Results 11 to 20 of about 4,823,404 (316)
Immunotherapy in Gastrointestinal Cancers [PDF]
BioMed Research International, 2017 Gastrointestinal cancers represent a major public health problem worldwide. Immunotherapeutic strategies are currently under investigation in this setting and preliminary results of ongoing trials adopting checkpoint inhibitors are striking. Indeed, although a poor immunogenicity for GI has been reported, a strong biological rationale supports the ...
Procaccio, Letizia +11 more
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PROTACs in gastrointestinal cancers
Molecular Therapy - Oncolytics, 2022 Proteolysis targeting chimera (PROTAC) presents a powerful strategy for targeted protein degradation (TPD). The heterobifunctional PROTAC molecule consists of an E3 ligase ligand covalently linked to a protein of interest (POI) via a linker. PROTAC can induce ubiquitinated proteasomal degradation of proteins by hijacking the ubiquitin-proteasome ...
Yu Chen +19 more
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Alkaloids in the treatment of gastrointestinal tract cancer [PDF]
, 2023 Alkaloids, nitrogen-containing compounds, are found in living organisms ranging from microbes to seed-producing plants all over the world. About more than 20,000 alkaloids have been discovered, mostly occurring in higher plants of the families ...
Sarfraz, Iqra +6 more
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, 2022 An educational session related to the Western Canadian Gastrointestinal Cancer Consensus Conference (WCGCCC) was held virtually on 14 October 2020. The WCGCCC is an interactive multidisciplinary conference attended by health care professionals from ...
Duc Le +43 more
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Novel Biomarkers of Gastrointestinal Cancer
, 2021 Gastrointestinal (GI) cancer is a major cause of morbidity and mortality worldwide [...
Takaya Shimura
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Autophagy in gastrointestinal cancers
Frontiers in Oncology, 2022 Gastrointestinal cancers are a group of cancers occurred in gastrointestinal tissues with high morbidity and mortality rate. Although numerous studies were conducted on the investigation of gastrointestinal cancers, the real mechanisms haven’t been discovered, and no effective methods of prevention and treatment of gastrointestinal cancers have been ...
Bo-Zong Shao +6 more
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Correlation between postoperative prognosis in gastrointestinal cancer patients and blastformation rate of lymphocytes [PDF]
, 1977 Gastrointestinal cancer patients were followed up for up to 30 months postoperatively and their clinical status related to a parameter of nonspecific immunity, the blastformation rate of peripheral blood lymphocytes against phytohemagglutinin.
Orita, Kunzo, Miwa, Hiroaki
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Epidemiology of gastrointestinal cancer [PDF]
Environmental Health Perspectives, 1974 Some 99,000 new cases of cancer of the colon are expected next year, an incidence rate higher than that for both cancer of the lung and cancer of the breast. Evidence from geographic pathology suggests that some environmental factors play a strong role in its etiology.
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, 2022 : Recently, we have witnessed impressive diagnostic and therapeutic changes for gastrointestinal cancer patients. New challenges brought by the COVID-19 pandemic have led us to re-evaluate our work priorities. Thanks to the commendable resilience of both
Wyrwicz, Lucjan +47 more
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Quality of life and chronic pain four years after gastrointestinal surgery [PDF]
, 2006 PURPOSE: Little is known about the prevalence of chronic postsurgical pain after gastrointestinal surgery. This study was designed to assess the prevalence of chronic pain and quality of life in a cohort of patients who underwent surgery for benign and ...
Krukowski, Zygmunt H., Bruce, Julie
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