Results 111 to 120 of about 4,823,404 (316)

Asian consensus guidelines for the diagnosis and management of gastrointestinal stromal tumor

, 2016
[[abstract]]Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors originating in the gastrointestinal tract. With the introduction of molecular-targeted therapy for GISTs which has yielded remarkable outcomes, these tumors have ...
Koo, DH;Ryu, MH;Kim, KM;Yang, HK;Sawaki, A;Hirota, S;Zheng, J;Zhang, B;Tzen, CY;Yeh, CN;Nishida, T;Shen, L;Chen, LT;Kang, YK
core   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

UNLABELLED: Analysis of DNA methylation is a valuable tool to understand disease progression and is increasingly being used to create diagnostic and prognostic clinical biomarkers.
Sjöström, M, Ning, Y, Witte, ON, Boutros, PC, Huang, FW, Perry, MD, Gleave, M, Zwart, W, Shrestha, R, Phillips, T, Maher, CA, He, HH, Aggarwal, R, Fraser, M, Petricca, J, Small, EJ, Quigley, DA, Bjartell, A, Ye, W, Morgans, AK, Ashworth, A, Maurice-Dror, C, Ng, SWS, Moreno-Rodriguez, T, Haffner, MC, Levy, S, Beer, TM, Gilbert, LA, Zhao, SG, Fong, L, Rettig, MB, Annala, M, Bose, R, He, C, Lloyd, P, Mahajan, NP, Cui, X-L, McCarthy, E, Chou, J, Hua, JT, Evans, CP, Feng, FY, Li, H, Chen, S, Chen, WS, Foye, A, Zoubeidi, A, Chi, KN, Lang, JM, Bergamaschi, A, Chesner, L, Tran, PT, Lundberg, A, Herberts, C, Posadas, EM, Wyatt, AW, Luo, J, Maheshwari, A, Zhang, M, Thomas, GV, Huang, J, Reiter, RE, Alumkal, JJ, Lara, PN   +63 more
core   +1 more source

Impact of Six‐Month Monitoring Compared to Three‐Month Monitoring of Laboratories During Methotrexate Therapy

Arthritis Care &Research, EarlyView.
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko, Ray Zhang, Sohini Mukherjee, Puneet Bajaj, Bonnie L. Bermas   +4 more
wiley   +1 more source

Associations of Frailty With the Risk of Incident Cancer and Cancer‐Related Mortality in Veterans With Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective This study investigated the association between frailty and cancer incidence and mortality in patients with rheumatoid arthritis (RA). It aimed to identify how frailty influences cancer risk and cancer‐specific outcomes. Methods This retrospective cohort study analyzed data from the Veterans’ Affairs Rheumatoid Arthritis Registry (2002–2023).
Bhavik Bansal, Aaron Baraff, Katherine Wysham, James S. Andrews, Bryant R. England, Ted R. Mikuls, Joshua Baker, Kaleb Michaud, Alexa Meara, Una Makris, Carolyn Presley, Ariela Orkaby, Namrata Singh   +12 more
wiley   +1 more source

Safety and efficacy of zolbetuximab plus chemotherapy for claudin 18 isoform 2-positive advanced gastric cancer: initial report of real-world experience

Journal of Cancer Research and Clinical Oncology
Purpose This study evaluated the safety and preliminary efficacy of zolbetuximab plus chemotherapy in patients with claudin 18 isoform 2 (CLDN18.2)-positive advanced gastric cancer (AGC).
Keitaro Shimozaki, Akira Ooki, Shota Fukuoka, Hiroki Osumi, Kaoru Yoshikawa, Koichiro Yoshino, Shohei Udagawa, Takeru Wakatsuki, Eiji Shinozaki, Mariko Ogura, Keisho Chin, Kensei Yamaguchi   +11 more
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Cancer Trends: Breast cancer 1994-2016

, 2019
There were 62,052 cases of newly diagnosed invasive or in situ breast tumours registered in Ireland by the National Cancer Registry for the period 1994–2016, of which 56,366 were invasive (ICD10: C50) and 5,686 were carcinoma in situ (ICD10: D05 ...
National Cancer Registry Ireland (NCRI)
core  

Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman, Mei Li, Xiudong Lei, Hui Zhao, Juan I. Ruiz, Sharon H. Giordano, Alexis R. Ogdie, Maria E. Suarez‐Almazor   +7 more
wiley   +1 more source

Cancer Trends: Cancer of unknown primary

, 2019
Between 2012 and 2016, over 450 patients per year were diagnosed with a malignant cancer where the primary site of their cancer was unspecified. These cancers were identified by the presence of metastatic disease where the cancer has spread to other ...
National Cancer Registry Ireland (NCRI)
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