Results 121 to 130 of about 22,278 (237)

Meta‐Analysis: Prevalence of Non‐Helicobacter pylori, Non‐NSAID Peptic Ulcer Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
A meta‐analysis of 92 studies including 60,816 patients found that non‐H. pylori, non‐NSAID represent a non‐negligible but heterogeneous component of peptic ulcer disease. Among bleeding ulcers, this proportion increased over time, potentially reflecting evolving etiologic patterns beyond H. pylori infection and NSAID exposure.
Jun Watanabe   +9 more
wiley   +1 more source

Organ‐Specific Cancer‐Associated Fibroblast Subtypes Across the Digestive System Linked to Cancer Hallmarks

open access: yesCancer Science, EarlyView.
We integrated 14 single‐cell RNA‐seq datasets and 18 bulk cohorts to define eight CAF subtypes in GI cancers. myCAF1 and myCAF2 promoted immunosuppressive, poor‐prognosis niches, whereas iCAF1 was linked to favorable prognosis and antitumor immunity.
Huaitao Wang   +7 more
wiley   +1 more source

Bile‐Derived Exosomal miR‐196a/‐196b as Diagnostic Biomarkers Associated With Tumor Progression in Biliary Tract Cancer

open access: yesCancer Science, EarlyView.
Bile‐derived exosomal miR‐196a and miR‐196b are identified as novel biomarkers for biliary tract cancer. Serum miR‐196a levels are significantly elevated in advanced disease with metastasis, while both miRNAs contribute to tumor progression by promoting cancer cell proliferation and invasion.
Naotaka Kugiyama   +20 more
wiley   +1 more source

Decreased Expression by a Chemically Modified siRNA to PTBP1 Seriously Affects Warburg Effect in Colorectal Cancer Cells

open access: yesCancer Science, EarlyView.
Chemically modified siR‐PTBP1 disrupts the Warburg effect by reprogramming pyruvate kinase splicing from PKM2 to PKM1. This metabolic shift activates the TCA cycle, increases ATP production, and excessive ROS generation, and ultimately induces apoptotic cell death in colorectal cancer cells.
Keita Matsumoto   +19 more
wiley   +1 more source

User satisfaction with fingerstick versus continuous glucose monitoring in surgical wards: A two‐centre non‐randomised clinical trial

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims To compare person‐reported outcomes on point‐of‐care (POC) fingerstick glucose monitoring (FSGM) with POC continuous glucose monitoring systems (CGMS) in adults admitted to surgical wards. The primary outcome was convenience; the secondary outcome was satisfaction with diabetes‐related treatment.
Tine Lumbye Thomsen   +6 more
wiley   +1 more source

[Lack of specialists in gastroenterological surgery].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1997
Despite the fact that a prognosis in 1991 predicted a surplus of ten gastroenterological surgeons in 1994, several hospitals are now experiencing a lack of applicants. In order to define the scope of this problem, the Norwegian Gastroenterological Society and The Specialty Committee for Gastroenterological Surgery sent a questionnaire and made a ...
E, Schlichting, J H, Solhaug
openaire   +1 more source

AI and Epigenetics: A New Opportunity for Early Pancreatic Cancer Detection in Australia

open access: yes
ANZ Journal of Surgery, EarlyView.
Jaswinder S. Samra   +2 more
wiley   +1 more source

Seventh Åland Island Meeting on von Willebrand Disease

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The seventh Åland Island Meeting on von Willebrand Disease (VWD) was held on the Åland archipelago in Finland, from 26 to 28 September 2024. Aim The meeting brought together experts in the field of VWD from around the world to share the latest advances and knowledge in VWD.
Riitta Lassila   +17 more
wiley   +1 more source

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