Results 221 to 230 of about 552,178 (258)

Early Endoscopic Repair of Traumatic Skull Base Dural Injuries: Challenging the Dogma of Conservative Management

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Traditional management of traumatic skull base dural injury has often favored observation and conservative therapy, despite the risk of delayed intracranial complications. This paradigm originated when operative intervention required craniotomy and carried significant morbidity.
Jessica W. Grayson, Madeline P. Bald, Lauren McLeod, Adam J. Skelton, Nicolaus D. Knight, Do‐Yeon Cho, Justin Turner, Hari Jeyarajan, Kristen O. Riley, Bradford A. Woodworth   +9 more
wiley   +1 more source

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber, Manuel Lasch, Veronika Volgger, Clemens Stihl, Philipp Teupe, Fabienne Oettgen, Sophia Gantner, Moritz Gröger   +7 more
wiley   +1 more source

EUS-Guided Choledochoduodenostomy With Lumen-Apposing Metal Stents: A Recommendation From an Expert Delphi Consensus. [PDF]

United European Gastroenterol J
Khoury T, Sbeit W, Fusaroli P, Do-Cong Pham K, Bronswijk M, Mangiavillano B, Leblanc S, Lakhtakia S, Jacques J, Robles-Medranda C, Yuen Bun Teoh A, Vanella G, Ilie Orzan R, Spadaccini M, Tarantino I, Anderloni A, Hassan C, Siersema P, Kahaleh M, Fabbri C, Binda C, Perez-Miranda M, van Wanrooij RLJ, Fumex F, Gincul R, Facciorusso A, Van der Merwe S, Arcidiacono PG, Kunda R, Crinò SF, Deprez PH, Lisotti A, Napoléon B.   +32 more
europepmc   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang, Xin‐Yu Ding, Mei‐Ping Lu, Yan‐Bing Chen, Ye Yuan, Lin Jiang, Min Zhang, Lei Cheng   +7 more
wiley   +1 more source

Shaping the research agenda of pediatric gastroenterology, hepatology, and nutrition: The proposal from a SIGENP expert groups. [PDF]

JPGN Rep
Agostoni C, Alberti D, Auricchio R, Baldassarre ME, Borrelli O, Bramuzzo M, Capriati T, Catassi C, Cenni S, Crocco M, Cucchiara S, Dall'Oglio L, Angelis P, Saccomani MD, Dato FD, Giorgio AD, Diamanti A, Dipasquale V, Felici E, Francavilla R, Giorgio V, Greco L, Lorio R, Labriola F, Lionetti P, Lionetti E, Maggiore G, Malamisura M, Mandato C, Marseglia A, Nicastro E, Norsa L, Oliva S, Pensabene L, Pieri ES, Quitadamo P, Ranucci G, Renzo S, Romano C, Salvatore S, Scarallo L, Spagnuolo MI, Staiano A, Strisciuglio C, Tambucci R, Troncone R, Vajro P.   +46 more
europepmc   +1 more source

Development and Reliability Testing of the Sinonasal Assessment of Reepithelialization, a Novel Wound Healing Scale to Assess Postoperative Healing

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinus and skull base surgery create areas of demucosalized bone and cartilage in the sinonasal cavity, yet no standardized system exists to describe the progressive healing of these wounds. The goal of this study was to develop the novel Sinonasal Assessment of Reepithelialization (SNARE) and perform parametric testing including ...
Rohan Bellary, Zakaria Dairi, Niraj Rama, Jennifer Kreinik, Thomas S. Higgins, Taylor Carle, Arthur W. Wu, Dilpreet Mann, Jennifer K. Mulligan, Brian Lobo, Christopher Ito, Elisa A. Illing, Satyan B. Sreenath, Martin J. Citardi, Christopher Roxbury, Raj Sindwani, Edward McCoul, Jeffrey Suh, Daniel Beswick, Philip G. Chen, Dennis M. Tang   +20 more
wiley   +1 more source

Endoscopic submucosal dissection for a colorectal tumor with coexisting muscle-retracting sign and underlying diverticulum: the first reported case. [PDF]

Oxf Med Case Reports
Yoshimoto T, Matsuyama D, Nakanishi A, Nakatani K, Nagakura K, Ishii H, Takihara H.   +6 more
europepmc   +1 more source

Impact of Highly Effective Modulator Therapy on Olfactory‐Specific Gene Expression in People With Cystic Fibrosis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis is common in people with cystic fibrosis (PwCF). Highly effective modulator therapy (HEMT) has been shown to improve sinonasal outcomes. However, prior studies failed to show improvement in objective olfaction with HEMT, and the impact of HEMT on olfactory‐specific quality of life has yet to be studied ...
Michael R. Xiang, Ankit Chauhan, Gina Hong, Denis Hadjiliadis, Daniel Dorgan, Michael M. Rey, Samantha Kane, James N. Palmer, Nithin D. Adappa, Noam A. Cohen, Michael A. Kohanski, Jennifer E. Douglas   +11 more
wiley   +1 more source

A Multicenter, Prospective Real-World Study of Simethicone-Activated Charcoal in Patients With Persistent Dyspeptic Symptoms Despite Acid Suppression (SIMAC Study). [PDF]

JGH Open
Kumar A, Sreenivas DV, Behera SK, Rao GRS, Kumar GSS, Chatterjee JG, Choudhary NK, Bagepally RS, Puri S, Rizvi SMA, Pathak R, Pal S.   +11 more
europepmc   +1 more source

Biologics Adoption in CRSwNP and the Associated Decline in Endoscopic Sinus Surgery: A Longitudinal Claims Database Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Biologic treatments were introduced for chronic rhinosinusitis with nasal polyps (CRSwNP) in 2019. Treatment algorithms for medically refractory CRSwNP remain open, with patients choosing among surgery, biologics, or both. Real‐world utilization of surgery and biologics remains incompletely characterized.
Stephanie Shintani Smith, Sam L. Kaefer, Harsh Duvvuru, Robert C. Kern, Brent A. Senior, Vijay R. Ramakrishnan   +5 more
wiley   +1 more source