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Gastroesophageal Reflux Disease
Journal of Clinical Gastroenterology, 2004Although Galen first described esophagitis almost 2000 years ago, its relation to acid was only recognized in the 19th century by Rokitansky. Considerably more interest in the symptoms and complications of esophagitis has been evident over the last century, as gastroesophageal reflux disease displaced peptic ulceration and became the principal acid ...
Irvin M. Modlin +3 more
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Prevalence of gastroesophageal reflux disease and gastroesophageal reflux disease symptoms in Japan
Journal of Gastroenterology and Hepatology, 2005AbstractBackground and Aim: Epidemiological studies have shown that 10–48% of people in developed countries have gastroesophageal reflux disease (GERD) symptoms such as heartburn and acid regurgitation. The present study aimed to examine the prevalence of GERD symptoms and GERD in Japanese subjects.Methods: A cross‐sectional study of Japanese ...
Toshio Watanabe +9 more
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Pathogenesis of gastroesophageal reflux disease
Gastroenterology Clinics of North America, 2002The pathophysiology of reflux esophagitis involves contact of the esophageal epithelium with acid-pepsin in the refluxate. For this contact to occur with sufficient duration, there must either be a combination of defects in antireflux and luminal clearance mechanisms for acid-pepsin to overwhelm a previously healthy epithelium or primary defects within
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Gastroesophageal Reflux Disease
The American Journal of Nursing, 2000_ ~~~inappropriately GERD may be unaware of its potential danger. GERD is the most prevalent of the acid-related disorders, which also include dyspepsia, gastritis, and peptic ulcer disease. A cost analysis by Levin and colleagues revealed that the condition is prevalent in 2.9% of HMO patients and leads to an annual cost of $471 per person.
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Gastroesophageal Reflux Disease
Annals of Internal MedicineGastroesophageal reflux disease (GERD) is a condition that occurs when reflux of gastric contents into the esophagus causes symptoms and/or complications. The prevalence of GERD in Western societies has been estimated at 30%, making it one of the most commonly encountered disorders in primary care.
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Gastroesophageal Reflux Disease [PDF]
New England Journal of Medicine, 2009 Guillermo Ruiz-Irastorza +2 more
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An Overview of Gastroesophageal Reflux Disease
2018Gastroesophageal reflux disease (GORD) is a chronic disorder that is caused by abnormal reflux. It is associated with prolonged exposure of the distal oesophagus and extra oesophageal airways to gastric contents and leads to cardinal symptoms and/or findings, which affect patient quality of life [1].
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