroenteritis viruses in Lebanese children: A pilot study

open access: yesJournal of Infection and Public Health, 2011
Summary: Human enteric viruses are important causes of acute gastroenteritis in infants and children. The role of rotaviruses, adenoviruses, human caliciviruses and astroviruses in the development of severe acute gastroenteritis requiring hospitalization
Randa Meraabi Al-Ali   +5 more
doaj   +1 more source

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