Results 181 to 190 of about 55,081 (249)

Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum

open access: yesArthritis &Rheumatology, Volume 78, Issue 8, Page 1731-1740, August 2026.
Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig   +5 more
wiley   +1 more source

The integration of the British Pharmacological Society's prescription safety assessment into the WHO 6‐step model of rational pharmacotherapy in a Turkish medical school

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2465-2473, August 2026.
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez   +2 more
wiley   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1877-1903, August 2026.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

Early‐Onset Gastric Cancer as a High‐Risk Disease Entity in the United States: Clinicopathologic Features, Regional Variation, and Outcomes

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Introduction Early‐onset gastric cancer (EOGC), defined as diagnosis before age 45, represents a distinct and increasingly recognized subset of gastric cancer. Emerging evidence suggests that clinical behavior, treatment patterns, and outcomes differ from average‐onset disease, yet these differences remain incompletely characterized.
Dani R. Castillo   +12 more
wiley   +1 more source

Expert Treatment Considerations for Lower Face and Neck Rejuvenation

open access: yesDermatological Reviews, Volume 7, Issue 4, August 2026.
ABSTRACT Background The lower face and neck are essential to overall facial harmony and a balanced appearance. Although most nonsurgical treatments have focused on the upper and midface, a variety of minimally invasive options are now available for treating the lower face and neck that target different aesthetic concerns and provide welcome ...
Sabrina Fabi   +6 more
wiley   +1 more source

Unveiling sleep disturbances in KCNB1‐related disorders: Insights from a cohort of 78 individuals

open access: yesEpilepsia Open, Volume 11, Issue 4, Page 1159-1170, August 2026.
Abstract Objectives Sleep disturbances are frequent comorbidities in epilepsies and developmental encephalopathies. This study aimed to characterize sleep abnormalities in individuals with KCNB1‐related disorders, focusing on their prevalence, clinical manifestations, and impact on daily functioning.
Giovanna Scorrano   +4 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Risk of Depressive Symptoms in Older Adults

open access: yesInternational Journal of Geriatric Psychiatry, Volume 41, Issue 8, August 2026.
ABSTRACT Introduction There is a potential link between Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) and depression in later life. This study aims to examine whether MASLD is associated with elevated clinically relevant depressive symptoms in community‐dwelling older adults.
Marzieh Nasr Azadani   +12 more
wiley   +1 more source

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