Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database. [PDF]
IntroductionLiver fibrosis is a pathological condition in response to chronic liver injuries. Currently, there is no Food and Drug Administration (FDA) approved pharmacotherapy for liver fibrosis.
Liu Y, Zhao X, Wang X, Zhou Q.
europepmc +2 more sources
Clinical Practice Guideline for the Management of Antithrombotic Agents in Patients Undergoing Gastrointestinal Endoscopy [PDF]
Antithrombotic agents, including antiplatelet agents and anticoagulants, are increasingly used in South Korea. The management of patients using antithrombotic agents and requiring gastrointestinal endoscopy is an important clinical challenge.
Hyun Lim+11 more
doaj +3 more sources
Current and emerging anti-angiogenic therapies in gastrointestinal and hepatobiliary cancers
Gastrointestinal tumours are a heterogeneous group of neoplasms that arise in the gastrointestinal tract and hepatobiliary system. Their incidence is rising globally and they currently represent the leading cause of cancer-related mortality worldwide ...
Nadia Saoudi González+4 more
doaj +1 more source
The Challenge of Applications of Probiotics in Gastrointestinal Diseases
Gastrointestinal disease is characterized by gastrointestinal dysfunction with dysbiosis of the microbiome. Probiotics may act as biological agents in treating gastrointestinal diseases through modifying gut microbiota.
William Wolfe+9 more
semanticscholar +1 more source
Colo‐appendico‐duodenal fistula: Rare presentation of extrapulmonary tuberculosis
A colo‐appendico‐duodenal fistula is a rare occurrence that results from extrapulmonary tuberculosis (TB) complications, especially in the endemic region.
David Eng Yeow Gan+3 more
doaj +1 more source
High Spatial and Temporal Resolution NIR-IIb Gastrointestinal Imaging in Mice [PDF]
Conventional biomedical imaging modalities, including endoscopy, X-rays, and magnetic resonance, are invasive and cannot provide sufficient spatial and temporal resolutions for regular imaging of gastrointestinal (GI) tract to guide prognosis and therapy of GI diseases. Here we report a non-invasive method for optical imaging of GI tract.
arxiv +1 more source
Management of Patients With Acute Lower Gastrointestinal Bleeding: An Updated ACG Guideline.
Acute lower gastrointestinal bleeding (LGIB) is a common reason for hospitalization in the United States and is associated with significant utilization of hospital resources, as well as considerable morbidity and mortality.
N. Sengupta+6 more
semanticscholar +1 more source
Background and Objectives: A novel synthetic self-assembling peptide, PuraStat, has been introduced as a hemostatic agent. This case series aimed to evaluate the clinical efficacy of PuraStat for gastrointestinal bleeding during emergency endoscopy ...
Takashi Murakami+7 more
doaj +1 more source
Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko+6 more
core +1 more source
Prevotella is recognized as one of the core anaerobic genera in the oral microbiome. In addition, members of this genus belong to microbial communities of the gastrointestinal and respiratory tracts. Several novel Prevotella species, most of them of oral
E. Könönen, U. Gursoy
semanticscholar +1 more source