Results 221 to 230 of about 4,376,164 (395)

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

Morbidity, mortality, and health outcomes following emergency department visits for fentanyl-related overdoses: A retrospective cohort study. [PDF]

Drug Alcohol Depend Rep
Choo LY, Nash S, Farmer B, Mallow Z, Miller LE, Six-Workman EA, Mahoney JJ, Winstanley EL.   +7 more
europepmc   +1 more source

P218 Over 30% of active flares in inflammatory bowel disease patients are associated with gastrointestinal infectious agents [PDF]

, 2018
Julajak Limsrivilai, Zachary M. Saleh, Laura A. Johnson, Ryan W. Stidham, Akbar K. Waljee, Brian Gutermuth, Shail M. Govani, Andrew Brown, Emily Briggs, Krishna Rao, Peter Higgins   +10 more
openalex   +1 more source

Risk of oral and gastrointestinal mucosal injury among patients receiving selected targeted agents: a meta-analysis

Supportive Care in Cancer, 2013
L. Elting, Yu-Chia Chang, Pratibha P Parelkar, C. Boers-Doets, M. Michelet, Guido Hita, T. Rouleau, C. Cooksley, J. Halm, Madhuri V. Vithala, P. Bossi, C. Escalante, M. Brennan, O. B. O. T. S. S. O. M. Oncology   +13 more
semanticscholar   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Associations of oral hypoglycemic use, fruit intake, and diabetes duration with gastrointestinal autonomic dysfunction in type 2 diabetes patients in Zanzibar. [PDF]

Sci Rep
Haji HT, Ebrahim A, Khamis AG, Ali RM, Ramaiya K, Mashili FL.   +5 more
europepmc   +1 more source

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Nature Medicine, 2017
P. M. Bruno, Yunpeng Liu, Ga-Young Park, J. Murai, C. Koch, Timothy J. Eisen, J. Pritchard, Y. Pommier, S. Lippard, M. Hemann   +9 more
semanticscholar   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Basidiobolus ranarum as an Etiologic Agent of Gastrointestinal Zygomycosis

, 2001
Z. U. Khan, Mousa Khoursheed, Rosemary Makar, Salah Al-Waheeb, Ibtisam Al‐Bader, Anwar AlMuzaini, Rachel Chandy, Abu Salim Mustafa   +7 more
openalex   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source